Determinants and Prevalence of Metabolic Syndrome in Subjects Attending the General Outpatient Department of the Federal Medical Centre Katsina State, North West Nigeria

Abstract

Metabolic Syndrome (MS) is a term that describe the presence of conditions that increase an individual risk for heart disease and other disorders such as diabetes and stroke, and its occurrence is in the rise in residents of North-Western Nigeria, The aim of this study was to investigate the prevalence and determinants of metabolic syndrome in respondents from Katsina senatorial zone attending the Out-patient Department of the Federal Medical Center Katsina, Katsina State, Nigeria. A total of 211 (male 109; female 102) respondents aged 10 to 80 years were recruited for the study. Anthropometric parameters and blood pressure of respondents were determined using standard methods; serum lipid profile was determined using enzymatic methods. From the results, 11.8% of the male respondents were under weight, 51.6% were within the normal range, 25.4% of the study male population was found to be overweight and 12.8% were obese. 13.5% of the female respondents were under weight, 51.9% were within the normal range, 22.8% of the study female population was found to be overweight and 13.1% were obese. All serum lipids measurements with the exception of serum LDL-C concentration correlated positively with age. There were no statistically significant differences between the frequencies of total cholesterol, HDL, LDL and TRIG between the male and female respondents. The most common form of Dyslipidemia in the male and female respondents is low HDL-C. BMI, SBP, LDL-C, HDLC and TRIG were associated metabolic syndrome with the association being significant for SBP and HDL-C (0.05; 0.03) in the male respondent, in the female respondents BMI, SBP, DBP, LDL-C and TRIG were associated metabolic syndrome with the association being significant for SBP, DBP, and TRIG (0.04; 0.04; 0.04) respectively. The prevalence of metabolic syndrome was highest in male (31.75%) than in the female respondents (28.33).The prevalence of metabolic syndrome is common in the population under study with the male respondents having the highest prevalence. A robust and well design intervention program by concerned authorities is desirable to address complications of the risk factors for metabolic syndrome in the population.