Background: Pregnancy is associated with physiological changes in haemostasis that may vary across gestation. Aims: To assess prothrombin time (PT), activated partial thromboplastin time (aPTT), and platelet count across the three trimesters of pregnancy and compare these paramet...
Open access
Research Article10.9734/ibrr/2026/v17i4401
Background: Storage of whole blood is accompanied by biochemical and cellular changes that may alter soluble adhesion molecules. This study evaluated serum concentrations of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), and P-selectin dur...
Open access
Research Article10.9734/ibrr/2026/v17i4400
Sickle cell disease is a systemic vasculopathy in which intravascular haemolysis, endothelial activation, leukocyte and platelet recruitment, and coagulation activation operate as a single self-reinforcing process now commonly described as thromboinflammation. Most of the mechani...
Open access
Research Article10.9734/ibrr/2026/v17i4399
Background: Evidence concerning the relationship of ABO blood groups with metabolic markers remains inconsistent, particularly among apparently healthy young adults. Aim: To determine the relationship between ABO blood groups, fasting blood glucose, and serum uric acid levels amo...
Open access
Research Article10.9734/ibrr/2026/v17i4398
Background: Lassa fever is a viral haemorrhagic illness endemic to Nigeria and other West African countries. Severe cases are often associated with abnormal coagulation and impaired platelet function. Objective: This study primarily assessed coagulation parameters and examined th...
Open access
Research Article10.9734/ibrr/2026/v17i4397
Inflammation is inseparable from blood-cell biology: circulating cells detect inflammatory cues, bone-marrow progenitors alter lineage output, erythroid iron supply is actively restricted, and haemostatic pathways can be recruited as components of host defence. Yet the expression...
Open access
Research Article10.9734/ibrr/2026/v17i4396
Background: Routine haematological and biochemical indices support monitoring of adults with HIV, but geographical variation in Rivers State is insufficiently described. Aims: To compare blood count indices, inflammatory cell ratios, biochemical parameters and physical indicators...
Open access
Research Article10.9734/ibrr/2026/v17i4395
Background: Nigeria is home to more than two million people living with HIV, yet it remains underrepresented in HIV vaccine trials. Peripheral blood mononuclear cells (PBMCs) are vital for assessing vaccine-induced immunity; however, biobanking in resource-limited settings presen...
Open access
Research Article10.9734/ibrr/2026/v17i4394
Background: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder characterised by persistent synovial inflammation and progressive joint damage. Aim: This study assessed selected autoimmune and inflammatory biomarkers among individuals with RA in Port Harcourt,...
Open access
Research Article10.9734/ibrr/2026/v17i4393
Background: Male reproductive dysfunction is increasingly relevant in chronic anaemias as survival into adulthood has improved in β-thalassaemia and sickle cell disease, while iron-deficiency anaemia remains globally common. Impaired fertility arises through hypoxia, oxidative st...
Open access
Research Article10.9734/ibrr/2026/v17i4392