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E. O. Nwachuku

Publications (31)

Assessment of the Effects of Some Herbal Supplements on Some Inflammatory and Hepatic Markers of Cyanide– Induced Hyperthyroid Female Albino Rats

E. O. Nwachuku, B. N. C. Onuoha, D. G. Tamuno-Emine & I. Elekima · International Research Journal of Gastroenterology and Hepatology · 2022

Aim: To assess the effects of some herbal supplements on some inflammatory and hepatic markers of cyanide – induced hyperthyroid female Albino Rats. Study Design:  Experimental study. Place and Duration of Study: Department of Animal and Environmental Sciences, Rivers State Unive...

Open access Research Article

Anti-tumour Potential of Punica granatum (Pomegranate) Seed in Testosterone-induced Benign Prostate Hyperplastic Wistar Albino Rats

U. A. Obisike, E. O. Nwachuku & N. Boisa · Asian Journal of Research and Reports in Urology · 2021

Aim: The aim of this study was to assess the anti-tumour potentials of Punica granatum (Pomegranate) seed in testosterone-induced Benign Prostate Hyperplastic Wistar albino Rats. Study Design: This study is an experimental study. Place and Duration of Study: The experimental aspe...

Open access Research Article

Assessment of Renoprotective Effect of Pentaclethra macrophylla Seed (Ugba) against Mercury Induced Acute Kidney Injury in Male Albino Rats

J. D. Nwahiri, E. O. Nwachuku, D. G. Tamuno-Emine & E. S. Bartimaeus · International Journal of Advances in Nephrology Research · 2021

Aim: The aim of this study was to assess the renoprotective effect of Pentaclethra macrophylla seed (Ugba) against Mercury induced acute kidney injury in male Albino Rats. Study Design:  This is an interventional study. Place and Duration of Study: Department of Animal and Enviro...

Open access Research Article

Evaluation of the effect of Jathropha interrigima (Euphorbiaceae) on Hepatic Function of Male Albino Wistar Rats Exposed to Lead

M. J. Andy-Nwokocha, E. O. Nwachuku, E. S. Bartimaeus & C. C. Obunwo · International Research Journal of Gastroenterology and Hepatology · 2021

Aim: The aim of the study was to evaluate the effect of Jathropha interrigima on hepatic function of male Albino Wistar rats exposed to lead. Study Design: The study is an experimental study. Place and Duration of Study: Department of Animal and Environmental Biology, Rivers Stat...

Open access Research Article

Evaluation of the Effect of Jatropha integerrima (Euphorbiaceae) on the renal Function of Male Albino Wistar Rats Exposed to Chromium

M. J. Andy-Nwokocha, E. O. Nwachuku, E. S. Bartimaeus & C. C. Obunwo · Journal of Complementary and Alternative Medical Research · 2021

Aim: The aim of the study was to evaluate the effect of Jathropha interrigima on renal function of male Albino Wistar rats exposed to chromium. Study Design:  The study is an experimental study. Place and Duration of Study: Department of Animal and Environmental Biology, Rivers S...

Open access Research Article 10.9734/jocamr/2021/v14i130237

Assessment of the Antioxidant Potential of Hypoestes rosea Leaf in Lead-acetate-induced Albino Rats

F. K. Uwikor, E. O. Nwachuku, F. Igwe & E. S. Bartimaeus · Journal of Complementary and Alternative Medical Research · 2020

Hypoestes rosea has been used as a traditional medicine in the Niger delta for dysfunction of the endocrine system. However, there has been no known study on the effects of hypoestes rosea on oxidative stress. In this study we evaluated the effect of aqueous extract of Hypoestes...

Open access Research Article 10.9734/jocamr/2020/v9i130135

Therapeutic Effects of the Anti-diabetic Polyherbal Drug Diawell in Combination with Metformin on Liver and Lipid Parameters in Type 2 Diabetic Rats

O. N. Briggs, E. O. Nwachuku, H. Brown & K. N. Elechi-Amadi · Journal of Complementary and Alternative Medical Research · 2019

Type 2 diabetes is one of the most important diseases worldwide. It affects several organ systems including the liver and lipid metabolism. Many herbal formulations have shown anti-diabetic potential, however, their safety and efficacy remain a debate in the medical community. Ai...

Open access Research Article 10.9734/jocamr/2019/v8i230118

Antidiabetic and Antioxidant Effects of the Polyherbal Drug Glucoblock and Glibenclamide in Type 2 Diabetic Rats

O. N. Briggs, E. O. Nwachuku, E. S. Bartimaeus, D. Tamuno-Emine, K. N. Elechi-Amadi & N. Nsirim · Journal of Advances in Medical and Pharmaceutical Sciences · 2019

The increased prevalence of diabetes, and the huge disease burden on patients has led to an increase in the use of complementary and alternative medicine in diabetes treatment and management. Aim: This study evaluates the antidiabetic and antioxidant effects of the polyherbal cap...

Open access Research Article 10.9734/jamps/2019/v21i230129

Biochemical and Oxidative Changes in High Fat Diet/Streptozotocin-induced Diabetic Rats Treated with Metformin and the Polyherbal Diawell

O. N. Briggs, E. O. Nwachuku, D. Tamuno-Emine, N. Nsirim & K. N. Elechi-Amadi · Journal of Complementary and Alternative Medical Research · 2019

Diabetes mellitus is an epidemic, with a huge disease burden on the patients. This has led to an increase in the use of herbal remedies and combination therapies to reduce this burden. Aim: This study evaluates the biochemical and oxidative changes in type 2 diabetic rats, treate...

Open access Research Article 10.9734/jocamr/2019/v7i430107

Effects of the Interation of Metformin and Vernonia amygdalina (Bitter Leaf) On Steptozotocin-Induced Diabetic Rats

A. T. Oluwayemi, E. O. Nwachuku & B. Holy · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2018

The effects of Vernonia amygdalina and metformin in lowering glucose in streptozotocin-induced diabetic rats were evaluated. A total of 120 Wistar albino males and females rats weighing approximately 200 g were used for the study. Diabetes was induced in the rats using 50 mg/kg o...

Open access Research Article 10.9734/ajbgmb/2018/v1i227494

Chronic Toxicological Effect of 2, 2-dichlorovinyl Dimethyl Phosphate (Sniper) on Some Reproductive and Thyroid Hormones of New Zealand white Rabbits

K. I. Green, C. C. Ozoemena & E. O. Nwachuku · International Journal of Research and Reports in Gynaecology · 2022

Aim: To assess the chronic toxicological effect of 2, 2-dichlorovinyl dimethyl phosphate (DDVP, with trade name - sniper) on some reproductive and thyroid hormones of New Zealand white Rabbits. Study Design: An experimental study. Place and Duration of Study: Department of Biolog...

Open access Research Article

Evaluation of 2, 2-dichlorovinyl Dimethyl Phosphate (Sniper) Induced Hepatotoxicity and Oxidative Stress in New Zealand White Rabbits

C. C. Ozoemena, F. U. Igwe, E. O. Nwachuku & E. S. Bartimaeus · International Research Journal of Gastroenterology and Hepatology · 2021

Aim: The aim of this study was to evaluate chronic hepatotoxicity and oxidative stress induced by 2, 2-dichlorovinyl dimethyl phosphate (Sniper) in New Zealand white rabbits. Study Design:  This is an experimental study. Place and Duration of Study: Department of Biological Scien...

Open access Research Article

Antioxidant Potentials of Pentaclethra macrophylla Seed (Ugba) on Mercury Toxicity Induced Hepatic, Renal and Testicular Oxidative Stress in Male Albino Rats

J. D. Nwahiri, D. G. Tamuno-Emine, E. O. Nwachuku & E. S. Bartimaeus · Journal of Complementary and Alternative Medical Research · 2021

Aim: This study aimed to evaluate the antioxidant potentials of Pentaclethra macrophylla seed (Ugba) on mercury-induced hepatic, renal and testicular oxidative stress in male Albino Rats. Study Design: This study is an experimental study. Place and Duration of Study: Department o...

Open access Research Article 10.9734/jocamr/2021/v16i430305

Pomegranate Seed Extract: A Strong Antioxidant against Benign Prostatic Hyperplasia Induced Oxidative Stress in Albino Wistar Rats

U. A. Obisike, N. Boisa & E. O. Nwachuku · Journal of Cancer and Tumor International · 2021

Aim: The aim of this study was to assess the antioxidant properties of ethanolic and aqueous extracts of Punica granatum (Pomegranate) seed in testosterone induced benign prostate hyperplastic albino Wistar rats. Study design: This study is an interventional study. Place and Dura...

Open access Research Article 10.9734/jcti/2021/v11i430160

Effect of Emzor Omega 3 Fish Oil on Beta Cell Function of Streptozotocin Induced Diabetic Rats

U. J. O. Orji, H. Brown, E. O. Nwachuku & N. Boisa · Asian Journal of Research and Reports in Endocrinology · 2021

Aim: The aim of this study was to evaluate the effect of Emzor Omega 3 Fish Oil on Beta Cell function of Streptozotocin Induced Diabetic Rats. Study Design:  An experimental study. Place and Duration of Study:  Animal House, Department of Applied and Environmental Biology, Rivers...

Open access Research Article

Antioxidant Potentials of Blue Whiting Fish (Micromesistus poutassous) Oil Extracts in Streptozotocin Induced Diabetic Rats

U. J. O. Orji, H. Brown, E. O. Nwachuku & N. Boisa · Journal of Complementary and Alternative Medical Research · 2021

Aim: The aim of this study was to assess the antioxidant potentials of Blue Whiting Fish (Micromesistus poutassous) oil extracts in streptozotocin induced diabetic rats. Study Design:  An experimental study. Place and Duration of Study:  Animal House, Department of Applied and En...

Open access Research Article 10.9734/jocamr/2021/v14i430251

Effect of Calamari Oil on Lipid Profile of Streptozotocin Induced Diabetic Rats

U. J. O. Orji, H. Brown, E. O. Nwachuku & N. Boisa · Cardiology and Angiology: An International Journal · 2021

Aim: The aim of this study was to assess the effect of Calamari Oil on lipid profile levels in diabetes streptozotocin induced diabetic Rats. Study design: An experimental study. Place and duration of study: Animal House, Department of Applied and Environmental Biology, Rivers St...

Open access Research Article 10.9734/ca/2021/v10i330171

Gene Frequencies of Human Platelet Alloantigens in Major Ethnic Groups in Rivers-State, Nigeria

J. E. Wenah-Emmanuel, E. M. Eze, E. O. Nwachuku, E. Wenah & Z. A. Jeremiah · International Journal of Research and Reports in Hematology · 2021

Aim: The aim of this study was to evaluate gene frequencies of human platelet alloantigens among major ethnic groups in Rivers-State, Nigeria. Study Design: A cross-sectional study. Place and Duration of Study: Rivers State University Medical Centre, Port Harcourt, Safety Molecul...

Open access Research Article

Assessment of Gene Frequencies of Human Platelet Alloantigens in Rivers-State, Nigeria Based on ABO/Rhesus Blood Groups Distribution

J. E. Wenah-Emmanuel, E. M. Eze, E. O. Nwachuku, E. Wenah & Z. A. Jeremiah · International Blood Research & Reviews · 2021

Aim: The aim of this study was to assess the Gene Frequencies of Human Platelet Alloantigens in Rivers-State, Nigeria based on ABO/Rhesus blood groups distribution Study Design:   A randomized controlled trial. Place and Duration of Study: Rivers State University Medical Centre,...

Open access Research Article 10.9734/ibrr/2021/v12i330152

Evaluation of the Effect of Some Marketed Herbal Cosmetics in Port Harcourt on Renal Parameters of Rabbits

I. N. Thompson, E. S. Bartimaeus, E. O. Nwachuku, H. Brown & E. S. Agoro · European Journal of Medicinal Plants · 2021

Aim: The aim of this study was to evaluate the effects of three commonly marketed herbal cosmetics in Port Harcourt on the renal parameters in rabbits. Study Design:  This study is an experimental study. Place and Duration of Study: This study was carried out at Animal House, App...

Open access Research Article 10.9734/ejmp/2021/v32i230375

Assessment of Some Heavy Metals and Iron Parameters amongst Dumpsite Scavengers in Port Harcourt, Nigeria

A. S. Godwin, H. Brown & E. O. Nwachuku · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aim: The aim of the study was to determine the levels of some heavy metals, namely Cadmium (Cd), Lead (Pd), and Iron (Fe) in waste scavengers in port-Harcourt, Nigeria Study Design:  This study is a cross-sectional observational study. Place and Duration of Study: This study was...

Open access Research Article 10.9734/jamps/2020/v22i1130203

Evaluation of Antioxidant Potentials of Ocimum gratissimum and Xylopia aethiopica in Alcohol- Induced Hepatotoxic Albino Rats

N. C. Chuks-Oguine, E. S. Bartimaeus & E. O. Nwachuku · Journal of Complementary and Alternative Medical Research · 2020

Aims: This study evaluated the antioxidant potentials of Ocimum gratissimum and Xylopia aethiopica on Alcohol-induced Hepatotoxicity in Albino rats. Study Design: The study is an experimental case-controlled study. Place and Duration of Study: This study was conducted at the Depa...

Open access Research Article 10.9734/jocamr/2020/v10i230158

Antiproliferative Potentials of Zingiber officinale in Testosterone Induced Prostate Hyperplastic Albino Wister Rats

U. A. Obisike, N. Boisa, E. O. Nwachuku & N. Nduka · International Research Journal of Oncology · 2020

Aims: The present study evaluated the anti-proliferative potential of Zingiber officinale - Zo (Ginger) rhizome and Dutasteride (Avodart) singly and in combination on testosterone propionate (TP) induced benign prostatic hyperplastic (BPH) male albino wistar rats. Study Design: T...

Open access Research Article

Assessment of the Antioxidant Potential of Hypoestes rosea Leafin Streptozotocin-induced Diabetic Albino Rats

P. E. Africa, D. G. Tamuno Emine, E. O. Nwachuku & E. S. Bartimaeus · Journal of Complementary and Alternative Medical Research · 2020

Aims: The present paper was to investigate possible antioxidant actions of Hypoestes rosea leaf extracts in streptozotocin-induced diabetes mellitus in rats. Study Design:  This study is an interventional study. Place and Duration of Study: This study was conducted in the animal...

Open access Research Article 10.9734/jocamr/2020/v9i430149

Assessment of Antioxidant Effects of Aqueous and Ethanolic Extracts of Zingiber officinale Rhizome in Testosterone Induced Benign Prostatic Hyperplasia Rat Model

U. A. Obisike, N. Boisa, E. O. Nwachuku & N. Nduka · Journal of Complementary and Alternative Medical Research · 2019

Aims: To assess the antioxidant effects of the aqueous and ethanolic extracts of Ginger rhizome in testosterone induced prostate hyperplasic male rats. Study Design: The study was a cross-sectional study. Place and Duration of Study: The experimental aspect of this study was cond...

Open access Research Article 10.9734/jocamr/2019/v8i230120

Evaluation of Lipid Profile and Some Renal Parameters in Some Selected Ethnic Population with Fat-mass and Obesity-associated Gene (FTO) Variants in Niger Delta, Nigeria

N. O. Ekpete, I. Elekima, H. Brown & E. O. Nwachuku · Cardiology and Angiology: An International Journal · 2022

Aim: To evaluate lipid profile and some renal parameters in some selected ethnic population with fat-mass and obesity-associated gene (FTO) variants in Niger Delta, Nigeria. Study Design:  Case-controlled observational study. Place and Duration of Study: Federal Medical Centre, A...

Open access Research Article 10.9734/ca/2022/v11i430204

Obesity and Type 2 Diabetes Markers and Their Association with Fat-mass and Obesity-associated Gene (FTO) Variants in Some Selected Ethnic Populations in Niger Delta, Nigeria

N. O. Ekpete, H. Brown, I. Elekima & E. O. Nwachuku · Asian Journal of Research and Reports in Endocrinology · 2022

Aim: To assess the levels of some glycemic parameters and their association with fat-mass and obesity-associated gene (FTO) variants in some selected ethnic populations in Niger Delta, Nigeria. Study Design:  Case-controlled observational study. Place and Duration of Study: Feder...

Open access Research Article

Therapeutic Evaluation of Selected Herbal Supplements on Thyroid Hormones of Cyanide – Induced Hyperthyroidism in Female Albino Rats

B. N. C. Onuoha, I. Elekima, D. G. Tamuno-Emine & E. O. Nwachuku · Journal of Complementary and Alternative Medical Research · 2022

Aim: To evaluate the therapeutic effect of some herbal supplements on thyroid hormones of cyanide – induced hyperthyroidism in Female Albino Rats. Study Design:  Experimental study. Place and Duration of Study: Department of Animal and Environmental Biology,                      ...

Open access Research Article 10.9734/jocamr/2022/v17i330334

Assessment of Chronic Toxicological Effects of 2, 2-Dichlorovinyl Dimethyl Phosphate (Sniper) on the Kidneys of New Zealand White Rabbits

C. C. Ozoemena, E. S. Bartimaeus, F. U. Igwe & E. O. Nwachuku · International Journal of Advances in Nephrology Research · 2021

Aim: The aim of this study was to assess the chronic toxicological effects of 2, 2-dichlorovinyl dimethyl phosphate (Sniper) on the kidneys of New Zealand white Rabbits. Study Design:  This is an experimental study. Place and Duration of Study: Department of Biological Science, R...

Open access Research Article

Assessment of Testosterone Levels and Sperm Motility Variables of Mercury Toxicity Induced Male Albino Rats Treated with Pentaclethra macrophylla Seed (Ugba)

J. D. Nwahiri, C. C. Ozoemena, B. N. Okolonkwo, D. G. Tamuno-Emine, E. O. Nwachuku & E. S. Bartimaeus · Asian Journal of Research and Reports in Endocrinology · 2023

Aim: To assess testosterone levels and sperm motility variables of mercury toxicity induced male Albino Rats treated with Pentaclethra macrophylla seed (Ugba). Study Design: An experimental study. Place and Duration of Study: Department of Animal and Environmental Biology Animal...

Open access Research Article

Variations in Fat-mass and Obesity-associated (FTO) Genes and Allelic Distribution in Some Selected Ethnic Populations in Niger Delta, Nigeria

N. O. Ekpete, I. Elekima, H. Brown, E. E. Osaji, B. O. Igbinaduwa, P. T. Nnanna & E. O. Nwachuku · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2023

Aim: To evaluate variations in FTO genes and allelic distribution in some ethnic populations in Niger Delta, Nigeria. Study Design:  Case-controlled observational study. Place and Duration of Study: Federal Medical Centre, Asaba, Delta State and Safety Molecular Pathology Laborat...

Open access Research Article 10.9734/ajbgmb/2023/v13i2290