Skip to content
K

Koto-Te-Nyiwa Ngbolua

Publications (40)

Review on Ethno-botany, Virucidal Activity, Phytochemistry and Toxicology of Solanum genus: Potential Bio-resources for the Therapeutic Management of Covid-19

Koto-Te-Nyiwa Ngbolua, Clément M. Mbadiko, Aristote Matondo, Gédéon N. Bongo, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Domaine T. Mwanangombo, Etienne M. Ngoyi, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana · European Journal of Nutrition & Food Safety · 2020

Background and Aim: Condiment plants are not only a source of food, flavors or food additives but also antivirals. The aim of the present work consisted in compiling ethno-botanical, phytochemical, toxicological and biological activities literature data reported on some species o...

Open access Research Article 10.9734/ejnfs/2020/v12i730246

Knowledge on the Environmental Disaster Occurrence in the Democratic Republic of the Congo: The Case of Flooding and Bushfire in Businga Territory, Nord Ubangi

Koto-Te-Nyiwa Ngbolua, André Nzamonga Gamo, Amédée Kundana Gbatea, Trésor Mbombo Limbaya, Adèle Chimanuka Mwinja, Gédéon Bongo Ngiala, Colette Masengo Ashande & Ruphin Djoza Djolu · Asian Journal of Geographical Research · 2019

Aims: The aim of this research was to assess the knowledge, perceptions and attitudes of victims and stakeholders on environmental disasters occurring in Businga territory. Study Design: This research employed a descriptive study design whereby the characteristics of respondents...

Open access Research Article 10.9734/ajgr/2019/v2i130077

Phytochemistry and Bioactivity of Annona reticulata L. (Annonaceae): A Mini-review

Koto-Te-Nyiwa Ngbolua, Clément L. Inkoto, Gédéon N. Bongo, Lengbiye E. Moke, Lufuluabo G. Lufuluabo, Colette Masengo Ashande, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana · South Asian Research Journal of Natural Products · 2018

Aims: To provide knowledge on phytochemistry and bioactivity of Annona reticulata. Study Design: Multidisciplinary advanced bibliographic surveys, utilization of ChemBioDraw software package and dissemination of the resulted knowledge. Place and Duration of Study: Faculty of Scie...

Open access Research Article

Localization and Distribution of Two Invasive Alien Species Eichhornia crassipes and Echinocloa pyramidalis in the Pool Malebo Eco-region, Democratic Republic of the Congo

Mukendi Tshibangu Michael, Koto-Te-Nyiwa Ngbolua, Mbale Kunzi Henri, Menga Munkolo Pisco & Lukoki Luyeye Félicien · Annual Research & Review in Biology · 2022

Aim: To study the distribution of two invasive alien plants and associated plants as well as their distribution in the Malebo Pool eco-region. Methodology: The study was carried out by direct observation by circulating on a motorized canoe. Plant samples were randomly harvested (...

Open access Research Article 10.9734/arrb/2022/v37i730516

Phytochemistry and Pharmacology of Aframomum angustifolium (Sonn.) K. Schum (Zingiberaceae): A Mini Review

Clément L. Inkoto, Koto-Te-Nyiwa Ngbolua, Patrick E. Bokungu, Colette A. Masengo, Jeff B. Iteku, Dorothée D. Tshilanda, Damien S. T. Tshibangu & Pius T. Mpiana · South Asian Research Journal of Natural Products · 2021

According to the World Health Organization (WHO), more than 80% of the population in Africa in general and in the Democratic Republic of the Congo (DRC) in particular, resorts to Traditional Medicine to solve the problem of primary health care. In this study we had reviewed the r...

Open access Research Article

A Mini Review on the Phytochemistry and Pharmacology of Aframomum alboviolaceum (Zingiberaceae)

Clément L. Inkoto, Koto-Te-Nyiwa Ngbolua, Jason T. Kilembe, Colette Masengo Ashande, Félicien L. Lukoki, Dorothée D. Tshilanda, Damien S-T. Tshibangu & Pius T. Mpiana · South Asian Research Journal of Natural Products · 2021

Background and Aims: Given the importance of finding a new Improved Traditional Medicine (ITM) based on medicinal plants, we reviewed the traditional uses, phytochemical composition, biological properties and toxicity of Aframomum alboviolaceum (Zingiberaceae), a plant species wi...

Open access Research Article

Assessment of Phytoecological Parameters of Forest Massifs in the Kwilu Province in the Democratic Republic of the Congo

Y. B. da-Musa Masens, Koto-Te-Nyiwa Ngbolua, Mandung Masens, John Makiadi Tambu Tembeni & Gédéon Ngiala Bongo · Asian Plant Research Journal · 2020

Rainforests constitute the great green heart of Africa and thus they present a unique combination of ecological, climatic and human interactions. The degradation of various forest ecosystems in mainly tropical regions and more particularly in sub-Saharan Africa has been a constan...

Open access Research Article 10.9734/aprj/2020/v6i430134

Aloe vera (L.) Burm. F. as a Potential Anti-COVID-19 Plant: A Mini-review of Its Antiviral Activity

Pius T. Mpiana, Koto-Te-Nyiwa Ngbolua, Damien S. T. Tshibangu, Jason T. Kilembe, Benjamin Z. Gbolo, Domaine T. Mwanangombo, Clément L. Inkoto, Emmanuel M. Lengbiye, Clément M. Mbadiko, Aristote Matondo, Gédéon N. Bongo & Dorothée D. Tshilanda · European Journal of Medicinal Plants · 2020

Aims: A novel β-coronavirus (2019-nCoV) has become a pandemic affecting hundreds of thousands of people worldwide. Since there is no effective treatment, the need of finding alternative methods which can help to curb this pandemic is urgent. This study aims to review the literatu...

Open access Research Article 10.9734/ejmp/2020/v31i830261

Laboratory Testing on the Promotion of Madagascar's Industrial Waste and Natural Materials as Clinker Mineralizers

Athou W. Razafindramanga, Koto-Te-Nyiwa Ngbolua, Gédéon N. Bongo & Baholy R. Rahelivololoniaina · Asian Journal of Geological Research · 2019

This study presented laboratory tests on the effects of several mineralizers added to black raw materials, in the manufacture of cement. This manufacturing process is based on crushing quarry limestones with clays and fuels in order to be fired at 1450°C to obtain clinker, the ma...

Open access Research Article

Antioxidant Potential and Anti-Sickling Activity of Different Organs of Curcuma longa: Correlation of the Antioxidant Capacity on Anti-Sickling Activity

Clément M. Mbadiko, Koto-Te-Nyiwa Ngbolua, Pius T. Mpiana, Nadège K. Ngombe, Paulin M. Kapepula, Landry L. Kemfine, Gédéon N. Bongo & Théophile F. Mbemba · South Asian Research Journal of Natural Products · 2019

Aims: The aim of this research was to evaluate comparatively the anti-sickling activity of aqueous and methanol extracts of different organs of C. longa, to determine the polyphenolic compounds and to evaluate the antioxidant potential of different parts of C. longa. Also, to est...

Open access Research Article

Synthesis and in vitro Antisickling Activity of Some Non-aromatic Esters

Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua, Damien S. T. Tshibangu, Augustin M. Malumba & Pius T. Mpiana · Chemical Science International Journal · 2015

Organic acids and their derivatives like butyl stearate have recently shown antisickling activity. Some none aromatic esters were synthetized and tested for their antisickling activity using Emmel test. On 21 esters tested only three showed no antisickling activity. Butyl palmita...

Open access Research Article 10.9734/ACSJ/2016/22734

Review of the Literature on Oral Cancer: Epidemiology, Management and Evidence-based Traditional Medicine Treatment

Mfutu Mana Charly, Sekele Issouradi Jean-PauI, Koto-Te-Nyiwa Ngbolua, Situakibanza Nani-Tuma Hippolyte, Kamangu Ntambwe Erick, Paul Bobe Alifi, Nzudjom Foche Adelin, Monizi Mawunu, Emmanuel Kitete Mulongo, Tukutuku Musombo Nanou Anne, Pius T. Mpiana & Pakasa Muyulu Nestor · Annual Research & Review in Biology · 2022

Oral cavity cancers are part of the upper aerodigestive tract cancers and represent a significant burden worldwide. Its epidemiology varies from country to country with high frequencies in South East Asian countries. Tobacco and alcohol are the main risk factors. Survival of oral...

Open access Research Article 10.9734/arrb/2022/v37i630512

Factors Favoring Non-compliance of Treatment to People Living with HIV/AIDS in General Reference Hospital of Gbadolite, Nord Ubangi, Democratic Republic of the Congo

Kohowe Pagerezo Seraphin, Gédéon Ngiala Bongo, Kumbali Ngambika Guy & Koto-Te-Nyiwa Ngbolua · Journal of Complementary and Alternative Medical Research · 2020

Background: ART is one of the important pillars of the fight against AIDS. It restores immunity and reduces the risk of death. Its success lies in its strict compliance while its non-compliance exposes to the risk of resistance and therapeutic failure. The objective of this study...

Open access Research Article 10.9734/jocamr/2020/v9i430147

Ethnobotanical and Socio-economics of Dracaena camerooniana Baker in Uíge Province, Northern Angola

Mawunu Monizi, Dionisio Canga André, Lukoki Luyeye, Koto-Te-Nyiwa Ngbolua & Luyindula Ndiku · Journal of Agriculture and Ecology Research International · 2019

Aims: The aim of this research was to contribute to the survey of ethnobotanical knowledge on the use of Dracaena camerooniana by the local communities’ bordering the tropical forests of Uíge province. Study Design: The data collections were carried out using the semi-structured...

Open access Research Article 10.9734/jaeri/2019/v20i230104

Effect of Drying on the Composition of Secondary Metabolites in Extracts from Floral Parts of Curcuma longa L.

Clément Mutunda Mbadiko, Gédéon Ngiala Bongo, Léonard Ukondalemba Mindele, Koto-Te-Nyiwa Ngbolua, Pius Tshimankinda Mpiana, Nadège Kabamba Ngombe, Paulin Kapepula Mutwale & Théophile Fundu Mbemba · Asian Journal of Research in Botany · 2019

Background: Curcuma longa is a rhizomatous herbaceous plant of Zingiberaceae family, originating from South Asia and very widespread in hot and rainy regions of the globe. The rhizomes are very popular spice and used as food additives for its coloring, aromatic, food preservation...

Open access Research Article

Adherence of Periodontal Patients to Supportive Therapy at the University Clinics of Kinshasa, Democratic Republic of the Congo

M. N. Patrick Sekele, I. Jacques Bolenge, Nzudjom Foche Adelin Baudouin, S. Willy Lusasi, Koto-Te-Nyiwa Ngbolua & I. B. Jean-Paul Sekele · Asian Journal of Dental Sciences · 2021

Aim of the Study: To determine the level of adherence of periodontal patients at the University Clinics of Kinshasa (CUK). Methodology: A cross-sectional study on adherence of periodontal patients to supportive therapy was conducted at CUK from 2016 to 2019. Patients who have suf...

Open access Research Article

In vitro Screening of the Leaf Extracts from Gardenia ternifolia (Forest Gardenia) for their Anticancer Activity

Damien S. Tshibangu, Selvaraj Divakar, Muthiah Ramanathan, Govindarajan G. Syamala, Koto-Te-Nyiwa Ngbolua, Virima Mudogo, Dorothée D. Tshilanda, Benjamin Z. Gbolo & Pius T. Mpiana · Journal of Complementary and Alternative Medical Research · 2016

Aim: The aim of the study is to evaluate the cytotoxicity of the crude extracts of Gardenia ternifolia (Oliv.) in human prostate cancer (PC-3) and breast cancer (MCF-7) cell lines. Study Design: Successive extractions of Gardenia ternifolia leaves were performed, using petroleum...

Open access Research Article 10.9734/JOCAMR/2016/28348

Quantitative Determination of Biochemical Constituents of the Wild Food Plant Talinum triangulare (Jacqu) Wild (Big Purslane)

Florent Biduaya Mukeba, Archil Ndub Ilunga, Prince Bofati Ilonga, Gédéon Ngiala Bongo, Myriam Ngondo Mukadi, Koto-Te-Nyiwa Ngbolua, Johnny Bopopi Mukoko, Nadège K. Ngombe, Paulin Kapepula Mutwale & Franck Kinungi Banzola · Asian Journal of Research in Biochemistry · 2021

The Democratic Republic of the Congo is one of the major biodiversity hotspot in the world. Wild edible plants (WEPs) are widely consumed as part of daily diet by the local people and are part of their traditional culture and food habit. The T. triangulare species is a non-conven...

Open access Research Article 10.9734/ajrb/2021/v8i130174

Mineral Content and Antisickling Activity of Annona senegalensis, Alchornea cordifolia and Vigna unguiculata Used in the Management of Sickle Cell Disease in the Kwilu Province (Congo, DR)

Jules M. Kitadi, Clément L. Inkoto, Emmanuel M. Lengbiye, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua, K. M. Taba, Blaise M. Mbala, Brigitte Schmitz & Pius T. Mpiana · International Blood Research & Reviews · 2020

Aims: To determine the mineral composition of some plants (Annona senegalensis Pers., Alchornea cordifolia (Schumach. & Thonn.) Müll. Arg. and Vigna unguiculate (L.) Walp.) used in the management of sickle cell disease by traditional practitioners in Kwilu province and to eva...

Open access Research Article 10.9734/ibrr/2020/v11i330131

Mineral Element Contents and Antisickling Activity of Cyttaranthus congolensis and Hypoxis angustifolia Traditionally Used to Treat Sickle Cell Disease in Kwilu Province, Democratic Republic of the Congo

Jules M. Kitadi, Clément L. Inkoto, Sha-Tshibey Tshibangu, Dorothée Dinangayi Tshilanda, Taba Kalulu, Papy Kawata, Koto-Te-Nyiwa Ngbolua & Pius Tshimankinda Mpiana · International Journal of Biochemistry Research & Review · 2022

The objective of the present study was to determine the composition in mineral elements, the antisickling activity and the osmotic brittleness test, of the twenty three extracts of two plants Cyttaranthus congolensis, Hypoxis angustifolia used in the management of sickle cell dis...

Open access Research Article 10.9734/ijbcrr/2022/v31i10790

Secondary Metabolites and Mineral Elements of Manotes expansa and Aframomum alboviolaceum Leaves Collected in the Democratic Republic of Congo

Carlos N. Kabengele, Giresse N. Kasiama, Etienne M. Ngoyi, Jason T. Kilembe, Juvenal Bete, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua, Dorothée D. Tshilanda & Pius T. Mpiana · Annual Research & Review in Biology · 2022

Background and Aims: Manotes expansa Sol. ex Planch. and Aframomum alboviolaceum (Ridl.) Schum.  are two plants belonging respectively to the family Connaraceae R.Br. and Zingiberaceae Martino widely used in traditional medicine for the treatment of eye diseases, fever, headaches...

Open access Research Article 10.9734/arrb/2022/v37i1130549

Ethnozoological Study on Ichthyotherapy among the Suku People (Feshi Territory, Kwango Province), Democratic Republic of the Congo

Victor Pwema Kiamfu, Patience Kivudi, Willy Lusasi Swana, Santos Kavumbu Mutanda, Clément Munganga Kilingwa, Angélique Osobo Yakolina, Koto-Te-Nyiwa Ngbolua & Jean-Claude Micha · Asian Journal of Research in Zoology · 2021

A survey was conducted from August 15, 2019 to February 20, 2020 among 67 traditional healers in order to know the species of fish that are used in the composition of traditional medicines used to treat some diseases in the Kambundi-Nganga Group, Ganaketi Sector, Feshi Territory...

Open access Research Article 10.9734/ajriz/2021/v4i330116

Semi-empirical Approach on the Methanogenic Toxicity of Aromatic Compounds on the Biogas Production

Beaudrique M. Nsimba, Norbert L. Basosila, Jean-Claude K. Kayembe, Didier M. Mbuyi, Aristote P. Matondo, Gédéon N. Bongo, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · Asian Journal of Applied Chemistry Research · 2020

In this work, a semi-empirical approach correlating the values of methanogenic toxicity of 22 aromatic compounds was used.  TheIC50 exp, along with the various molecular properties of these compounds were determined using the DFT B3LYP/6-31G (d,p) method. While a conceptual appro...

Open access Research Article 10.9734/ajacr/2020/v5i430146

Influence of the Socio-Economic Profile of the Head of Household on Domestic Energy Use for Cooking in the City of Uíge, Angola

Monizi Mawunu, Arlete E. T. Miguel, Iracelma J. Bengui, Nsimba F. E. Mawunu, Masidivinga Landu, Mayi Mbemba, Mbumbu Luswamu, Koto-Te-Nyiwa Ngbolua, Luyindula Ndiku & F. Lukoki Luyeye · Journal of Energy Research and Reviews · 2021

The city of Uíge, capital of the province of Uíge in northern Angola, presents a diversity of lifestyles, socio-economic levels and domestic energy sources for cooking. The present study aimed to identify the different domestic energy sources used in cooking operations in househo...

Open access Research Article 10.9734/jenrr/2021/v8i230207

Heavy Metal Content and Physico-Chemical Analyses of Soils under the Litter of some Medicinal Taxa in the Luki Biosphere Reserve, Democratic Republic of the Congo

Florent Biduaya Mukeba, Myriam Mukadi Ngondo, Nazaire Kabemba Kadima, Prince Bofati Ilonga, Patrick Kayembe Bibasuya, Patience Mpia Ngelinkoto, Paulin Kapepula Mutwale, Koto-Te-Nyiwa Ngbolua, Kalima Nkoma Mwange, Johnny Bopopi Mukoko, Nadège Kabamba Ngombe, Pius T. Mpiana & Théophile Mbemba Fundu · Asian Journal of Environment & Ecology · 2021

Aim: The aim of this study was to compare the texture, mineral element and heavy metal content of the soil under the litter of different selected species in relation to the plan of their pedogenesis. Methods: The granulometric analysis of the various samples based on laser diffra...

Open access Research Article 10.9734/ajee/2021/v14i330208

Knowledge and Practices on Biosafety in Clinical Laboratories of Kinshasa in the Democratic Republic of the Congo

Christian Amisi Motuta, Vivi Maketa, Hippolyte Mavoko Muhindo, Alain Mpanya, Symphorien Lubanza, Rodhain Mukele, Gédéon Ngiala Bongo, Koto-Te-Nyiwa Ngbolua & Pascal Tshindele Lutumba · Asian Journal of Medical Principles and Clinical Practice · 2020

Biosafety, as a set of measures to prevent laboratory acquired infections, has been recommended for more than fifty years. Indeed, since that time, evidence of contamination of laboratory workers has been provided in several articles. Are these measures known and applied in labor...

Open access Research Article

Effect of Gibberellic Acid on Seed Germination and Evaluation of Agrobacterium rhizogenes Strains for the Induction of "Hairy Roots" of Phyllanthus niruri Linn. (Phyllantaceae)

Florent Biduaya Mukeba, Gédéon Ngiala Bongo, Johnny Bopopi Mukoko, Freddy Otono Bulubulu, Myriam Mukadi Ngondo, Paulin Kapepula Mutwale, Odette Ngandu Kabena & Koto-Te-Nyiwa Ngbolua · Asian Journal of Biotechnology and Genetic Engineering · 2020

Phyllanthus niruri L. is a medicinal plant from tropical regions with great pharmacognosic virtues scientifically proven. It is a rare herbaceous wild species in the dry season. Its use for the pharmaceutical industry requires a regular supply and it is independent of climatic ha...

Open access Research Article

Literature Review on the Phytochemistry and Pharmaco-Biological, Nutritional and Cosmetic Properties of Lippia multiflora and New Research Perspectives

Masengo Ashande Colette, Emmanuel Lengbiye Moke, Clément Inkoto Liyongo, Benjamin Zoawe Gbolo, Dorothée Dinangayi Tshilanda, Damien Sha-Tshibey Tshibangu, Robijaona Rahelivololoniaina Baholy, Ilumbe Bayeli Guy, Koto-Te-Nyiwa Ngbolua, Pius T. Mpiana & Mudogo Virima · South Asian Research Journal of Natural Products · 2021

Background: Lippia multiflora is a wild/spontaneous food plant with numerous pharmaco-therapeutic activities and rich in terpenic and phenolic bioactive compounds whose valorization as nutaceutical can help a better management of chronic diseases. Objective: To make an inventory...

Open access Research Article

Facing COVID-19 Via Anti-Inflammatory Mechanism of Action: Molecular Docking and Pharmacokinetic Studies of Six Anti-Inflammatory Compounds Derived from Passiflora edulis

Aristote Matondo, Jason T. Kilembe, Domaine T. Mwanangombo, Beaudrique M. Nsimba, Dani T. Mawete, Benjamin Z. Gbolo, Gédéon N. Bongo, D. O. Opota, Koto-Te-Nyiwa Ngbolua, Dorothée D. Tshilanda, Damien S. T. Tshibangu, Virima Mudogo & Pius T. Mpiana · Journal of Complementary and Alternative Medical Research · 2021

Aim: In the most severe case of the COVID-19, there is an excessive production of proinflammatory cytokines, being the main cause of mortality and morbidity. The present study aims at assessing the potential inhibitor effect of six phytochemicals with anti-inflammatory activity d...

Open access Research Article 10.9734/jocamr/2020/v12i330211

Ethno-botanical Survey and Chemical Study of Medicinal Plants Traditionally used to Treat Anemia in Yakoma Territory (Nord Ubangi), Democratic Republic of the Congo

Samy Ngunde-Te-Ngunde, Kabengele N. Carlos, Emmanuel Moke Lengbiye, Jason Thambwe Kilembe, Jean-Aimé Mbanga Lokebo, Dorothée D. Tshilanda, Nadège Kabamba Ngombe, Pius T. Mpiana, Jeff Iteku Bekomo & Koto-Te-Nyiwa Ngbolua · Annual Research & Review in Biology · 2022

Aims of the Study: To identify plant species traditionally used to treat anemia in Yakoma territory and to evaluate their chemical composition. Place and Duration: Yakoma Territory (survey) and University of Kinshasa (Phytochemical study), from August and October 2019. Methods: E...

Open access Research Article 10.9734/arrb/2022/v37i430498

Leukocyte Profile of Children Hospitalized in Neonatology Services for Suspected Infection in Kinshasa City, Democratic Republic of the Congo

Rita Bokemposila, Clément L. Inkoto, Alexis Kazamwali, Gaston Mwema, Christian Lobinga, Louise Malonga, Jean Claude Malenga, Thérèse Mbeza, Jean Lambert Gini Ehungu, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Research and Reports in Hematology · 2021

Neonatal infection (NI) remains a public health problem of concern because of its frequency and severity, which is related to the immuno-incompetence of the newborn and the risk of mortality, which is in the order of 10% to 30%. According to the World Health Organization (WHO), 3...

Open access Research Article

Microscopic Features, Mineral Contents, Anti-sickling, Antioxidant and Antibacterial Activities of Stem Bark of Harungana madagascariensis Lam. Ex Poiret (Hypericaceae)

Florent Biduaya Mukeba, Johnny Bopopi Mukoko, Manix M. Mayangi, Myriam Mukadi Ngondo, Patience Mpia Ngelinkoto, Jérome V. Bamba, Fanfan Kitwa, Gédéon Ngiala Bongo, Paulin K. Mutwale, Koto-Te-Nyiwa Ngbolua, Nadège K. Ngombe, Pius T. Mpiana & Théophile F. Mbemba Mbemba · European Journal of Medicinal Plants · 2020

Aims: This study addressed the identification of bioactive compounds, the determination of mineral content and the evaluation of the antibacterial, antioxidant and anti-sickling activities of aqueous extract from stem bark of Harungana madagascariensis. Place and Duration of Stud...

Open access Research Article 10.9734/ejmp/2020/v31i2030355

Bioactivity and Nutritional Values of Some Dioscorea Species Traditionally Used as Medicinal Foods in Bandundu, DR Congo

F. C. Bukatuka, K. N. Ngombe, K. P. Mutwale, B. M. Moni, K. G. Makengo, L. A. Pambu, N. G. Bongo, M. P. Mbombo, M. D. Musuyu, U. Maloueki, Koto-Te-Nyiwa Ngbolua & F. T. Mbemba · European Journal of Medicinal Plants · 2016

Aims: To valorize traditional foods of the Democratic Republic of Congo in general and the province of Bandundu in particular by evaluating the antioxidant activity of five species of Dioscorea, the determination of their chemical composition as well the determination of their gl...

Open access Research Article 10.9734/EJMP/2016/25124

A Mini-review on the Phytochemistry and Pharmacobiology of Azadirachta indica A. Juss. (Meliaceae): Towards future research directions

Blaise Mbembo Wa Mbembo, Colette Masengo Ashande, Lionel Asamboa Shotsha, Samy Ngunde Te Ngunde, Blanchard Mayele Masasi, Joseph Tshidibi Dipa, Sylvain Zogi Ngbo, Jean-Jacques Amogu Domondo, Dorothée D. Tshilanda, Damien S. T. Tshibangu, Pius T. Mpiana & Koto-Te-Nyiwa Ngbolua · Journal of Complementary and Alternative Medical Research · 2021

Medicinal plants are suppliers of molecules used in both modern and traditional therapy. One of these plants is Azadirachta Indica (also known as the neem tree).Originally from Asia (India), this plant is currently widespread and cultivated in several countries in the world, incl...

Open access Research Article 10.9734/jocamr/2021/v15i230261

Antihelminthic Activity, Phytochemical Profile and Microscopic Features of Ocimum basilicum Collected in DR Congo

Carlos N. Kabengele, Etienne M. Ngoyi, Giresse N. Kasiama, Jason T. Kilembe, Aristote Matondo, Clément L. Inkoto, Emmanuel M. Lengbiye, Clément M. Mbadiko, Jean Jacques D. Amogu, Gédéon N. Bongo, Benjamin Z. Gbolo, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua, Dorothée D. Tshilanda & Pius T. Mpiana · Asian Journal of Biology · 2020

Aim: The main aim of the present study is to validate the bioactivity of O. basilicum, a medicinal plant traditionally used to treat helminthiasis in DRC. Place and Duration of Study: Department of Chemistry, Science Faculty, University of Kinshasa, between June 2018 and March 20...

Open access Research Article 10.9734/ajob/2020/v10i330110

A Mini Review on the Phytochemistry, Toxicology and Antiviral Activity of Some Medically Interesting Zingiberaceae Species

Clément M. Mbadiko, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Aristote Matondo, Domaine T. Mwanangombo, Etienne M. Ngoyi, Gédéon N. Bongo, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · Journal of Complementary and Alternative Medical Research · 2020

Background: Plants of the Zingiberaceae family namely Curcuma longa, Aframomum melegueta and Zingiber officinale are known for their many biological activities such as the antiviral activity. Aim: To provide an updated knowledge on the phytochemistry, toxicology and antiviral act...

Open access Research Article 10.9734/jocamr/2020/v9i430150

Ocimum Species as Potential Bioresources against COVID-19: A Review of Their Phytochemistry and Antiviral Activity

Dorothée D. Tshilanda, Etienne M. Ngoyi, Carlos N. Kabengele, Aristote Matondo, Gédéon N. Bongo, Clément L. Inkoto, Clément M. Mbadiko, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Domaine T. Mwanangombo, Giresse N. Kasiama, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Pathogen Research · 2020

Aim: The aim of this work was to review literature data reported on some species of the Ocimum genus regarding their phytochemistry and antiviral potential in order to show how Ocimum species might be used in the management of COVID-19. Methodology: Various databases like PubMed,...

Open access Research Article 10.9734/ijpr/2020/v5i430143

Possible Effect of Aromatic Plants and Essential Oils against COVID-19: Review of Their Antiviral Activity

Damien S. T. Tshibangu, Aristote Matondo, Emmanuel M. Lengbiye, Clément L. Inkoto, Etienne M. Ngoyi, Carlos N. Kabengele, Gédéon N. Bongo, Benjamin Z. Gbolo, Jason T. Kilembe, Domaine T. Mwanangombo, Clément M. Mbadiko, Shetonde O. Mihigo, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · Journal of Complementary and Alternative Medical Research · 2020

Aim: Till now, no specific treatment is available for COVID-19. This work is carried out with the aim of verifying in the literature the antiviral properties of aromatic plants and essential oils that can justify their use against the causative agent of COVID-19, SARS-CoV-2. Meth...

Open access Research Article 10.9734/jocamr/2020/v11i130175

Antiviral Activity, Phytochemistry and Toxicology of Some Medically Interesting Allium Species: A Mini Review

Emmanuel M. Lengbiye, Clément M. Mbadiko, Clarisse M. Falanga, Aristote Matondo, Clément L. Inkoto, Etienne M. Ngoyi, Carlos N. Kabengele, Gédéon N. Bongo, Benjamin Z. Gbolo, Jason T. Kilembe, Domaine T. Mwanangombo, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Shetonde O. Mihigo, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Pathogen Research · 2020

Aims: COVID-19 pandemic affects hundreds of thousands of people worldwide. Since there is no effective treatment, the need of finding alternative methods, which can help to curb this pandemic is urgent. This study aims to collect the information on the virucidal and toxicity prop...

Open access Research Article 10.9734/ijpr/2020/v5i430145

Oleanolic Acid, Ursolic Acid and Apigenin from Ocimum basilicum as Potential Inhibitors of the SARS-CoV-2 Main Protease: A Molecular Docking Study

Aristote Matondo, Jason T. Kilembe, Etienne M. Ngoyi, Carlos N. Kabengele, Giresse N. Kasiama, Emmanuel M. Lengbiye, Clément M. Mbadiko, Clément L. Inkoto, Gédéon N. Bongo, Benjamin Z. Gbolo, Clarisse M. Falanga, Domaine T. Mwanangombo, Daniel O. Opota, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Pathogen Research · 2021

Aim: The present study aims at identifying potential inhibitors from a set of ten compounds from Ocimum basilicum against the SARS-CoV-2 main protease, the chymotrypsin-like protease (3CLpro). Materials and Methods: Computational studies by molecular docking (Autodock tool) were...

Open access Research Article 10.9734/ijpr/2021/v6i230156