Facing COVID-19 Via Anti-Inflammatory Mechanism of Action: Molecular Docking and Pharmacokinetic Studies of Six Anti-Inflammatory Compounds Derived from Passiflora edulis

References (60)

1. 1 AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading [DOI]
2. 2 SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules [DOI]
3. 3 pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures [DOI]
4. 4 A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 [DOI]
5. 5 Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19 [DOI]
6. 6 Clinical characteristics of 140 patients infected with SARS‐CoV‐2 in Wuhan, China [DOI]
7. 7 Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 — COVID-NET, 14 States, March 1–30, 2020 [DOI]
8. 8 SARS-CoV-2 infection: The role of cytokines in COVID-19 disease [DOI]
9. 9 A Bioavailability Score [DOI]
10. 10 Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture [DOI]
11. 11 Antioxidant and anti-inflammatory activities of quercetin and its derivatives [DOI]
12. 12 Flavonoids in Cancer and Apoptosis [DOI]
13. 13 Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment [DOI]
14. 14 The influence of sex and gender on the immune response [DOI]
15. 15 Virtual screening and repurposing of FDA approved drugs against COVID-19 main protease [DOI]
16. 16 Coronavirus breakthrough: dexamethasone is first drug shown to save lives [DOI]
17. 17 Antitumor, antioxidant and anti-inflammatory activities of kaempferol and its corresponding glycosides and the enzymatic preparation of kaempferol [DOI]
18. 18 Racial and Gender-Based Differences in COVID-19 [DOI]
19. 19 Computational analysis of calculated physicochemical and ADMET properties of protein-protein interaction inhibitors [DOI]
20. 20 Passiflora edulis: An Insight Into Current Researches on Phytochemistry and Pharmacology [DOI]
21. 21 Receptor-based virtual screening protocol for drug discovery [DOI]
22. 22 Evidence of anti-inflammatory effects of Passiflora edulis in an inflammation model [DOI]
23. 23 Analogous β-Carboline Alkaloids Harmaline and Harmine Ameliorate Scopolamine-Induced Cognition Dysfunction by Attenuating Acetylcholinesterase Activity, Oxidative Stress, and Inflammation in Mice [DOI]
24. 24 Identification of potential inhibitors of SARS-CoV-2 main protease from Aloe vera compounds: A molecular docking study [DOI]
25. 25 Natural compounds fromClerodendrumspp. as possible therapeutic candidates against SARS-CoV-2: Anin silicoinvestigation [DOI]
26. 26 As a potential treatment of COVID-19: Montelukast [DOI]
27. 27 Evaluation of the Anti-inflammatory Activity of Luteolin in Experimental Animal Models [DOI]
28. 28 Socioeconomic Differentials in Immune Response [DOI]
29. 29 Harmine is an inflammatory inhibitor through the suppression of NF-κB signaling [DOI]
30. 30 Pharmacological studies of Passiflora sp. and their bioactive compounds [DOI]
31. 31 Intestinal anti-inflammatory effects of Passiflora edulis peel in the dextran sodium sulphate model of mouse colitis [DOI]
32. 32 Aloe vera (L.) Burm. F. as a Potential Anti-COVID-19 Plant: A Mini-review of Its Antiviral Activity [DOI]
33. 33 Intake of Passiflora edulis leaf extract improves antioxidant and anti-inflammatory status in rats with 2,4,6-trinitrobenzenesulphonic acid induced colitis [DOI]
34. 34 Identification of a novel dual-target scaffold for 3CLpro and RdRp proteins of SARS-CoV-2 using 3D-similarity search, molecular docking, molecular dynamics and ADMET evaluation [DOI]
35. 35 Spectroscopic (FTIR, FT-Raman, 13C and 1H NMR) investigation, molecular electrostatic potential, polarizability and first-order hyperpolarizability, FMO and NBO analysis of 1-methyl-2-imidazolethiol [DOI]
36. 36 α-methylation and α-fluorination electronic effects on the regioselectivity of carbonyl groups of uracil by H and triel bonds in the interaction of U, T and 5FU with HCl and TrH3 (Tr = B, Al) [DOI]
37. 37 Interactions between temozolomide and guanine and its S and Se-substituted analogues [DOI]
38. 38 Pharmacoinformatics and molecular dynamic simulation studies to identify potential small-molecule inhibitors of WNK-SPAK/OSR1 signaling that mimic the RFQV motifs of WNK kinases [DOI]
39. 39 Review on Ethno-botany, Virucidal Activity, Phytochemistry and Toxicology of Solanum genus: Potential Bio-resources for the Therapeutic Management of Covid-19 [DOI]
40. 40 Is Inhaled Furosemide a Potential Therapeutic for COVID-19? [DOI]
41. 41 A Mini Review on the Phytochemistry, Toxicology and Antiviral Activity of Some Medically Interesting Zingiberaceae Species [DOI]
42. 42 Effect of Extracts of Passiflora edulis Leaves on Herpes Viruses Infection [DOI]
43. 43 Unravelling syn- and anti- orientation in the regioselectivity of carbonyl groups of 5-fluorouracil an anticancer drug toward proton donors [DOI]
44. 44 Semi-empirical Approach on the Methanogenic Toxicity of Aromatic Compounds on the Biogas Production [DOI]
45. 45 Docking of Human Heat Shock Protein 90 with Selenoderivatives of Geldanamycin [DOI]
46. 46 Evaluation of Pharmacokinetics, Antibacterial and Anti-Inflammatory Activities of Chrysin in Rat [DOI]
47. 47 Human Kidney is a Target for Novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection [DOI]
48. 48 Potential Inhibitor of COVID-19 Main Protease (Mpro) From Several Medicinal Plant Compounds by Molecular Docking Study [DOI]
49. 49 Nelfinavir was predicted to be a potential inhibitor of 2019-nCov main protease by an integrative approach combining homology modelling, molecular docking and binding free energy calculation [DOI]
50. 50 Reduced Vitamin K Status as A Potentially Modifiable Prognostic Risk Factor in COVID-19 [DOI]
51. 51 Drug repurposing approach to fight COVID-19 [DOI]
52. 52 Pulmonary and Extra-Pulmonary Clinical Manifestations of COVID-19 [DOI]
53. 53 Clinical Characteristics, Diagnosis, and Treatment of Major Coronavirus Outbreaks [DOI]
54. 54 Addition of Tocilizumab to the Standard of Care Reduces Mortality in Severe COVID-19: A Systematic Review and Meta-Analysis [DOI]
55. 55 Interaction between temozolomide and HCl: Preferred binding sites [DOI]
56. 56 Computational analysis by molecular docking of thirty alkaloid compounds from medicinal plants as potent inhibitors of SARS-CoV-2 main protease [DOI]
57. 57 Virtual Screening of an FDA Approved Drugs Database on Two COVID-19 Coronavirus Proteins [DOI]
58. 58 Facing COVID-19 via anti-inflammatory mechanism of action: Molecular docking and Pharmacokinetic studies of six anti-inflammatory compounds derived from Passiflora edulis [DOI]
59. 59 In vivo Evaluation and in silico Prediction of the Toxicity of Drepanoalpha Hard capsules [DOI]
60. 60 Drug Repurposing Against SARS-CoV-2 Using E-Pharmacophore Based Virtual Screening and Molecular Docking with Main Protease as the Target [DOI]

Cited by 12

Showing 6 of 12 known citations — external sources report more than can currently be individually listed.

Related research

• COVID 19 Disease Caused by Coronavirus 2 (SARS-CoV-2) (Severe Acute Respiratory Syndrome) — shares topic coverage
• Assessment of Anxiety in Healthcare Providers Working in ICU during COVID-19 Pandemics — shares topic coverage
• Azithromycin and Hydroxychloroquine Accelerate Recovery of Outpatients with Mild/Moderate COVID-19 — shares topic coverage
• Elevated Levels of Lactate Dehydrogenase Predicts Poor Outcomes for Patients with COVID-19: A Review — shares topic coverage
• Addressing the Challenges of Containing Covid-19 Spread in a Rural, Poor Area in India: A Case Study — shares topic coverage