Aims: Understanding the pattern of inhibitors binding to p-glycoprotein (Pgp). Study Design: Pgp is an ATP dependent transporter protein, responsible for multi-drug resistance in metastatic tumors. It removes toxins by exporting a variety of structurally unrelated compounds outsi...
Open access
Research Article10.9734/IJBCRR/2013/3268
Aims: The study was planned to see the effect of regular physical exercise on levels of lipid profile, activity of lecithin cholesterol acyl transferase, lipid peroxidation and antioxidant enzymes in those involved in regular physical exercise (among athlete in circus) and those...
Open access
Research Article10.9734/IJBCRR/2013/4711
Aims: Vinasse that is bottom product of distillation unit from alcohol industry contains Chemical Organic Compound (COD) in high concentration. The purpose of this study was to investigate the effect of COD/N ratios of substrate and pH control to biogas production from vinasse. S...
Open access
Research Article10.9734/IJBCRR/2013/3797
In the G protein-coupled receptors (GPCRs) relatively short regions of their intracellular loops and cytoplasmic C-terminal domain are responsible for specific interaction with G-proteins. GPCR-derived peptides corresponding to these regions are able to influence the activity of...
Open access
Research Article10.9734/IJBCRR/2013/5593
Three proteinaceous pheromone families, the androgen-binding proteins (ABPs), the exocrine-gland secreting peptides (ESPs) and the major urinary proteins (MUPs) are encoded by large gene families in the Mus musculus and Rattus norvegicus genomes. The purpose of this article is to...
Open access
Research Article10.9734/IJBCRR/2013/5763
Aims: To determine the role of human beta defensin-2 and oxidative stress by measuring serum human beta defensin-2 and antioxidant parameters in ovarian cancer patients. Study Design: Serum human beta defensin-2 (HBD-2), and the levels of antioxidants such as serum superoxide dis...
Open access
Research Article10.9734/IJBCRR/2013/5105
Aberrant Jagged1-mediated Notch activation is linked to cancer and induces epithelial-to-mesenchymal transition through the repression of E-cadherin transcription. All three proteins are subject to sequential proteolytic events referred to as regulated intramembrane proteolysis....
Open access
Research Article10.9734/IJBCRR/2013/3847
Purpose: This study was conducted to assess the effect of the ethyl acetate fraction (AcEF1) obtained from the 96% extract of Morinda morindoides extract on cardiac tissue integrity and function in rabbits. Methodology: The rabbits were divided in five groups of 6 rabbits e...
Open access
Research Article10.9734/IJBCRR/2013/4251
Aims: The present paper aims to study the effect of aromatic structure on the inhibition of biogas production and more specifically the effect of para substituted anilines functional groups (chemical structure) on methane biosynthesis by the digested pig manure methanogens. The o...
Open access
Research Article10.9734/IJBCRR/2013/2458
Glutathione S-transferase enzyme (GSTT1 and GSTM1) gene polymorphisms have been associated with the genetic susceptibility to end stage renal disease (ESRD) in different populations. We investigated the association between GSTT1 and GSTM1 genes, and ESRD in Egyptian population. T...
Open access
Research Article10.9734/IJBCRR/2013/4464