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A. J. Alhassan

Publications (34)

Correlation Analysis of Toxic Metals Distribution and Pollution Indices in Soil, Beans and Maize Samples of Kano State, Nigeria

A. J. Alhassan, I. U. Muhammad, M. S. Sule, M. A. Dangambo, A. M. Gadanya, Y. Umar, Misbahu A. Dangambo, A. Mohammed & M. Syed · Annual Research & Review in Biology · 2019

Correlational study and evaluation of pollution indices of toxic metals distribution in soil and crops of a population are imperative for assessing the risk of chronic diseases associated with these metals. Correlational analysis for the distribution of; lead (Pb), cadmium (Cd),...

Open access Research Article 10.9734/arrb/2019/v32i330086

Characterization and Anti-diabetic Activity of Dihydrophenantherene Isolated from Khaya senegalensis Stem Bark

A. J. Alhassan, I. U. Muhammad, M. S. Sule, A. M. Wudil, A. A. Imam, A. Idi, A. Muhammad, A. Mohammed, I. Alexander & A. Nasir · Annual Research & Review in Biology · 2017

Khaya senegalensis A. Juss (Meliaceae), is regarded as the most popular medicinal meliaceous plant. The present study was conducted to evaluate anti-diabetic potentials of column chromatography fractions (FI-FVII) from ethyl acetate extract of Khaya senegalensis stem bark and det...

Open access Research Article 10.9734/ARRB/2017/35908

Evaluation of the Proximate Contents of Bambara Groundnut Vigna subterranean (L.) Verdc Grown in MadobiLGA, Kano State, Nigeria

A. J. Alhassan, M. A. Dangambo & T. M. Abdulmumin · Current Journal of Applied Science and Technology · 2015

Introduction: Evaluating the proximate composition of locally utilized crop with nutritional and industrial potentials is a timely gesture. Aim: The study was to determine the proximate contents of Bambara Groundnut (Vigna subterranean (L.) Verdc) grown in MadobiLGA, Kano state,...

Open access Research Article 10.9734/BJAST/2015/16577

Effects of Aqueous Extract of Some Selected Vegetables on Halofantrine Hepato-cardiatoxicity in Rats

A. J. Alhassan, M. S. Sule, A. M. Wudil & U. Lawan · Journal of Pharmaceutical Research International · 2014

Aim: The protective effect of some selected vegetables {Moringa (Moringa oleifera), Cabbage (Brassica oleracea) and Tomato (Solanum lycopersicum)} against hepato- cardio toxicity of halofantrine (an antimalarial drug) was evaluated in 72 albino rats. Study Design: The rats were g...

Open access Research Article 10.9734/BJPR/2014/7644

Sub-fractions from Carica Papaya Seed Extracts Can Prevent Potassium Bromate- induced Changes in Activities of Renal Brush Border Membrane Enzymes and Some Enzymes of Carbohydrate Metabolism in the Kidney of Rats

M. A. Kanadi, A. J. Alhassan, A. I. Yaradua, A. Nasir & A. M. Wudil · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2021

Aim: To investigate the effect of the chromatographic fractions of Carica papaya seed on KBrO3 –induced reduction in the activities of renal brush border membrane (BBM) marker enzymes and the changes in activities of some enzymes of carbohydrate metabolism in the kidney of rats....

Open access Research Article 10.9734/ajbgmb/2021/v8i430198

Determinants and Prevalence of Metabolic Syndrome in Subjects Attending the General Outpatient Department of the Federal Medical Centre Katsina State, North West Nigeria

A. I. Yaradua, A. J. Alhassan, M. K. Atiku, M. A. Wudil, K. I. Matazu, A. Nasir, Z. A. Suleiman, F. Usman, L. Shuaibu, A. Idi, I. U. Muhammad, Y. K. Bello, M. Alkali, S. Sule & A. A. Yaradua · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2020

Metabolic Syndrome (MS) is a term that describe the presence of conditions that increase an individual risk for heart disease and other disorders such as diabetes and stroke, and its occurrence is in the rise in residents of North-Western Nigeria, The aim of this study was to inv...

Open access Research Article 10.9734/ajbgmb/2020/v5i130118

Human Health Risk Assessment of Heavy Metals in Onion Bulbs Cultivated in Katsina State, North West Nigeria

A.I. Yaradua, A. J. Alhassan, A. Nasir, S. S. Matazu, A. Usman, A. Idi, I. U. Muhammad, S. A. Yaro & R. Nasir · Archives of Current Research International · 2020

Vegetable fields in Katsina State are increasingly being loaded with heavy metals through various pollution sources such as agricultural activities mining and traffic. Onion bulb samples from the three senatorial zones that constitute to make up Katsina state in the North West of...

Open access Research Article 10.9734/acri/2020/v20i230175

Heavy Metals Health Risk Assessment through Consumption of Baobab Leaf Cultivated in Katsina State, North West Nigeria

A. I. Yaradua, A. J. Alhassan, A. Nasir, K. I. Matazu, A. Usman, A. Idi, I. U. Muhammad, L. A. Saulawa & M. A. Dangambo · Asian Food Science Journal · 2019

Vegetables play important roles in human nutrition and health. They can also contain some undesirable components that can be harmful, e.g.  Pesticides and heavy metals. The objectives of the study were mainly to detect the presence of heavy metals (Cr, Cd, Fe, Ni, Mn, Pb and Zn)...

Open access Research Article 10.9734/afsj/2019/v13i130096

Health Risk Assessment for Carcinogenic and Non-carcinogenic Heavy Metal Exposures from Pepper Fruits Cultivated In Katsina State, North West Nigeria

A. I. Yaradua, A. J. Alhassan, A. Nasir, S. S. Matazu, A. Usman, A. Idi, I. U. Muhammad, L. Shuaibu & H. Ibrahim · Asian Journal of Advanced Research and Reports · 2019

This study was conducted to determine the heavy metals concentration in pepper fruits cultivated in Katsina state Nigeria. The objectives were mainly to detect the presence of heavy metals in the cultivated pepper fruits in the study area, compare the concentration of heavy metal...

Open access Research Article 10.9734/ajarr/2019/v6i430161

Acute Toxicity Studies and Phytochemical Constituents of Different Solvents Extracts of Carica papaya Seeds

M. A. Kanadi, A. J. Alhassan, A. L. Ngwen, A. I. Yaradua, A. Nasir & A. M. Wudil · Asian Journal of Research in Botany · 2019

Aim: To investigate the effect of five extraction solvents of varying polarity, namely aqueous, methanol, ethyl acetate, chloroform and n-hexane on phytochemicals yield and composition of Carica papaya seed. The acute toxicity test of each solvent fraction was also carried out an...

Open access Research Article

Concentrations and Risk Evaluation of Selected Heavy Metals in Amaranthus (L.) Leaf Cultivated in Katsina State, North West Nigeria

A. I. Yaradua, A. J. Alhassan, A. Nasir, K. I. Matazu, A. Usman, A. Idi, I. U. Muhammad, S. A. Yaro & Y. Y. Muhammad · Journal of Applied Life Sciences International · 2019

Bioaccumulation of seven heavy metals (Cr, Cd, Fe, Ni, Mn, Pb and Zn) in  Amaranthus leaf cultivated in Katsina state Nigeria were measured using atomic absorption spectrometer. The health risks to the local inhabitants from the consumption of the Amaranthus leaf were evaluated b...

Open access Research Article 10.9734/jalsi/2019/v20i430089

Heavy Metal Burden and Evaluation of Human Health Risks in Tomato Fruits Cultivated in Katsina State, North West Nigeria

A. I. Yaradua, A. J. Alhassan, A. Nasir, M. Bala, A. Usman, A. Idi, I. U. Muhammad, S. A. Yaro & I. Muhammad · Asian Food Science Journal · 2019

This study was conducted to determine the heavy metals concentration in Tomato fruits cultivated in Katsina State Nigeria. The objectives were mainly to detect the presence of heavy metals in the cultivated Tomato fruits in the study area, compare the concentration of heavy metal...

Open access Research Article 10.9734/afsj/2019/v9i130001

Evaluation of Health Effect of Some Selected Heavy Metals in Maize Cultivated in Katsina State, North West Nigeria

A. I. Yaradua, A. J. Alhassan, L. A. Saulawa, A. Nasir, K. I. Matazu, A. Usman, A. Idi, I. U. Muhammad & A. Mohammad · Asian Plant Research Journal · 2019

This study was conducted to determine the heavy metals concentration in maize cultivated in Katsina state Nigeria. The objectives were mainly to detect the presence of heavy metals in the cultivated maize in the study area, compare the concentration of heavy metals in samples in...

Open access Research Article 10.9734/aprj/2019/v2i330048

Health Risk Assessment for Carcinogenic and Non Carcinogenic Heavy Metal Exposure from Hibiscus Leaf Cultivated in Katsina State, North West Nigeria

A. I. Yaradua, A. J. Alhassan, A. Nasir, K. I. Matazu, A. Usman, S. Yau, A. Idi, I. U. Muhammad, S. A. Yaro & J. A. Mashi · Asian Journal of Agricultural and Horticultural Research · 2019

This study was conducted to determine the heavy metals concentration in Hibiscus leaves cultivated in Katsina State Nigeria. The objectives were mainly to detect the presence of heavy metals in the cultivated Hibiscus leaves in the study area, compare the concentration of heavy m...

Open access Research Article 10.9734/ajahr/2019/v3i430003

Amino Acid Profile and Mineral Content of Balanites aegyptiaca Kernel

I. U. Muhammad, A. J. Alhassan, Y. Ramatu, A. Mohammad, A. Nasir, A. I. Yaradua, I. Alexander, Y. Umar & M. D. Ezema · Asian Journal of Applied Chemistry Research · 2018

Study on the evaluation of the nutritional quality of poorly utilized plant products is of immense importance. This research work, therefore, evaluates the amino acid profile and mineral content of Balanites aegyptiaca kernel using standard analytical methods. The amino acid prof...

Open access Research Article 10.9734/ajacr/2018/v1i49683

Heavy Metals Health Risk Index (HRI) in Human Consumption of Whole Fish and Water from Some Selected Dams in Katsina State Nigeria

A. I. Yaradua, A. J. Alhassan, A. U. Kurfi, A. Nasir, A. Idi, I. U. Muhammad & A. M. Kanadi · Asian Journal of Fisheries and Aquatic Research · 2018

This study was conducted in the year 2016 to determine the heavy metal concentrations in whole fish (Clarias gariepinus) samples and water obtained from some selected Dams (Ajiwa, Zobe and Dannakola) in Katsina state Nigeria. The objectives were mainly to detect the presence of h...

Open access Research Article 10.9734/ajfar/2018/v1i1241

Pyretheroids Resistance and Detoxifying Enzymes Activities of Malaria Vector (Anopheles gambiae) Breeding in Auyo Irrigation and Residential Sites, Jigawa State, Nigeria

M. Safiyanu, A. J. Alhassan, A. A. Imam & H. Abdullahi · Annual Research & Review in Biology · 2017

Aims: The aim of this study is to evaluate the resistance status and detoxification enzymes activities of important malaria vector (Anopheles gambae) to WHO recommended pyretheroids insecticides in a highly malaria endemic country like Nigeria. Study Design: Mosquitoes larvae col...

Open access Research Article 10.9734/ARRB/2017/36025

Anti-Hyperglycemic Activity of Solvents Extract of Khaya senegalensis Stem Bark in Alloxan Induced Diabetic Rats

I. U. Muhammad, A. J. Alhassan, M. S. Sule, A. Idi, A. Mohammed, A. B. El- ta’alu, M. A. Dangambo & Y. Abdulmumin · Journal of Advances in Biology & Biotechnology · 2016

Introduction: Diabetes mellitus is among the major global public health problems and its prevalence is currently increasing at an alarming rate. According to the International Diabetes Federation, about 366 million people are living with diabetes and this figure is projected to i...

Open access Research Article 10.9734/JABB/2016/25986

Effect of Aqueous Stem Bark Extract of Khaya senegalensis (ASBEKS) on Lipid Profile in Diet Induced Hyperlipidemic Rats

I. U. Muhammad & A. J. Alhassan · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

In this study, aqueous stem bark extract of Khaya senegalensis (ASBEKS) was administered to hyperlipidemic rats to evaluate its effects on lipid parameters. Fifty (50) albino rats were divided into five groups (I, II, III, IV and V) of ten rats each. Group I served as normal cont...

Open access Research Article 10.9734/JAMPS/2016/25500

Toxicological and Protective Effect of Aqueous Stem Bark Extract of Khaya senegalensis (ASBEKS) on Liver of Experimental Rat

I. U. Muhammad, A. J. Alhassan, A. M. Wudil & I. K. Jarumi · Current Journal of Applied Science and Technology · 2015

The use of medicinal plant to prevent and or cure liver problems is a practice not peculiar to developing countries. This research work evaluated oral LD50 and hepatoprotective properties of aqueous stem bark extract of Khaya senegalensis (ASBEKS) in rats. The rats were grouped i...

Open access Research Article 10.9734/BJAST/2015/16545

Toxicity Study of Ricinus cummunis Lnn Seed Suspension in Female Wister Albino Rats

B. Y. Muhammad, A. J. Alhassan & I. J. Jaafaru · International Journal of Biochemistry Research & Review · 2015

Toxicity Study of Ricinus cummunis Lnn Seed Suspension in Female Wister Albino Rats Ricinus communis seed has been proven effective to prevent conception since time immemorial. This research focuses on the toxicity study of the seed suspension in Wister albino rats. Twenty four (...

Open access Research Article 10.9734/IJBCRR/2015/17511

Health Risk Assessment of Some Selected Heavy Metals in Agricultural Soils from Katsina State, North-Western Nigeria

A. I. Yaradua, L. Shuaibu, A. J. Alhassan, J. I. Bungudu, A. Usman, A. Nasir & I. A. Yaradua · Asian Journal of Applied Chemistry Research · 2022

This work contributes to the monitoring of heavy metal pollution of Agricultural soils, Katsina State Nigeria, using Atomic Absorption Spectrophotometry. The heavy metal contamination of the soil samples were analyzed based on the Geoaccumulation index (Igeo), enrichment factor (...

Open access Research Article 10.9734/ajacr/2022/v11i4209

Effect of Solvents Fractions of Cucurbita maxima Cuticular Lipids on Metabolic Biomarkers of Cardiovascular Disease

A. Idi, M. K. Atiku, A. J. Alhassan & I. U. Muhammad · European Journal of Medicinal Plants · 2022

This study was aimed at studying the effect of solvents (n-hexane, chloroform and methanol) fractions of Cucurbita maxima (pumpkin) cuticular lipids on metabolic biomarkers of cardiovascular disease using L-NAME induced hypertensive rats. A total of thirty-six (120-150 g) albino...

Open access Research Article 10.9734/ejmp/2022/v33i830481

Characterisation and Hypolipidaemic Activity of Phenylquinoline, and Narceine Isolated from Ficus polita Leaf

A. Nasir, M. S. Sule, A. J. Alhassan, M. K. Atiku, Y. Y. Muhammad, A. Idi, I. U. Muhammad, A. I. Yaradua, K. I. Matazu & M. B. Isah · International Journal of Biochemistry Research & Review · 2020

Aim: To evaluate hypolipidaemic potentials of column chromatography fractions (F1 to F6) of the chloroform leaf extract of Ficus polita and to detect the bioactive compounds present in the most active fraction using spectroscopic techniques. Study Design:  Fourty-five (45) wistar...

Open access Research Article 10.9734/ijbcrr/2020/v29i830211

Characterisation and Anti-diabetic Activity of Phenylquinoline, and Narceine Isolated from Ficus polita Leaf

A. Nasir, M. S. Sule, A. J. Alhassan, A. M. Wudil, A. A. Imam, A. Idi, I. U. Muhammad, A. I. Yaradua, K. I. Matazu & A. M. Kanadi · Annual Research & Review in Biology · 2020

The present study was conducted to evaluate anti-diabetic potentials of column chromatography fractions (F1-F6) of chloroform leaf extract of Ficus polita and to detect the probable bioactive compounds present in the most active fraction using spectroscopic techniques. Antidiabet...

Open access Research Article 10.9734/arrb/2020/v35i730251

Dose-Dependent Chemopreventive Effect of Methanol Extract of Carica papaya Seed on Potassium Bromate- Induced Nephrotoxicity in Rats

M. A. Kanadi, A. M. Wudil, A. J. Alhassan, A. L. Ngwen, A. I. Yaradua & A. Nasir · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2019

Aim: To investigate the effect of Carica papaya seed extract on KBrO3 - induced nephrotoxicity in rats. Renal toxicity was induced by a single oral dose of 100 mg/kg body weight of KBrO3. Study Design: Thirty (30) male albino rats were divided into six groups, five rats per group...

Open access Research Article 10.9734/ajbgmb/2019/v2i130051

Prevalence of Kidney Dysfunction among Orthopaedic Patients in Northwestern Nigeria

S. M. Adamu, A. M. Wudil, A. J. Alhassan, M. N. Salihu, Y. A. Koki, S. Adamu, A. M. Musa, S. A. Abdullahi, B. R. Usaini, I. U. Muhammad & A. Ibrahim · Journal of Advances in Medicine and Medical Research · 2017

Kidney dysfunction in orthopaedic cases may be as a result of kidney injury due to fracture, burns, osteomyelitis, spinal injury, spinal tuberculosis, sickle cell disease and various forms of arthritis. This study aimed at evaluating the biomarkers of kidney dysfunction among pat...

Open access Research Article 10.9734/JAMMR/2017/31640

Acute Toxicity and Hypoglycemic Activity of Aqueous Fruit Pulp Extract of Adansonia digitata L. (Afpead) on Alloxan Induced Diabetic Rats

I. U. Muhammad, I. K. Jarumi, A. J. Alhassan, A. M. Wudil & M. A. Dangambo · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Oral LD50 and hypoglycemic activity of aqueous fruit pulp extract of Adansonia digitata L. (AFPEAD) were investigated in this research. A total of fourty eight (48) rats were used, twelve (12) of the rats were used for oral LD50 determination, and were grouped into four (4) group...

Open access Research Article 10.9734/JAMPS/2016/23862

Heavy Metals and Health Risk Burden, How Safe is the Consumer Population?: A Study on the Heavy Metal Content of Soybeans Cultivated in Katsina State, North West Nigeria

A. I. Yaradua, J. I. Bungudu, L. Shuaibu, A. J. Alhassan, A. Nasir, U. Bello, A. Usman, Z. A. Suleiman, A. Abdullahi, M. M. Muhammad & I. A. Yaradua · Asian Journal of Applied Chemistry Research · 2022

The level of heavy metals in soybeans samples were evaluated to ascertain their likely health risks to the Katsina State populace. Atomic absorption spectrometry method was employed for the evaluation, while the three senatorial zones of the state were used for sampling. Using me...

Open access Research Article 10.9734/ajacr/2022/v11i430261

Effects of Ficus sycomorus Phenolic Extracts on the Activity of Hyaluronidase and Phospholipase A2 Enzymes of Echis ocellatus Venom

A. U. Hassan, M. S. Makeri, U. O. Ozojiofor & A. J. Alhassan · Asian Journal of Biotechnology and Genetic Engineering · 2020

Envenomation by snake is one of the most neglected public health problems in Nigeria, causing around 100,000 human deaths annually. It however remains a serious medical, economic and social problem. This research is aimed at evaluating the effects of F. sycomorus extract fraction...

Open access Research Article

Phytochemical Screening, Acute and Sub-chronic Toxicity Studies of Aqueous Stem Bark Extract of Ficus polita

A. Nasir, A. Hamisu, A. I. Yaradua, I. U. Muhammad, A. J. Alhassan, M. S. Sule, A. Idi, A. Mohammed & A. M. Kanadi · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2017

Ficus polita Vahl is a tropical African evergreen shrub or small tree belonging to the family Moraceae, and usually growing up to 15 metres tall. Extracts from different part of the plant had been demonstrated to exhibit various medicinal activities. Qualitative phytochemical scr...

Open access Research Article 10.9734/AJRIMPS/2017/38032

Effects of Lime Juice and Honey on Lipid Profile of Cholesterol Enriched Diet Fed Rat Model

A. Idoko, V. P. O. Ikpe, N. O. Nelson, J. U. Effiong, A. J. Alhassan, I. U. Muhammad, N. Abubakar & S. M. Abubakar · Annual Research & Review in Biology · 2017

Aims: To investigate the effects of lime juice and honey on lipid profile in albino wistar rats fed varying concentrations of cholesterol enriched diet. Study Design: The study was designed in two phases; phase I and phase II. Place and Duration of Study: Department of Biochemist...

Open access Research Article 10.9734/ARRB/2017/37213

In vitro Antimalarial Activity of Solvents Extracts of Alstonia boonei Stem Bark and Partial Characterization of Most Active Extract(s)

A. A. Imam, M. K. Atiku, I. U. Muhammad, M. D. Ezema, A. J. Alhassan, A. Idi, A. Mohammed, H. Abdullahi & I. Alexander · Journal of Pharmaceutical Research International · 2017

Alstonia boonei, a plant locally called ‘Egbu’ in South Eastern Nigeria is used traditionally in the treatment of malaria in the region. This research was carried out to evaluate in vitro antimalarial activity of different solvents extract (aqueous, methanol, ethyl acetate, chlor...

Open access Research Article 10.9734/JPRI/2017/36236

In vivo Antimalarial Activity of Solvents Extracts of Alstonia boonei Stem Bark and Partial Characterization of Most Active Extract(s)

A. A. Imam, M. D. Ezema, I. U. Muhammad, M. K. Atiku, A. J. Alhassan, A. Idi, H. Abdullahi & A. Mohammed · Annual Research & Review in Biology · 2017

Alstonia boonei, a plant locally called ‘Egbu’ in South Eastern Nigeria is used traditionally in the treatment of malaria in the region. This research was carried out to evaluate in vivo antimalarial activity of different solvents extract (aqueous, methanol and chloroform) of Als...

Open access Research Article 10.9734/ARRB/2017/36235