Epithelial Mesenchymal Transition (EMT) is a crucial process in embryogenesis, however it also plays an important role in pathologies including inflammation, wound healing and cancer. EMT is a determining step in cancer metastasis as tumour cells utilise the process of EMT for in...
Open access
Research Article10.9734/jammr/2022/v34i431288
Background: Oral Squamous Cell Carcinoma (OSCC) is the most common malignancies which accounts for 90% of oral cancer worldwide. The 5 year survival rate of OSCC is not more than 60% due to tumor metastasis and subsequent recurrence. Aim: To compare the gene expression of ITG β-1...
Open access
Research Article10.9734/jpri/2021/v33i44B32653
Background: Oral squamous cell cancer (OSCC) develops as a result of the accumulation of many genetic mutations that are influenced by genetic predisposition. Upon acquisition of genetic predisposition, the precancerous cells will transform into malignant cells culminating into c...
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Research Article10.9734/jpri/2021/v33i44A32605
Background: Lung cancer is considered as one of the most common causes for cancer-related death globally. Carica papaya is one of the most well-known traditional medicines to treat diseases, and is also known to treat cancer and help in cancer prevention. The study investigates t...
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Research Article10.9734/jpri/2022/v34i5B35410
Introduction: Glyphosate, an N-(phosphonomethyl) glycine is the active ingredient in the pervasive herbicide, Monsanto Roundup. It is widely used herbicide worldwide to eliminate unwanted plants both on agricultural and non agricultural landscapes. Glyphosate is used in different...
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Research Article10.9734/jpri/2022/v34i5B35417
Introduction: Sida acuta is known as common wireweed, and has a pantropical distribution. Antioxidants fight against free radicals and prevent a variety of diseases. Anti Inflammatory reaction is the ability of a substance to reduce swelling or inflammation. Antidiabetic substanc...
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Research Article10.9734/jpri/2021/v33i64A35306
Background: Medicinal herbs have been widely used in therapeutic applications for various diseases in today’s world. These herbs are used by village folk medicine, but without scientific evidence. Corchorus olitorius, also known as jute mallow is a herb that possesses many curin...
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Research Article10.9734/jpri/2021/v33i64A35719
Background: Cancer is uncontrolled division and proliferation of abnormal cells in the body. Nowadays, therapeutic Treatment of cancer has become a great clinical challenge and alternative medicines are being extensively studied to cure cancer. Aegle marmelos is one such plant Wh...
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Research Article10.9734/jpri/2021/v33i62A35669
Introduction: Cayratia trifolia is a plant belonging to the family Vitaceae and genus Cayratia. Anti-inflammatory activity is the property of a substance or treatment that reduces inflammation or swelling. Antioxidants are defined as substances that delay or inhibit oxidative dam...
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Research Article10.9734/jpri/2021/v33i61B35496
Background: Lung cancer has the highest mortality rate and highest rate of metastasis. Kabasura kudineer was used widely during the Covid period. The aim of the study is to find the effect of kabasura kudineer extract on inhibitory kappa B kinase beta and mTOR mRNA complex expres...
Open access
Research Article10.9734/jpri/2021/v33i61A35675
Background: Andrographis echioides is a medicinal herb, used in the treatment of various diseases. It has potential antioxidant properties. The present study plan is to find a novel herbal antidote for oxidative stress from Andrographis echioides. Objective: The aim of the cu...
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Research Article10.9734/jpri/2021/v33i61A35677
Background: Aegle marmelos belong to the family rutaceae. It is commonly known as Bael. It is used in traditional medicine, as it has antidiarrheal, antimicrobial, antiviral, radio-protective, anticancer, chemo-preventive properties which are of great medicinal use. Liver cancer...
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Research Article10.9734/jpri/2021/v33i60B35093
Background and Aim: Acalypha indica is a weedy, short lived and monoecious plant. It has an antioxidant effect and it must be implemented to control the disease where free radicals are involved. Acalypha plant is useful for the bronchitis, pneumonia, pulmonary tuberculosis patien...
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Research Article10.9734/jpri/2021/v33i60B34882
Background and Aim: A.marmelos is commonly called as Bael and is used as a medicinal plant mostly in the Ayurveda. Bael has the property of gastrointestinal effect. Bael phytochemicals are radioprotective, chemoprotective and it has efficacious properties in the treatment of canc...
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Research Article10.9734/jpri/2021/v33i60B34884
Introduction: Citrullus colocynthis has many pharmacological, biological, and therapeutic properties making it a very important medicinal plant. The cucurbitacin produced/derived from the plant play an important role in anticancer activities. The retinoblastoma Y-79 cell lines ar...
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Research Article10.9734/jpri/2021/v33i59B34433
Introduction: Inflammation is said to be the response of the body to an injury. It is a body defence reaction to reduce or eliminate the spread of injurious agents. It is essential that steps should be taken to introduce new medicinal plants and to develop cheaper, effective and...
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Research Article10.9734/jpri/2021/v33i58A34119
Background: Aegle marmelos (AE) is a medicinal plant that comes under the rutaceae family and the plant was used in the past for treating many diseases and illness symptoms. The plant has many effects such as anti-diarrhoeal, antimicrobial, antiviral, radioprotective, anticancer,...
Open access
Research Article10.9734/jpri/2021/v33i58B34209
Background: Tecoma stans is an important medicinal plant. The major bioactive compounds like alkaloids, phenols, terpenoids, glycosides, flavonoids and saponins had been isolated from this plant. The leaves bark and roots contain biologically active chemicals, and extracts from t...
Open access
Research Article10.9734/jpri/2021/v33i57A33989
Citrullus colocynthis is a traditional medicinal plant that belongs to the cucurbitaceae family. The extract of the fruit is rich in therapeutic phytochemicals. Lung cancer is a disease with high mortality and morbidity rates. Recently the research has been focused on herbal medi...
Open access
Research Article10.9734/jpri/2021/v33i57B34033
Introduction: Kaempferia galanga is a medicinal plant belonging to the family Zingiberaceae: ginger family. It is treated as a folk traditional herb. Anti Inflammatory property refers to the ability of a substance to reduce inflammation or any of its 5 cardinal signs. Aim: To ass...
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Research Article10.9734/jpri/2021/v33i47B33146
Introduction: Cancer is the second leading cause of death all over the world where among all types of cancer breast cancer is said to be the leading cancer followed by lung cancer. The aim of this study is to find the regulation of chloride intracellular channel protein 1 and cas...
Open access
Research Article10.9734/jpri/2021/v33i47B33158
Background: Aegle marmelos commonly known as Bael is a herbal plant. Itis from a family called Rutaceae. It has many medicinal uses: anti-diarrheal, anti- microbial, anti-viral, anti-cancer, chemo-preventive, Ulcer healing and many others. Aim: To study the effect of Aegle marmel...
Open access
Research Article10.9734/jpri/2021/v33i47B33159
Background: Kabasura kudineer is widely known for its anticancer efficiency. Kabasura kudineer is a customary formulation used by siddha practitioners for effectively managing common respiratory illness. Herbal medicines are acknowledged as a great approach to lung cancer therapy...
Open access
Research Article10.9734/jpri/2021/v33i47B33167
This study will help in determining which molecules participate in the ulceration with an integrated approach combining external and internal factors. Recurrent aphthous stomatitis (RAS) is a common condition affecting the oral mucosa. Clinically it is manifested through recurren...
Open access
Research Article10.9734/jpri/2021/v33i47A33003
Potentially malignant disorders are “the risk of malignancy being present in a lesion or condition either at the time of initial diagnosis or at a future date” include mainly leukoplakia, erythroplakia, oral lichen planus, oral submucous fibrosis. Biomarkers were of immense help...
Open access
Research Article10.9734/jpri/2020/v32i1830687
Aim: To analyse the preliminary phytochemical, antioxidant, anti-cholesterol potential of aqueous extract of Ferula asafoetida. Background: Hyperlipidemia is considered as one of the leading causes behind the occurrence of deadly disorders like diabetes, cardiovascular diseases,...
Open access
Research Article10.9734/jpri/2022/v34i6A35414
Background: Trigonella foenum-graecum is one of the commonly used herbs in food. Moringa oleifera is a source of food, accommodation and conventional medicine for many peoples in the developing countriesThe seeds of both the plants were explored for antidiabetic potential. Method...
Open access
Research Article10.9734/jpri/2022/v34i3B35392
Introduction: A condition in which the body’s ability gets impaired to process blood glucose level is called diabetes, otherwise known as blood sugar. It ranked sixteenth among leading causes of death around the globe. There are estimated 72.96 million cases diagnosed with diabet...
Open access
Research Article10.9734/jpri/2021/v33i62A35518
Background: Glyphosate is the most enormously used broad spectrum herbicide in the world. Current assessment of carcinogenic capability of glyphosate-based herbicides by various regional, national, and international agencies have endangered the controversy. Antioxidant enzymes ar...
Open access
Research Article10.9734/jpri/2021/v33i61A35453
Background: Several plant extracts and herbs have been used for treating and prevention of cardiovascular diseases hypertension, angina pectoris, congestive heart failure, atherosclerosis, cerebral and venous insufficiency and arrhythmia. Similarly, aqueous extracts of Citrus aur...
Open access
Research Article10.9734/jpri/2021/v33i60B34820
Background: Gout is an inflammatory joint disease that elevates the uric acid levels in blood that triggers the formation of urate crystals in the joint,especially since the past 50 years. Xanthine oxidase catalyses oxidative hydroxylation of hypoxanthine to Xanthine to uric acid...
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Research Article10.9734/jpri/2021/v33i60B34799
Introduction: Medicinal plants are chief antidotes for numerous diseases and have been used since time immemorial. Sweet flag’s (Acorus calamus) presence is in Ayurveda and belongs to the genus Acorus L. of the family Acoraceae and is widely distributed in temperate to sub temper...
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Research Article10.9734/jpri/2021/v33i59B34401
Background: Stevia rebaudiana is a shrub-like plant that belongs to the sunflower family and is commonly referred as stevia.It is 1000 times sweeter than sugar even at a very low concentration. Xanthine oxidase is an enzyme that generates oxygen species and catalyzes the producti...
Open access
Research Article10.9734/jpri/2021/v33i59B34384
Background: Glyphosate is a broad spectrum herbicide and desiccant. Diabetes is a group of metabolic diseases resulting due to deficiency in insulin secretion. Chronic hyperglycemia will lead to long term damage and failure of different organs like eyes, kidneys, nerves etc. Liv...
Open access
Research Article10.9734/jpri/2021/v33i59B34389
Background: Ferula asafoetida is a dried latex that is exuded from rhizome or taproot species. Organosulfides are primarily responsible for flavour and odour of asafoetida.Ferula asafoetida is a natural medicine good for asthma and bronchitis. is also used to relieve stomach gas,...
Open access
Research Article10.9734/jpri/2021/v33i57B34042
Introduction: Myristica fragrans is an important commercial plant used for spices. The plant has been traditionally used as an anticancer, anti inflammatory, antioxidant, sedative hypnotics and antimicrobial agent. Plants have played an important role in maintaining human health...
Open access
Research Article10.9734/jpri/2021/v33i57B34379
Background: Punica granatum belongs to the family punicaceae. Pomegranate has a reservoir of secondary metabolites which possess free radical scavenging activity. Pomegranate has high antioxidants content, which helps in the delayed progress of atherosclerosis, cancer and ageing....
Open access
Research Article10.9734/jpri/2021/v33i55B33843
Background: Diabetes is a rapidly growing metabolic disorder of the present generation. Uncontrolled diabetes leads to various complications which in turn affects the vascular system, neuropathy,and more. Medicinal plants are always a good source of drug equivalent currently pre...
Open access
Research Article10.9734/jpri/2022/v34i5B35409
Background: Genus Allium produces compounds of sulfur which is an important component for medical use. Studies have The Allium species and their extracts have the effect on cardiovascular disease risk factor. Both Allium cepa and Allium sativum are used as one of the spices in fo...
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Research Article10.9734/jpri/2021/v33i61A35457
Introduction: Ethanolic extracts of Alternanthera sessilis and Moringa oleifera were screened for the presence of different classes of phytochemicals. The phytochemical screening revealed the presence of amino acids, flavonoids, alkaloids, terpenoids, sapponents and steroids.Gout...
Open access
Research Article10.9734/jpri/2021/v33i60B34975
Background: Acalypha indica Linn. is a weed plant found in shady wetlands. It is commonly called as kuppai meni in Tamil, belonging to the family Euphorbiaceae. It is found to be one of the greatest Indian plants with anti-venom, antibacterial, antiviral and antimicrobial propert...
Open access
Research Article10.9734/jpri/2021/v33i60B34918
Introduction: Various parts of the tree Moringa oleifera Lam belonging to the Moringceae family are used extensively by the Indians as a major food constituent and also as herbal medicine. The dried seeds are used as a hypolipidemic agent for patients who suffer from obesity....
Open access
Research Article10.9734/jpri/2021/v33i60B34934