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C. O. Ujowundu

Publications (17)

Ecotoxicological Impact of Sub-lethal Concentrations of Glyphosate–based Herbicide on Juvenile Clarias gariepinus

C. O. Ujowundu, D. M. Koloseke, N. O. Uba, J. J. Achilike, H. D. Ogbuagu & E. A. Ubuoh · Journal of Advances in Medicine and Medical Research · 2017

The presence of pesticides in both aquatic and terrestrial ecosystems has become an important issue globally. This study determined the possibility of bioaccumulation of glyphosate, the active compound of Roundup pesticides in muscle tissues of juvenile Catfish (Clarias gariepinu...

Open access Research Article 10.9734/JAMMR/2017/34374

Lead-induced Oxidative Stress and Chemoprotective Role of Dietary Supplements on Wistar Albino Rats

C. O. Ujowundu, G. N. Okwu, J. J. Achilike, L. A. Nwaogu, A. C. Ene & C. I. Iheme · Annual Research & Review in Biology · 2017

The heavy metal lead (Pb) is a common environmental pollutant with widespread distribution, and oxidative stress has been implicated in the pathogenesis of its toxicity. The ameliorative effect of nutritional contents of palm oil and cod liver oil (dietary supplements) following...

Open access Research Article 10.9734/ARRB/2017/33167

Free Radicals Scavenging and Neuroprotective Effects of Ethanolic Leaf Extract of Combretum zenkeri Leaf

C. O. Ujowundu, C. U. Ogbonna, G. N. Okwu & C. S. AIisi · Annual Research & Review in Biology · 2014

Combretum zenkeri is a small tree found in the tropical West Africa that has been applied by locals in the treatment of arthritic and other inflammatory diseases. This study investigated the free radical scavenging activities of ethanolic leaf extract of C. zenkeri against nitric...

Open access Research Article 10.9734/ARRB/2015/14039

Hepatoprotective Effects of Crude Extracts of Tomato and Onion in Rats Exposed to Locally Processed Beef

C. O. Ujowundu, H. N. Okoye, R. N. Nwaoguikpe, D. C. Belonwu, K. O. Igwe & F. N. Ujowundu · International Journal of Biochemistry Research & Review · 2014

This study was carried out to examine the hepatoprotective effect of ethylacetate extract of tomatoes and methanol extract of onions on the biochemical changes induced by feed formulated with 15% roasted beef and 85% rats pellets. Doses of 500 mg/kg body weight of both extracts w...

Open access Research Article 10.9734/IJBCRR/2014/7353

Procarcinogens: Polycyclic Aromatic Hydrocarbons and Heavy Metal Content in Some Locally Processed Foods in South Eastern Nigeria

C. O. Ujowundu, K. L. Ihekweazu, C. S Alisi, F. N. Ujowundu & C. U. Igwe · Current Journal of Applied Science and Technology · 2013

This study investigated the presence of polycyclic aromatic hydrocarbons (PAHs) and heavy metals in commonly consumed roasted meats and smoked fish in Owerri, Imo State, Nigeria. The processed foods were grouped as; freshly processed- 6 to 12 hours heat/flame/smoke exposure and l...

Open access Research Article 10.9734/BJAST/2014/4668

Effect of Gas Flaring on the Phytochemical and Nutritional Composition of Treculia africana and Vigna subterranean

C. O. Ujowundu, L. A. Nwaogu, F. N. Ujowundu & D. C. Belonwu · Biotechnology Journal International · 2013

Aims: The effect of petroleum exploration and exploitation activities on the phytochemical and nutritional composition of African breadfruit (Treculia africana) and Bambara groundnuts (Vigna subterranean) harvested from polluted and unpolluted environment were studied. Study Desi...

Open access Research Article 10.9734/BBJ/2013/3033

Biochemical Studies on the Amelioration of Petroleum Product Intoxication with Indigenous Plants

C. O. Ujowundu, F. N. Kalu, C. U. Igwe, N. C. Agha & K. O. Igwe · International Journal of Biochemistry Research & Review · 2012

The effect of Gongronema latifolium and Ocimum gratissimum supplemented diet on diesel petroleum induced liver damage in rats was investigated. Rats were acclimatized for two weeks and divided into three groups. Oxidative stress was induced with diesel petroleum (4 ml/kg body wei...

Open access Research Article 10.9734/IJBCRR/2012/1023

Risk Assessment of Residual Pesticides of Phaseolus vulgaris L. Consumed in Port Harcourt, Rivers State, Nigeria

S. N. Kalu, C. O. Ujowundu, A. A. Emejulu, F. N. Ujowundu, V. A. Onwuliri, T. O. Ukwueze & M. A. Akpaki · Annual Research & Review in Biology · 2023

Pesticides are important and necessary in reducing the loss caused by insect infestation on grains. However, its toxicity and persistence in the environment is of health concern. Beans (Phaseolus vulgaris L.) preserved with insecticide are considered to be good for consumption if...

Open access Research Article 10.9734/arrb/2023/v38i730593

Biochemical and Oxidative Stress Responses in Clarias gariepinus Exposed to Sublethal Concentrations of Benzo[a]pyrene

U. O. Osuagwu, C. O. Ujowundu, L. A. Nwaogu & R. N. Nwaoguikpe · Asian Journal of Biochemistry, Genetics and Molecular Biology · 2023

The effect of benzo[a]pyrene (BaP) on selected plasma biochemical parameters of the tropical African catfish C. gariepinus was investigated. Apparently healthy juvenile fish (n = 90; mass = 19.7 ± 1.8 g) were exposed to sublethal concentrations of BaP over a period of 35 days aft...

Open access Research Article 10.9734/ajbgmb/2023/v13i3294

Assessment of Hematological and Serum Electrolyte of Albino Rats Administered with Graded Concentrations of Ethanol Extract of Ficus capensis

K. O. Igwe, C. O. Ujowundu, S. C. Chukwudoruo & U. K. Obasi · Asian Journal of Research in Botany · 2020

Hematological and Serum electrolyte levels of albino rats administered graded concentrations (250 mg/kg, 150 mg/kg and 100 mg/kg) of ethanol extract of Ficus capensis was assessed. Hematological parameters were analyzed with a hematological auto analyzer. Sodium, Potassium and Ch...

Open access Research Article

The Effects of Moringa oleifera Leaves Extracts on Sickle Cell Hemoglobin

R. N. Nwaoguikpe, C. O. Ujowundu, C. U. Igwe & P. N. Dike · Journal of Scientific Research and Reports · 2014

Sickle cell disease (SCD) caused by hemoglobin mutant called hemoglobin S or HbS, which originated from the replacement of a hydrophilic amino acid residue-glutamic acid by a hydrophobic moiety valine, at the sixth position of the β-chain of hemoglobin molecule. This loss of char...

Open access Research Article 10.9734/JSRR/2015/12905

Phyllantus amarus (Schum. and Thonn): An Antiplasmodial Plant

R. N. Nwaoguikpe, C. O. Ujowundu, W. Braide & J. Obi · Journal of Advances in Medicine and Medical Research · 2014

The incidence of malaria infestation has assumed epidemic status and treatment procedures have failed to yield required results due to resistance of most Plasmodial species to conventional antimalarial drugs especially in sub-Saharan Africa. Phyllantus amarus (Schum and Thonn) wa...

Open access Research Article 10.9734/BJMMR/2014/7463

Effect of Combined Ethanol Leaf Extracts of Moringa oleifera and Gongronema latifolium on Body Weight and Blood Glucose Concentration of Streptozotocin-Nicotinamide-induced Diabetic Albino Rats

S. C. Ekeh, K. M. E. Iheanacho, C. O. Ujowundu & V. C. Ofojebe · International Research Journal of Gastroenterology and Hepatology · 2019

Background: Diabetes is a major health challenge globally and it is on the increase as carbohydrate is the main food consumed by an average human. Up till now, no synthetic drug has been able to provide permanent cure for diabetes. Aim: This study investigated the effect of the c...

Open access Research Article

Biochemical Changes in Tissues of Telfaria occidentalis Leaves Following Subchronic Exposure to some Heavy Metals

L. A. Nwaogu, C. U Igwe, C. O. Ujowundu, A. A. Emejulu, C. I. Iheme & D. C. Belonwu · Current Journal of Applied Science and Technology · 2014

Aims: To investigate the biochemical changes that occurred when T. occidentalis seedlings are exposed to some heavy metals [mercury (Hg), lead (Pb) and cadmium Re(Cd)] at varying concentrations: 50, 80 and 100 μg/dm3 respectively over a period of time. Study Design: Randomized co...

Open access Research Article 10.9734/BJAST/2014/7063

Hypolipidemic Properties of Ethanol Extract of Cyperus rotundus Rhizome

G. N. Okwu, S. E. Abanobi, U. V. Nnadi, C. O. Ujowundu & A. C. Ene · International Journal of Biochemistry Research & Review · 2015

Hypolipidemic Properties of Ethanol Extract of Cyperus rotundus Rhizome This study investigated the effect of ethanol extract of Cyperus rotundus rhizome on hyperlipidemia induced with carbimazole and cholesterol in male wister rats. Acute toxicity analysis with the Cyperus rotun...

Open access Research Article 10.9734/IJBCRR/2015/17158

In vitro and in vivo Antitrypanosomal Effects of Methanol and Aqueous Extracts of Picralima nitida

A. C. Ene, N. G. Edeh, C. Bonny-Okoli, O. A. Ojiako, C. O. Ujowundu & C. U. Igwe · Journal of Pharmaceutical Research International · 2014

The methanol and aqueous extracts of the leaves, fruits, seeds, stem bark and roots of Picralima nitida were studied in vitro and in vivo for activity against Trypanosoma brucei brucei in Swiss albino mice. Phytochemicals studies were also conducted for all the plant extracts The...

Open access Research Article 10.9734/BJPR/2014/6628

The Effects of Extracts of Christmas Bush (Alchornea cordefolia) on Sickle Cell Hemoglobin

R. N. Nwaoguikpe, W. Braide, G. N. Okwu, B. O. Anyanwu & C. O. Ujowundu · Journal of Pharmaceutical Research International · 2013

The study aims at determining the antisicking effectiveness of the extracts of the leaves of a herbal medicinal plant Alchornea cordefolia. The plant is widely distributed in the South-eastern region of Nigeria. The study is designed to involve phytochemical exploration, the nutr...

Open access Research Article 10.9734/BJPR/2014/4467