Dorothée D. Tshilanda, Etienne M. Ngoyi, Carlos N. Kabengele, Aristote Matondo, Gédéon N. Bongo, Clément L. Inkoto, Clément M. Mbadiko, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Domaine T. Mwanangombo, Giresse N. Kasiama, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana·International Journal of Pathogen Research·2020
Aim: The aim of this work was to review literature data reported on some species of the Ocimum genus regarding their phytochemistry and antiviral potential in order to show how Ocimum species might be used in the management of COVID-19. Methodology: Various databases like PubMed,...
Open access
Research Article10.9734/ijpr/2020/v5i430143
Organic acids and their derivatives like butyl stearate have recently shown antisickling activity. Some none aromatic esters were synthetized and tested for their antisickling activity using Emmel test. On 21 esters tested only three showed no antisickling activity. Butyl palmita...
Open access
Research Article10.9734/ACSJ/2016/22734
Jules M. Kitadi, Clément L. Inkoto, Emmanuel M. Lengbiye, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua, K. M. Taba, Blaise M. Mbala, Brigitte Schmitz & Pius T. Mpiana·International Blood Research & Reviews·2020
Aims: To determine the mineral composition of some plants (Annona senegalensis Pers., Alchornea cordifolia (Schumach. & Thonn.) Müll. Arg. and Vigna unguiculate (L.) Walp.) used in the management of sickle cell disease by traditional practitioners in Kwilu province and to eva...
Open access
Research Article10.9734/ibrr/2020/v11i330131
Samy Ngunde-Te-Ngunde, Kabengele N. Carlos, Emmanuel Moke Lengbiye, Jason Thambwe Kilembe, Jean-Aimé Mbanga Lokebo, Dorothée D. Tshilanda, Nadège Kabamba Ngombe, Pius T. Mpiana, Jeff Iteku Bekomo & Koto-Te-Nyiwa Ngbolua·Annual Research & Review in Biology·2022
Aims of the Study: To identify plant species traditionally used to treat anemia in Yakoma territory and to evaluate their chemical composition. Place and Duration: Yakoma Territory (survey) and University of Kinshasa (Phytochemical study), from August and October 2019. Methods: E...
Open access
Research Article10.9734/arrb/2022/v37i430498
Clément L. Inkoto, Koto-Te-Nyiwa Ngbolua, Patrick E. Bokungu, Colette A. Masengo, Jeff B. Iteku, Dorothée D. Tshilanda, Damien S. T. Tshibangu & Pius T. Mpiana·South Asian Research Journal of Natural Products·2021
According to the World Health Organization (WHO), more than 80% of the population in Africa in general and in the Democratic Republic of the Congo (DRC) in particular, resorts to Traditional Medicine to solve the problem of primary health care. In this study we had reviewed the r...
Clément L. Inkoto, Koto-Te-Nyiwa Ngbolua, Jason T. Kilembe, Colette Masengo Ashande, Félicien L. Lukoki, Dorothée D. Tshilanda, Damien S-T. Tshibangu & Pius T. Mpiana·South Asian Research Journal of Natural Products·2021
Background and Aims: Given the importance of finding a new Improved Traditional Medicine (ITM) based on medicinal plants, we reviewed the traditional uses, phytochemical composition, biological properties and toxicity of Aframomum alboviolaceum (Zingiberaceae), a plant species wi...
Damien S. Tshibangu, Selvaraj Divakar, Muthiah Ramanathan, Govindarajan G. Syamala, Koto-Te-Nyiwa Ngbolua, Virima Mudogo, Dorothée D. Tshilanda, Benjamin Z. Gbolo & Pius T. Mpiana·Journal of Complementary and Alternative Medical Research·2016
Aim: The aim of the study is to evaluate the cytotoxicity of the crude extracts of Gardenia ternifolia (Oliv.) in human prostate cancer (PC-3) and breast cancer (MCF-7) cell lines. Study Design: Successive extractions of Gardenia ternifolia leaves were performed, using petroleum...
Open access
Research Article10.9734/JOCAMR/2016/28348
Carlos N. Kabengele, Giresse N. Kasiama, Etienne M. Ngoyi, Jason T. Kilembe, Juvenal Bete, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua, Dorothée D. Tshilanda & Pius T. Mpiana·Annual Research & Review in Biology·2022
Background and Aims: Manotes expansa Sol. ex Planch. and Aframomum alboviolaceum (Ridl.) Schum. are two plants belonging respectively to the family Connaraceae R.Br. and Zingiberaceae Martino widely used in traditional medicine for the treatment of eye diseases, fever, headaches...
Open access
Research Article10.9734/arrb/2022/v37i1130549
Koto-Te-Nyiwa Ngbolua, Clément L. Inkoto, Gédéon N. Bongo, Lengbiye E. Moke, Lufuluabo G. Lufuluabo, Colette Masengo Ashande, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana·South Asian Research Journal of Natural Products·2018
Aims: To provide knowledge on phytochemistry and bioactivity of Annona reticulata. Study Design: Multidisciplinary advanced bibliographic surveys, utilization of ChemBioDraw software package and dissemination of the resulted knowledge. Place and Duration of Study: Faculty of Scie...
Blaise Mbembo Wa Mbembo, Colette Masengo Ashande, Lionel Asamboa Shotsha, Samy Ngunde Te Ngunde, Blanchard Mayele Masasi, Joseph Tshidibi Dipa, Sylvain Zogi Ngbo, Jean-Jacques Amogu Domondo, Dorothée D. Tshilanda, Damien S. T. Tshibangu, Pius T. Mpiana & Koto-Te-Nyiwa Ngbolua·Journal of Complementary and Alternative Medical Research·2021
Medicinal plants are suppliers of molecules used in both modern and traditional therapy. One of these plants is Azadirachta Indica (also known as the neem tree).Originally from Asia (India), this plant is currently widespread and cultivated in several countries in the world, incl...
Open access
Research Article10.9734/jocamr/2021/v15i230261
Aristote Matondo, Jason T. Kilembe, Domaine T. Mwanangombo, Beaudrique M. Nsimba, Dani T. Mawete, Benjamin Z. Gbolo, Gédéon N. Bongo, D. O. Opota, Koto-Te-Nyiwa Ngbolua, Dorothée D. Tshilanda, Damien S. T. Tshibangu, Virima Mudogo & Pius T. Mpiana·Journal of Complementary and Alternative Medical Research·2021
Aim: In the most severe case of the COVID-19, there is an excessive production of proinflammatory cytokines, being the main cause of mortality and morbidity. The present study aims at assessing the potential inhibitor effect of six phytochemicals with anti-inflammatory activity d...
Open access
Research Article10.9734/jocamr/2020/v12i330211
Adam A. Ikey, Giresse N. Kasiama, Carlos N. Kabengele, Michel L. Kapembo, Etienne N. Matshimba, Juvenal Bete, Jason T. Kilembe, Clément L. Ikoto, K. N. Ngbolua, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana·International Journal of Pathogen Research·2022
Aims: The objective of this study was to determine the phytochemical profile of Centella asiatica, Citrus grandis and Zanthoxylum gilletii leaves, in solution and the thin layer chromatography chemical screening and to evaluate the antibacterial photodynamic activity of the speci...
Open access
Research Article10.9734/ijpr/2022/v9i230219
Giresse N. Kasiama, Adam Ikey, Carlos N. Kabengele, Jason T. Kilembe, Etienne N. Matshimba, Juvenal M. Bete, Prudent B. Bahati, Clément L. Inkoto, Paulin K. Mutwale, K. N. Ngbolua, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana·Annual Research & Review in Biology·2022
Aim: The objective of this study was to determine the phytochemical profile of Senna alata LINN using chemical screening in solution and thin-layer chromatography, and to assess the antioxidant and anthelmintic activities of the plant’s aqueous extracts. Methodology: All the anal...
Open access
Research Article10.9734/arrb/2022/v37i630513
Clément M. Mbadiko, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Aristote Matondo, Domaine T. Mwanangombo, Etienne M. Ngoyi, Gédéon N. Bongo, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana·Journal of Complementary and Alternative Medical Research·2020
Background: Plants of the Zingiberaceae family namely Curcuma longa, Aframomum melegueta and Zingiber officinale are known for their many biological activities such as the antiviral activity. Aim: To provide an updated knowledge on the phytochemistry, toxicology and antiviral act...
Open access
Research Article10.9734/jocamr/2020/v9i430150
Pius T. Mpiana, Koto-Te-Nyiwa Ngbolua, Damien S. T. Tshibangu, Jason T. Kilembe, Benjamin Z. Gbolo, Domaine T. Mwanangombo, Clément L. Inkoto, Emmanuel M. Lengbiye, Clément M. Mbadiko, Aristote Matondo, Gédéon N. Bongo & Dorothée D. Tshilanda·European Journal of Medicinal Plants·2020
Aims: A novel β-coronavirus (2019-nCoV) has become a pandemic affecting hundreds of thousands of people worldwide. Since there is no effective treatment, the need of finding alternative methods which can help to curb this pandemic is urgent. This study aims to review the literatu...
Open access
Research Article10.9734/ejmp/2020/v31i830261
Emmanuel M. Lengbiye, Clément M. Mbadiko, Clarisse M. Falanga, Aristote Matondo, Clément L. Inkoto, Etienne M. Ngoyi, Carlos N. Kabengele, Gédéon N. Bongo, Benjamin Z. Gbolo, Jason T. Kilembe, Domaine T. Mwanangombo, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Shetonde O. Mihigo, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana·International Journal of Pathogen Research·2020
Aims: COVID-19 pandemic affects hundreds of thousands of people worldwide. Since there is no effective treatment, the need of finding alternative methods, which can help to curb this pandemic is urgent. This study aims to collect the information on the virucidal and toxicity prop...
Open access
Research Article10.9734/ijpr/2020/v5i430145
Damien S. T. Tshibangu, Aristote Matondo, Emmanuel M. Lengbiye, Clément L. Inkoto, Etienne M. Ngoyi, Carlos N. Kabengele, Gédéon N. Bongo, Benjamin Z. Gbolo, Jason T. Kilembe, Domaine T. Mwanangombo, Clément M. Mbadiko, Shetonde O. Mihigo, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana·Journal of Complementary and Alternative Medical Research·2020
Aim: Till now, no specific treatment is available for COVID-19. This work is carried out with the aim of verifying in the literature the antiviral properties of aromatic plants and essential oils that can justify their use against the causative agent of COVID-19, SARS-CoV-2. Meth...
Open access
Research Article10.9734/jocamr/2020/v11i130175
Koto-Te-Nyiwa Ngbolua, Clément M. Mbadiko, Aristote Matondo, Gédéon N. Bongo, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Domaine T. Mwanangombo, Etienne M. Ngoyi, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana·European Journal of Nutrition & Food Safety·2020
Background and Aim: Condiment plants are not only a source of food, flavors or food additives but also antivirals. The aim of the present work consisted in compiling ethno-botanical, phytochemical, toxicological and biological activities literature data reported on some species o...
Open access
Research Article10.9734/ejnfs/2020/v12i730246
Carlos N. Kabengele, Etienne M. Ngoyi, Giresse N. Kasiama, Jason T. Kilembe, Aristote Matondo, Clément L. Inkoto, Emmanuel M. Lengbiye, Clément M. Mbadiko, Jean Jacques D. Amogu, Gédéon N. Bongo, Benjamin Z. Gbolo, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua, Dorothée D. Tshilanda & Pius T. Mpiana·Asian Journal of Biology·2020
Aim: The main aim of the present study is to validate the bioactivity of O. basilicum, a medicinal plant traditionally used to treat helminthiasis in DRC. Place and Duration of Study: Department of Chemistry, Science Faculty, University of Kinshasa, between June 2018 and March 20...
Open access
Research Article10.9734/ajob/2020/v10i330110
Aristote Matondo, Jason T. Kilembe, Etienne M. Ngoyi, Carlos N. Kabengele, Giresse N. Kasiama, Emmanuel M. Lengbiye, Clément M. Mbadiko, Clément L. Inkoto, Gédéon N. Bongo, Benjamin Z. Gbolo, Clarisse M. Falanga, Domaine T. Mwanangombo, Daniel O. Opota, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana·International Journal of Pathogen Research·2021
Aim: The present study aims at identifying potential inhibitors from a set of ten compounds from Ocimum basilicum against the SARS-CoV-2 main protease, the chymotrypsin-like protease (3CLpro). Materials and Methods: Computational studies by molecular docking (Autodock tool) were...
Open access
Research Article10.9734/ijpr/2021/v6i230156