In vitro Antioxidant Activity and Free Radical Scavenging Abilities of Ocimum gratissimum Leaf Extract
Moneme, E. C., Onochie, A. U., Onuegbu, M. E., Anyanwu, R. O., Ajakpofo, F. O., Oladejo, A. A.
Journal of Advances in Medical and Pharmaceutical Sciences · pp. 54–63 · Published 19 Feb 2025
10.9734/jamps/2025/v27i3758Abstract
In recent years, researchers have intensified the search for effective, non-toxic, natural edible plants with free radical scavenging activity whose effects are cushioned by antioxidant molecules. This study evaluated the in vitro antioxidant activity and free radical scavenging abilities of Ocimum gratissimum leaf extract. In vitro antioxidant (nitric oxide, Hydrogen Peroxide, Ferric Reducing property and DPPH) activities were determined using standard methods. Results showed that the leaf extract of Ocimum gratissimum considerably scavenges radicals of nitric oxide, hydrogen peroxide and DPPH in a concentration dependent manner. From the results of the study, it could be concluded that the leaf extract of Ocimum gratissimum could help to ameliorate oxidative stress and consequently improve health.
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