Garlic, which primarily composed of diallyldisulfide and diallyltrisulfide, has been shown to inhibit cancer cell proliferation. Nuclear Factor receptor 1 (NRF2) is the master regulator of many detoxifying enzymes including glutathione. In this study, human ovarian cancer cell li...
Open access
Research Article10.9734/ajbgmb/2026/v18i3525
Gueye Mouhamadou Moustapha, Soumah Idrissa Yahya, Samba Abdourahmane, FAYE Ibrahima, Sow Harouna Ousmane, Lo Serigne Adoul Ahad, Cissé Moussa, Diedhiou Fatou, Ba Ramatoulaye, Dia Sy Fatou Kine Thorpé, Coly Nadja Fatou, Diouf Niokor, Doupa Dominique, Ndiaye Arame, Cisse Fatou, Diatta Alassane, Souleymane Thiam & Agne Diallo Fatou·Asian Journal of Biochemistry, Genetics and Molecular Biology·2026
Introduction: Hyperuricemia is a common biochemical abnormality associated with several pathologies such as chronic kidney disease, arterial hypertension, and cardiovascular diseases. The aim of our study was to determine the prevalence of hyperuricemia among hospitalized patient...
Open access
Research Article10.9734/ajbgmb/2026/v18i2524
Preeclampsia is a pregnancy disorder with numerous symptoms that affects both the mother and the child. The ameliorative potentials of Phoenix dactylifera fruit extract on selected biochemical parameters of the rat model of preeclampsia were investigated using standard analytical...
Open access
Research Article10.9734/ajbgmb/2026/v18i2523
368 records of weights from birth to 12 months for pure German brown, N’dama and their crossbreds from the crossbreeding programme carried out at the University of Ibadan, Nigeria between 1970 – 1988 was analyzed using least square means of analysis of variance and regression. B...
Open access
Research Article10.9734/ajbgmb/2026/v18i2522
Background: Hemoglobinopathies are a major public health issue in high-prevalence regions. They result from mutations affecting globin genes, causing qualitative abnormalities or quantitative defects. Phenotypic-based diagnosis often remains presumptive. Aim: This article highlig...
Open access
Research Article10.9734/ajbgmb/2026/v18i2521
Objectives: Characterization of 195 Campylobacter isolates from chicken meat and environment samples from slaughter slabs in Jos, Plateau state, Nigeria was performed to detect resistance and virulence genes and genetic relatedness of the Campylobacter species. Methods: Isolates...
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Research Article10.9734/ajbgmb/2026/v18i2520
Doxorubicin (DOXO) is one of the most dreaded antineoplastic medications often recommended for many malignancies. This study investigated the effect of aqueous extract of Commelina diffusa on doxorubicin-induced hepatic dysfunction in rats. Twenty-five Wistar rats weighing betwee...
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Research Article10.9734/ajbgmb/2026/v18i2519
Background: Hepatocellular carcinoma (HCC), the major form of liver cancer, is a significant health threat, especially in endemic areas like Nigeria, due to rising incidence and poor prognosis. Aim: This study aimed to evaluate and compare serum levels of glypican-3 (GPC3), survi...
Open access
Research Article10.9734/ajbgmb/2026/v18i1518
Hormonal interventions significantly influence pre-weaning litter characteristics in rabbits. This study looked at how different amounts of equine chorionic gonadotropin (eCG: 10-20 IU) and testosterone enanthate (TE: 4-8 IU) affected the number of kits (KN) and their weight (KW)...
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Research Article10.9734/ajbgmb/2026/v18i1517
Background: Lignocellulose, composed of cellulose, hemicellulose, and lignin, forms the main structural component of plant biomass and represents a major renewable resource for bioenergy and bio-based products. Its biodegradation is mediated by diverse microbial communities posse...
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Research Article10.9734/ajbgmb/2026/v18i1516
Osteoporosis is a significant public health concern, with over 200 million persons affected globally. In Africa, the burden of osteoporosis is rising due to increasing life expectancy and lifestyle changes. Osteoporosis in Nigeria remains underdiagnosed, yet hospital-based studie...
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Research Article10.9734/ajbgmb/2026/v18i1515
Structural biology provides the fundamental blueprint for understanding the function of macromolecules. Historically, this field has been driven by three main techniques: X-ray crystallography, which offers atomic-level snapshots of crystallizable proteins; nuclear magnetic reson...
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Research Article10.9734/ajbgmb/2026/v18i1514
Lead is used in many different products, including as paints, pigments, solder, stained glass, lead crystal glassware, ammunition, ceramic glazes, jewellery, toys. Lead exposure can result in significant and enduring harm, particularly to the liver, which is among the most impact...
Open access
Research Article10.9734/ajbgmb/2026/v18i1513
Cadmium (Cd) is an environmental toxicant that exerts oxidative stress by disrupting antioxidant defense mechanisms, causing damage to vital organs, including the liver and kidneys. This study presents a computational and experimental evaluation of S3-aminopropyl thiosulforic aci...
Open access
Research Article10.9734/ajbgmb/2025/v17i12510
Urinary tract infection (UTI) is a common bacterial infection (contagion) known to affect the different parts of the urinary tract and the occurrence is found in both males and females. The urinary system includes the kidneys, ureters, bladder and urethra. Despite the fact, that...
Open access
Research Article10.9734/ajbgmb/2025/v17i12511