Aripiprazole, a known second generation anti-psychotic drug has been implicated to possess an anti-inflammatory potential, but yet not scientific adequately explored. This study investigated the role of aripiprazole in the resolution of acute peripheral inflammation in male wista...
Open access
Research Article10.9734/JPRI/2017/32601
Aims: The search for plant-based treatments against atopic dermatitis (AD), a relapsing dermatological condition with high prevalence in tropical regions, has always been attracting special attention. Among many folk remedies for AD, Oroxylum indicum Linn (Bignoniaceae) is a comm...
Open access
Research Article10.9734/JPRI/2017/34325
Aims: Allium sativum (Garlic) possesses antioxidant principles and is consumed widely as a nutritional agent and for medicinal purposes. This work investigated the effects of aqueous Garlic bulb extract on alloxan-induced plasma elevations of hepatic enzymes and renal biochemical...
Open access
Research Article10.9734/JPRI/2017/34909
Aims: The development of new beneficial agents is one of the crucial aims in medicinal chemistry. Isatin is considered as a vital class of bioactive compounds exhibiting different biological activities. A series of nine new Semicarbazone (12a-i) and six new Thiosemicarbazone (14a...
Open access
Research Article10.9734/JPRI/2017/35243
Tenofovir (TDF), used in combination with other antiretroviral agents, is an effective therapy for HIV infection. However, prolonged use of this drug is limited by a life threatening nephrotoxicity. Phoenix reclinata is a common palm species native to tropical Africa and is commo...
Open access
Research Article10.9734/JPRI/2017/34247
Objectives: The design of effective and safe novel drug delivery systems has become an integral part for the development and formulating of new medicines. So, research continuously keeps on searching for new ways to deliver drugs over a long period of time or for a well-controlle...
Open access
Research Article10.9734/JPRI/2017/34305
Metformin Hydrochloride has characteristic nature of lump formation and determination of particle size with reproducible result is difficult and particle size determination method is not reported in literature. Hence novel rugged and reproducible method has been developed for the...
Open access
Research Article10.9734/JPRI/2017/33911
Background: To make reimbursement decisions for orphan medicines the regulators need robust evidences for their efficacy and safety provided by systematic reviews and meta-analyses. The goal of the current study is to evaluate the efficacy and safety of orphan medicines included...
Open access
Research Article10.9734/JPRI/2017/34031
Aims: To evaluate whether the co-administration of benzodiazepines (BDZ) and selective serotonin and serotonin/norepinephrine reuptake inhibitors (SSRI/SNRI) during pregnancy is associated with an increased risk of abstinence symptoms in the newborns. Methods: Twenty six neonates...
Open access
Research Article10.9734/JPRI/2017/34620
Background: Annually, a large number of students tend to study pharmacy. Students enthusiastically begin their studies; however, they lose their tendency over time. This study addresses motives and effective factors on pharmacy major selection as well as factors which discourage...
Open access
Research Article10.9734/JPRI/2017/31530