Prevalence of Hyperuricemia in the Biochemistry Laboratory of Aristide Le Dantec Hospital

Abstract

Introduction: Hyperuricemia is a common biochemical abnormality associated with several pathologies such as chronic kidney disease, arterial hypertension, and cardiovascular diseases. The aim of our study was to determine the prevalence of hyperuricemia among hospitalized patients at Aristide Le Dantec Hospital. Methodology: This was a retrospective study covering the period from January 4, 2021, to January 4, 2022, focusing on serum samples from hospitalized patients sent to the biochemistry laboratory of Aristide Le Dantec University Hospital for blood uric acid measurement. Uric acid assay was performed on the ARCHITECT ci4100 analyzer (Abbott). Data were collected from the registry of results for hospitalized patients and processed using Microsoft Excel 2013. Results: Our study included 444 patients aged from 10 days to 88 years, with a mean age of 42 years and a male-to-female sex ratio of 1.27. The prevalence of hyperuricemia in our population was 61.03%, with a higher frequency among patients aged 61 to 80 years (37.63%). 53.03% of hyperuricemia cases originated from the cardiology department, followed by pediatric oncology (26.20%). The prevalence of hyperuricemia in cardiovascular diseases was 68.45%, 57.04% in cancer patients, 86.7% in renal diseases, and 75% in patients with pre-eclampsia. Conclusion: At the end of our study, we observed a high prevalence of hyperuricemia, more frequent in cardiovascular pathologies, followed by cancers and renal diseases.