Aim: The aim of this study is to evaluate clinical, biological, socio-economic and socio-demographic parameters on sickle cell patients before, during and after the administration of Drepanoalpha®, a nutraceutical used in the management of sickle cell disease in DR. Congo. Method...
Open access
Research Article10.9734/JOCAMR/2017/37350
Aims: The aim of this study is to assess the efficacy and safety of Drepanoalpha®, a nutraceutical used in the management of sickle cell disease in DR Congo. Study Design: Drepanoalpha® to ten sickle patients, evaluation of parameters before and after treatment. Place and Duratio...
Open access
Research Article10.9734/IJMPCR/2017/33658
Clément M. Mbadiko, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Aristote Matondo, Domaine T. Mwanangombo, Etienne M. Ngoyi, Gédéon N. Bongo, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana·Journal of Complementary and Alternative Medical Research·2020
Background: Plants of the Zingiberaceae family namely Curcuma longa, Aframomum melegueta and Zingiber officinale are known for their many biological activities such as the antiviral activity. Aim: To provide an updated knowledge on the phytochemistry, toxicology and antiviral act...
Open access
Research Article10.9734/jocamr/2020/v9i430150
Pius T. Mpiana, Koto-Te-Nyiwa Ngbolua, Damien S. T. Tshibangu, Jason T. Kilembe, Benjamin Z. Gbolo, Domaine T. Mwanangombo, Clément L. Inkoto, Emmanuel M. Lengbiye, Clément M. Mbadiko, Aristote Matondo, Gédéon N. Bongo & Dorothée D. Tshilanda·European Journal of Medicinal Plants·2020
Aims: A novel β-coronavirus (2019-nCoV) has become a pandemic affecting hundreds of thousands of people worldwide. Since there is no effective treatment, the need of finding alternative methods which can help to curb this pandemic is urgent. This study aims to review the literatu...
Open access
Research Article10.9734/ejmp/2020/v31i830261
Aristote Matondo, Jason T. Kilembe, Domaine T. Mwanangombo, Beaudrique M. Nsimba, Dani T. Mawete, Benjamin Z. Gbolo, Gédéon N. Bongo, D. O. Opota, Koto-Te-Nyiwa Ngbolua, Dorothée D. Tshilanda, Damien S. T. Tshibangu, Virima Mudogo & Pius T. Mpiana·Journal of Complementary and Alternative Medical Research·2021
Aim: In the most severe case of the COVID-19, there is an excessive production of proinflammatory cytokines, being the main cause of mortality and morbidity. The present study aims at assessing the potential inhibitor effect of six phytochemicals with anti-inflammatory activity d...
Open access
Research Article10.9734/jocamr/2020/v12i330211
Koto-Te-Nyiwa Ngbolua, Clément M. Mbadiko, Aristote Matondo, Gédéon N. Bongo, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Domaine T. Mwanangombo, Etienne M. Ngoyi, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana·European Journal of Nutrition & Food Safety·2020
Background and Aim: Condiment plants are not only a source of food, flavors or food additives but also antivirals. The aim of the present work consisted in compiling ethno-botanical, phytochemical, toxicological and biological activities literature data reported on some species o...
Open access
Research Article10.9734/ejnfs/2020/v12i730246
Dorothée D. Tshilanda, Etienne M. Ngoyi, Carlos N. Kabengele, Aristote Matondo, Gédéon N. Bongo, Clément L. Inkoto, Clément M. Mbadiko, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Domaine T. Mwanangombo, Giresse N. Kasiama, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana·International Journal of Pathogen Research·2020
Aim: The aim of this work was to review literature data reported on some species of the Ocimum genus regarding their phytochemistry and antiviral potential in order to show how Ocimum species might be used in the management of COVID-19. Methodology: Various databases like PubMed,...
Open access
Research Article10.9734/ijpr/2020/v5i430143
Damien S. T. Tshibangu, Aristote Matondo, Emmanuel M. Lengbiye, Clément L. Inkoto, Etienne M. Ngoyi, Carlos N. Kabengele, Gédéon N. Bongo, Benjamin Z. Gbolo, Jason T. Kilembe, Domaine T. Mwanangombo, Clément M. Mbadiko, Shetonde O. Mihigo, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana·Journal of Complementary and Alternative Medical Research·2020
Aim: Till now, no specific treatment is available for COVID-19. This work is carried out with the aim of verifying in the literature the antiviral properties of aromatic plants and essential oils that can justify their use against the causative agent of COVID-19, SARS-CoV-2. Meth...
Open access
Research Article10.9734/jocamr/2020/v11i130175
Damien S. Tshibangu, Selvaraj Divakar, Muthiah Ramanathan, Govindarajan G. Syamala, Koto-Te-Nyiwa Ngbolua, Virima Mudogo, Dorothée D. Tshilanda, Benjamin Z. Gbolo & Pius T. Mpiana·Journal of Complementary and Alternative Medical Research·2016
Aim: The aim of the study is to evaluate the cytotoxicity of the crude extracts of Gardenia ternifolia (Oliv.) in human prostate cancer (PC-3) and breast cancer (MCF-7) cell lines. Study Design: Successive extractions of Gardenia ternifolia leaves were performed, using petroleum...
Open access
Research Article10.9734/JOCAMR/2016/28348
Emmanuel M. Lengbiye, Clément M. Mbadiko, Clarisse M. Falanga, Aristote Matondo, Clément L. Inkoto, Etienne M. Ngoyi, Carlos N. Kabengele, Gédéon N. Bongo, Benjamin Z. Gbolo, Jason T. Kilembe, Domaine T. Mwanangombo, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Shetonde O. Mihigo, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana·International Journal of Pathogen Research·2020
Aims: COVID-19 pandemic affects hundreds of thousands of people worldwide. Since there is no effective treatment, the need of finding alternative methods, which can help to curb this pandemic is urgent. This study aims to collect the information on the virucidal and toxicity prop...
Open access
Research Article10.9734/ijpr/2020/v5i430145
Aristote Matondo, Jason T. Kilembe, Etienne M. Ngoyi, Carlos N. Kabengele, Giresse N. Kasiama, Emmanuel M. Lengbiye, Clément M. Mbadiko, Clément L. Inkoto, Gédéon N. Bongo, Benjamin Z. Gbolo, Clarisse M. Falanga, Domaine T. Mwanangombo, Daniel O. Opota, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana·International Journal of Pathogen Research·2021
Aim: The present study aims at identifying potential inhibitors from a set of ten compounds from Ocimum basilicum against the SARS-CoV-2 main protease, the chymotrypsin-like protease (3CLpro). Materials and Methods: Computational studies by molecular docking (Autodock tool) were...
Open access
Research Article10.9734/ijpr/2021/v6i230156
Carlos N. Kabengele, Etienne M. Ngoyi, Giresse N. Kasiama, Jason T. Kilembe, Aristote Matondo, Clément L. Inkoto, Emmanuel M. Lengbiye, Clément M. Mbadiko, Jean Jacques D. Amogu, Gédéon N. Bongo, Benjamin Z. Gbolo, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua, Dorothée D. Tshilanda & Pius T. Mpiana·Asian Journal of Biology·2020
Aim: The main aim of the present study is to validate the bioactivity of O. basilicum, a medicinal plant traditionally used to treat helminthiasis in DRC. Place and Duration of Study: Department of Chemistry, Science Faculty, University of Kinshasa, between June 2018 and March 20...
Open access
Research Article10.9734/ajob/2020/v10i330110