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Journal of Pharmaceutical Research International

Published by SCIENCEDOMAIN international · ISSN (electronic) 2456-9119

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7,450

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84

2026 articles

7,450

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20,711

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Articles (7450)

Anti-inflammatory Activity and In silico Approaches on Root Extract of Decalepis hamiltonii Wight & Arn

Palanisamy Prakash & Rengarajan Manivasagaperumal · Journal of Pharmaceutical Research International · 2017

Aims: The present study was aimed to evaluate anti-inflammatory and antioxidant potential of methanol root extract of Decalepis hamiltonii. Results: The methanolic extract showed in vitro anti-inflammatory activity inhibition cells 96.1%µg/ml. MTT (3-(4,5-dimethylthiazol-2-yl)-2,...

Open access Research Article 10.9734/JPRI/2017/32070

The Effects of Kolaviron on the Atherogenic Propensity of Nigeria Local Edible Oils in Male Wistar Rats

Olulola Olutoyin Oladapo, Oluwafemi Majeed Quadri, Kehinde Ojora & Rotimi Sunday Ajani · Journal of Pharmaceutical Research International · 2017

Background: Dyslipidemia is partly dependent on consumption of edible oils. We set out to determine the atherogenic effects of commonedible oils in Nigeria, in male Wistar rats and to find out if administration of oral kolaviron amelioratedthese effects. Methods: Forty-eight male...

Open access Research Article 10.9734/JPRI/2017/35360

Regulatory Aspects of Omega Polyunsaturated Fatty Acids in Dietary Supplements

Valentina Petkova, Danka Obreshkova, Bozhidarka Hadzhieva & Stefka Ivanova · Journal of Pharmaceutical Research International · 2017

Background: Food additives are subject to certain regulatory requirements, as in some countries, the control is very strict, while in others there is almost no control. Some food supplements can affect existing diseases or interact with some medications, food and beverage, a fact...

Open access Research Article 10.9734/JPRI/2017/35627

Outcome of Pharmacists Health Belief Perception and Knowledge of CVD Risk Factors Intervention among Rural Community Dwellers

David U. Adje, Azuka C. Oparah & Felicia E. Williams · Journal of Pharmaceutical Research International · 2017

Background: Cardiovascular risk factor reduction strategies are more likely to be successful if persons at risk have a good knowledge of the disease and a positive perception of adopting cardio protective behavior .The objectives of this study were to assess the impact of communi...

Open access Research Article 10.9734/JPRI/2017/35064

Kigelia africana Stem Bark, Fruit and Leaf Extracts Alleviate Benzene-induced Leukaemia in Rats

Akanni E. Olufemi, Olaniran I. Omotayo, Akinbo B. David, Iyiola Monjeed, Ogunlade Adebola, Sanni Bilikis & Adejumo Temitope · Journal of Pharmaceutical Research International · 2017

Aims: This study was aimed at evaluating the potential leukaemia chemotherapeutic activities of various extracts of Kigelia africana stem bark; fruit and leaf by using a benzene-induced model of leukaemia to validate its folkloric use. Evidences from African herbal medicine and t...

Open access Research Article 10.9734/JPRI/2017/34625

Archachatina marginata Haemolymph Potentiates Hypoglycemic Effect by Mimicking Insulin in Streptozotocin-Induced Diabetic Rat

S. K. Adeboye, A. T. Ogundajo, O. O. Ajayi & O. M. Oluba · Journal of Pharmaceutical Research International · 2017

Aims: This study investigates the hypoglycemic potential of Archachatina marginata haemolymph and its mechanism in streptozotocin -induced diabetic rats. Study Design: One factor experimental design. Place and Duration of Study: Department of Chemical Sciences, Joseph Ayo Babalol...

Open access Research Article 10.9734/JPRI/2017/33786

Potential Antioxidant and Anti-Proliferative Activities of Biologically Active Marine Algae Extracts

Taha A. Kumosani, Khadijah Saeed Balamash, Hanaa Ghashlan, Youssri Ahmed Mohamed, Othman A. S. Baothman, Mustafa Zeyadi, Soonham Sami Yaghmoor, Areej H. Alyahiby, Rana R. AL-Rasheed, Wafa Y. Alturkistani, Tahani M. Alghamdi, Maryam H. AL-Zahrani & Said Salama Moselhy · Journal of Pharmaceutical Research International · 2017

Background: Marine microorganisms such as algae were identified a rich sources of biologically active compounds. This study was designed to explore the in vitro antioxidant, anti-apoptotic and anti proliferative activities of different algae [Gracilaria dendroides (GD), Dictyota...

Open access Research Article 10.9734/JPRI/2017/38089

Effect of Levetiracetam in the Treatment of Refractory Seizure in Infants through EEG: The Case of the Neonatal Intensive Care Unit of Tehran’s Children’s Medical Center

Malihe Kadivar, Mahboobeh Mohammadi, Ziba Mosayebi, Reza Shervinbadv, Raziee Sangsari & Bahram Yarali · Journal of Pharmaceutical Research International · 2017

Objective: Phenobarbital, phenytoin and Benzodiazepins are the most common treatments for resistant neonatal seizure [1]. Drug of choice in the treatment of neonatal seizure should be more effective and have fewer side effects. This study examines the effect of Levetriacetam (LEV...

Open access Research Article 10.9734/JPRI/2017/33922

Assessment of Antibiotic Self-medication Pattern among University Students in Eastern Democratic Republic of the Congo

Gabriel Kambale Bunduki, Mupenzi Mumbere & François Katsuva Mbahweka · Journal of Pharmaceutical Research International · 2017

Background: Self-medication with antibiotics has been reported among university students in many countries, but no study has been conducted on this issue in Democratic Republic of the Congo (DRC). Aim: This study aimed to assess the knowledge and behaviours of university students...

Open access Research Article 10.9734/JPRI/2017/31848