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Research Article Open access CC BY 4.0

Paraneoplastic Chronic Inflammatory Demyelinating Polyradiculoneuropathy Associated with Renal Cell Carcinoma – A Rare but Critical Diagnosis

M K Manu, K Ram Mohan, Mohan Amal, C Lingesh Sairam, Harikrishnan AB, SJ Aquil Faris

Asian Journal of Research and Reports in Urology · pp. 88–91 · Published 31 Oct 2024

10.9734/ajrru/2024/v7i1124

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) in the context of renal cell carcinoma (RCC) is a rare occurrence.  A 73year old male presented with 6 months history of progressive weakness, was diagnosed as CIDP. His condition deteriorated despite treatment, leading to quadriplegia. Further evaluation with imaging revealed a left sided RCC. Following radical nephrectomy, the patient experienced substantial sensory and motor function improvement. This case highlights a rare paraneoplastic link between CIDP and RCC, emphasizing the importance of considering paraneoplastic syndromes in patients with atypical or treatment-resistant neurological conditions. Early recognition and management of the underlying malignancy can significantly improve neurological outcomes.

Chronic inflammatory demyelinating polyradiculoneuropathy renal cell carcinoma paraneoplastic syndrome Quadriplegia

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