Evaluation of Genotoxic and Cytotoxic Activities of Cornsilk, (Stigma maydis) Extract of Zea mays L.
Chinyelu Clementina Osigwe, Jude E. Okokon, Ugonma Florence Uwaeme, Ezinne Mmekam, Imoh Imeh Johnny
Asian Journal of Biochemistry, Genetics and Molecular Biology · pp. 92–100 · Published 13 May 2025
10.9734/ajbgmb/2025/v17i4461Abstract
Allium cepa test was employed to evaluate genotoxic and cytotoxic potentials of cornsilk of Zea mays L. (Poacae), which is traditionally used as a remedy to various ailments. Macroscopic and microscopic analyses were carried out on Allium cepa root meristem cells exposed to cornsilk extract concentrations (2.5 mg/mL, 5 mg/mL, and 10 mg/mL). Tap water and Methotrexate (0.1 mg/mL) were used as negative and positive controls respectively. Significant (p< 0.05) inhibition of root growth by the cornsilk extract was observed which was concentration-dependent when compared with the negative control group. Cytotoxic effects such as suppression of cell division, induction of various chromosomal aberrations and micronuclei (MNC) formations were observed in the A. cepa root tips at all the tested extract’s concentrations. These observed aberrations were considerably significant (p<0.05) relative to the control group. The aberrations and damages observed following the extract treatment suggest cytotoxic and genotoxic potentials of the cornsilk extract of Z. mays on A. cepa.
Cited by 1
1 citation reported by external sources — individual citing-article records aren't available to list yet.
Related research
- Microbial and Metabolites Dynamics during the Fermentation of Artisanal Drinks: Screening and Estimation from “cha’a” and “arky” Consumed in Yaoundé-Cameroon — shares topic coverage
- Comparison of Antioxidant System and Anaerobic Metabolism in Seedlings of Contrasting Maize Genotypes under Short Term Waterlogging — shares topic coverage
- Cytotoxicological Response of Zea mays to Crude Oil: The Ecological Effects of Exposure to Contaminants — shares topic coverage
- Optimum Plant Density for Maximizing Yield of Six Inbreds and their F1 Crosses of Maize (Zea mays L.) — shares topic coverage
- Phytotoxic Effects of Aqueous Extracts of Olax subscorpioidea Oliv. on Seed Germination and Growth Parameters of Maize (Zea mays L.) — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
1
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.