In-vitro Antioxidant and Antidiabetic Properties of Corchorus olitorius Leaves and Seed Ethanol Extract

Abstract

Background: Medicinal herbs have been widely used in therapeutic applications for various diseases in today’s world. These herbs are used by village folk medicine, but without scientific evidence.  Corchorus olitorius, also known as jute mallow is a herb that possesses many curing effects like pain, fever and many other diseases like cystitis and tumour etc. Objective: The objective of the study was to elucidate the effects of corchorus olitorius as antioxidant and antidiabetic. Materials and Methods: In Vitro Evaluation of antidiabetic and antioxidant properties were conducted using various tests. Alpha - amylase inhibitory activity and  alpha glucosidase inhibitory activity for antidiabetic activity and DPPH free radical scavenging assay for antioxidant property was performed. The results were compared with standard metformin and aspirin respectively. Results: Results showed a dose dependent increase in alpha amylase inhibitory activity with concentration ranging from 100-500 micro/ml. Results showed a dose dependent increase in alpha glucosidase inhibitory activity with concentration ranging from 100-500 micro/ml. Results showed a dose dependent increase in DPPH free radical scavenging activity with concentration ranging from 100-500 micro/ml. Conclusion: The results showed an innovative finding that ethanolic seed extract of corchorus olitorius has great potential as antidiabetic and antioxidant property which can be used as novel innovative natural medication in the medical field rather than using any artificial synthetic drug which causes many other side-effects like allopathic drugs.