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Chinyelu Clementina Osigwe

Publications (6)

Inhibitory Potential of Tetrapleura tetraptera Fruit Extract on Alpha Amylase and Alpha Glucosidase Activities in Rats

Chinyelu Clementina Osigwe, Ugonma Florence Uwaeme, Jude Efiom Okokon & Utibe Anietie Edem · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Diabetes mellitus is a metabolic disorder posing a serious global health concern, necessitating the need for investigation for alternative management and treatment strategies including phytomedicine. Tetrapleura tetraptera (Taub) (family Fabaceae, a medicinal plant used locally i...

Open access Research Article 10.9734/ajbgmb/2025/v17i7476

Evaluation of Genotoxic and Cytotoxic Activities of Cornsilk, (Stigma maydis) Extract of Zea mays L.

Chinyelu Clementina Osigwe, Jude E. Okokon, Ugonma Florence Uwaeme, Ezinne Mmekam & Imoh Imeh Johnny · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Allium cepa test was employed to evaluate genotoxic and cytotoxic potentials of cornsilk of Zea mays L. (Poacae), which is traditionally used as a remedy to various ailments. Macroscopic and microscopic analyses were carried out on Allium cepa root meristem cells exposed to corns...

Open access Research Article 10.9734/ajbgmb/2025/v17i4461

Genotoxic and Cytotoxic Activities of Leaf Extract of Stachytarpheta cayenensis (Rich). Vahl

Chinyelu Clementina Osigwe, Jude E. Okokon, Ugonma Florence Uwaeme & Imoh Imeh Johnny · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

The many pharmacological potentials of Stachytarpheta cayennensis (L.C. Rich) Vahl, (Verbenaceae), commonly called blue snakeweed and its use in traditional medicine in Nigeria such as in the treatment of hypertension, diabetes, mental illness and infections, could position it as...

Open access Research Article 10.9734/ajbgmb/2025/v17i4454

Antiulcer Activity of Justicia insularis Leaf Extract on Experimentally-Induced Ulcers in Rats

Ugonma Florence Uwaeme, Chinyelu Clementina Osigwe & Jude Efiom Okokon · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Peptic ulcer disease (PUD) is a significant gastrointestinal disorder that affects millions of people worldwide, imposing substantial burden on individuals, healthcare systems and economies. The available treatment options are not devoid of attendant sequalae. The search for less...

Open access Research Article 10.9734/ajbgmb/2025/v17i4457

Analgesic Activity of Alchornea laxiflora Stembark Extract in Mice

Jude E. Okokon, Anwangabasi E. Udoh, Chinyelu Clementina Osigwe, Ugonma Florence Uwaeme & Henry Thomas Okon · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Alchornea laxiflora is used in Ibibio ethnomedicine for the treatment of various diseases such as pains. This work was designed to validate and confirm the ethnomedical use of this plant in the treatment of pain.  The ethanol stembark extract of Alchornea laxiflora (141-424 mg/kg...

Open access Research Article 10.9734/ajbgmb/2025/v17i6470

Subacute Toxicity Study of Stem Extract of Telfairia occidentalis in Rats

Ukeme Essien Andrew, Jude Efiom Okokon, Chinyelu Clementina Osigwe, Ugonma Florence Uwaeme & Uduak Peter Isenigeri · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2025

Telfairia occidentalis Hook (Cucurbitaceae) is used in Ibibio ethnomedicine for the treatment of diverse diseases such as malaria, diabetes and gastrointestinal disorders.  Evaluation of subacute administration of ethanol stem extract of Telfaira occidentalis for effect on hemato...

Open access Research Article 10.9734/ajbgmb/2025/v17i2440