Zea mays L (Family-Poaceae) husk locally use as a remedy for various diseases was investigated for effect on hematological indices, liver and kidney functions as well as lipid profile and organs histologies after chronic administration of Zea mays ethanol husk extract to female W...
Open access
Research Article10.9734/jocamr/2025/v26i8693
Alchornea laxiflora is used in Ibibio ethnomedicine for the treatment of various diseases such as pains. This work was designed to validate and confirm the ethnomedical use of this plant in the treatment of pain. The ethanol stembark extract of Alchornea laxiflora (141-424 mg/kg...
Open access
Research Article10.9734/ajbgmb/2025/v17i6470
The leaves and fruits of Solanum anomalum Thonn. ex Schumach are used locally for the treatment of pains, fever and malaria among others. Effect of 90-day repeated administration of S. anomalum leaf extract on rats was investigated. Oral administration of the leaf extract (70, 14...
Open access
Research Article10.9734/jocamr/2025/v26i1614
The leaves of Saccharum officinarum (Family-Poaceae) is employed traditionally for ethnotherapy of malaria and fever among others. Evaluation of subacute administration of Saccharum officinarum leaf extract for possible effect on organs of rats was carried out. The leaf extract (...
Open access
Research Article10.9734/jocamr/2025/v26i1611
Hippocratea africana root is used locally in ethnomedicine to treat various diseases such as diabetes, malaria and poisoning. This work aimed to investigate the antidotal potential of the root extract and fractions against carbon tetrachloride induced liver injury to justify its...
Open access
Research Article10.9734/jocamr/2024/v25i8561
Mammea africana, a medicinal plant, used in ethnomedicine for the treatment of malaria, diabetes, poisoning and inflammatory diseases was investigated for cytotoxic and genotoxic effects on the root meristem cells of Allium cepa. Onion bulbs were exposed to 2.5 mg/mL, 5mg/mL, and...
Open access
Research Article10.9734/ajbgmb/2024/v16i5374
Solanum anomalum, a medicinal plant, used in ethnomedicine for their antimalarial, antidiabetic, and antiphlogistic activities was investigated for cytotoxic and genotoxic effects on the root meristem cells of Allium cepa. The extract and fractions was also screened for total fla...
Open access
Research Article10.9734/ajbgmb/2023/v15i3343
Aims: Analysis of cytotoxic effect, and correlation of in vitro and in vivo antimalarial activities of the root extract and fractions of H. africana so as to identify the active fraction. Methodology: The extract (200, 400, 600 mg/kg) and fractions (400 m/kg) were evaluated in mi...
Jude E. Okokon, Augustine I. L. Bassey, Emmanuel E. Nyong & Utibe A. Edem·Asian Journal of Biology·2020
Background: Croton zambesicus Muell Arg. (Euphorbiaceace) is a medicinal plant used traditionally in the treatment of some ailments. Aim: The root extract of Croton zambesicus was evaluated for effect on the gastrointestinal tract (GIT). Materials and Methods: The root extract of...
Open access
Research Article10.9734/ajob/2020/v10i230103
Solanum anomalum Thonn. ex Schumach, belonging to the family Solanaceae is a medicinal plant used among various cultures especially in Africa. The fruits and leaves have been in use nutritionally and ethnomedically for the treatment of diabetes, gastrointestinal ailments, malaria...
Open access
Research Article10.9734/jocamr/2025/v26i8687
Allium cepa test was employed to evaluate genotoxic and cytotoxic potentials of cornsilk of Zea mays L. (Poacae), which is traditionally used as a remedy to various ailments. Macroscopic and microscopic analyses were carried out on Allium cepa root meristem cells exposed to corns...
Open access
Research Article10.9734/ajbgmb/2025/v17i4461
The many pharmacological potentials of Stachytarpheta cayennensis (L.C. Rich) Vahl, (Verbenaceae), commonly called blue snakeweed and its use in traditional medicine in Nigeria such as in the treatment of hypertension, diabetes, mental illness and infections, could position it as...
Open access
Research Article10.9734/ajbgmb/2025/v17i4454
Background: Panicum maximum root is used routinely to treat ailments such as malaria, fever, pains and inflammatory diseases by traditional medicine practitioners. Aim: The study evaluated the anti-inflammatory effect of P. maximum root so as to validate its uses by practitioners...
Open access
Research Article10.9734/ajob/2020/v10i230101
The study evaluates the toxicity concern of a polyherbal mixture (Dr Iguedo Goko Cleanser®) on liver function parameters and liver histoarchitecture of exposed Wistar rats of both gender. Thirty (30) Wistar rats of both genders were randomly allotted to (6) six groups (5/group)....
Godswill J. Udom, Jude E. Okokon, John A. Udobang, Daniel N. Obot & Nkechi J. Onyeukwu·Asian Journal of Biology·2020
Dr Iguedo Goko Cleanser® is a polyherbal mixture promoted as an effective herbal remedy for numerous diseases. Study aimed to evaluate the toxicity concern of the polyherbal mixture (PHM) on lipid profile and oxidative status in Wistar rats of both gender. Acute toxicity study wa...
Open access
Research Article10.9734/ajob/2020/v9i430093
Aims: This study was designed to evaluate the toxicity concern of Dr Iguedo Goko Cleanser® on kidney function parameters and histoarchitecture of the kidneys of exposed Wistar rats. Study Design: A 60-day subchronic toxicological assessment using animal model. Place and Duration...
Open access
Research Article10.9734/ajrimps/2020/v9i130144
Telfairia occidentalis Hook (Cucurbitaceae) seed, which is used in the preparation of soups and as medicine traditionally to treat various diseases by the Ibibios, was investigated for its effect on hematological parameters, liver and kidney functions, and histology in male Wista...
Open access
Research Article10.9734/jocamr/2025/v26i6661
Aim: The antidotal potential of Hippocratea africana root, which is used locally to cure poisoning, was studied in rats. Methodology: The hepatoprotective activity of the root extract (200-600 mg/kg), fractions (dichloromethane (DCM) and aqueous, 400 mg/kg) and Silymarin (100 mg/...
Open access
Research Article10.9734/ajbgmb/2023/v15i3344
Hormonal imbalance and hypertrophy of internal organs are sensitive indices of toxicity which may be multifactorial (including exposure to certain foods, drugs and herbal remedies), and are implicated in certain conditions such as infertility amongst others. Dr Iguedo Goko Cleans...
Open access
Research Article10.9734/ajrre/2020/v3i129