The study assessed molecular interactions between the actives in antimalarial dihydroartemisinin-piperaquine (DP) tablet and food components using Fourier transform infrared spectroscopy (FTIR). Soluble starch, lactose, albumin, sunflower oil and carbonated drinks were pelletized...
Open access
Research Article10.9734/JPRI/2017/28516
Aim: This study was conducted to investigate the preventive or therapeutic effect of α-glucosidase inhibitor voglibose in a new model rat, Spontaneously Diabetic Torii-Leprfa (SDT fatty) rat, which is a novel type 2 diabetic rat showing obesity, hyperglycemia and hyperlipidemia f...
Open access
Research Article10.9734/BJPR/2014/13553
Background: Common cold is a self limited viral infection, which can be treated symptomatically without the need to antibiotics which are not effective or curative. This study aimed to evaluate the practices of community pharmacists in communicating, diagnosing, treating and coun...
Open access
Research Article10.9734/BJPR/2014/13586
The seeds of Cola nitida were investigated for their anti-diabetic properties. The extracts were obtained by maceration in cold water. Alloxan was used to induce diabetes mellitus (DM) in the rats at 180mg/kg body weight and diabetes was confirmed after 48 hours. The Phytochemica...
Open access
Research Article10.9734/BJPR/2014/13071
Aims: This study explores the total quantity of sulfur secondary metabolites in the plant organs of garlic and ramsons, the content of total phenol and their correlation to the antioxidant capacity (AOC). There are different reports about correlation of secondary sulfur compounds...
Open access
Research Article10.9734/BJPR/2014/13977
Aims: Screening total alkaloidal extract from Alstonia boonei root bark for antimicrobial and wound healing activity. Methodology: The anti-microbial screening was performed using the agar well diffusion method and the excision wound model was employed for the wound healing exper...
Open access
Research Article10.9734/BJPR/2014/13952
Background: Silver nanoparticles (SNPs) rapid involvement in industry and nanomedicine increased human exposure to variable forms of these particles, with possible potential risk on human health. Aims: The aim of this study is to investigate the biochemical changes induced by var...
Open access
Research Article10.9734/BJPR/2014/14666
Aims: Metformin Hydrochloride, a biguanide, is an orally active antihyperglycemic agent, used in the treatment of non-insulin dependent diabetes mellitus (NIDDM). It has relatively short plasma half life, low absolute bioavailability. Extended release formulation of Metformin Hyd...
Open access
Research Article10.9734/BJPR/2014/14013
Objective: To investigate the anti-diarrhoea property of aqueous leaves extract of Psidium guajava (red apple guava leaves) in castor oil-induced diarrhoea in rats. Methods: Five groups of five rats each orally received the following treatment; groups II, III & IV received 10...
Open access
Research Article10.9734/BJPR/2014/13297
Biomedical investigations still rely on the use of laboratory animals, mice and rats are the most commonly used on experimentations. Past experimentations with these animals showed that they could be affected by environmental conditions and infections, causing interferences on re...
Open access
Research Article10.9734/BJPR/2014/14294