Aims: The study was conducted to evaluate the antioxidant and cytotoxic properties of crude flavonoid fraction from hybrid variety of Momordica charantia (L.) (Bitter gourd) fruit. Place and Duration of Study: The study was carried out in 2011 in the Department of Biochemistry an...
Open access
Research Article10.9734/BJPR/2014/7288
Aim: There is still a need for new, selective COX-2 inhibitors with an improved safety profile, therefore, a series of diclofenac analogues were designed and different physicochemical properties were calculated such as log P, hydrogen donor, hydrogen-acceptor, molecular weight an...
Open access
Research Article10.9734/BJPR/2014/5030
Aims: To determine the prophylactic effects of clofibrate on hyperbilirubinemia in very low birth weight twins. Study Design: A randomized double blind clinical trial Place and Duration of Study: Department of Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mas...
Open access
Research Article10.9734/BJPR/2014/5264
Objective: The present study is to evaluate antiepileptic activity of some fluoro benzothiazolo oxadiazolo quinazoline and sulfonamido quinazoline derivatives. Background of the Study: Epilepsy is a chronic disorder of the brain, characterized by the periodic and unpredictable oc...
Open access
Research Article10.9734/BJPR/2014/6876
Aims: The study was conducted to compare the presence of different phytochemicals and biological activities like cytotoxicity, anthelmintic activity, antioxidant and free radical scavenging activities between aqueous and ethanolic extract of Momordica charantia L. Fruits. Methodo...
Open access
Research Article10.9734/BJPR/2014/7364
Petroleum ether, chloroform and methanol extracts of the whole plant of Artemisia maritima Linn were studied in vitro and in vivo for antitrypanosomal activity against Trypanosoma brucei brucei in Swiss albino mice. The extracts were also screened for phytochemicals/secondary met...
Open access
Research Article10.9734/BJPR/2014/7631
Background: Medicinal herbs have long been used in the treatment of malaria in the endemic tropical and subtropical regions of the world, especially in sub-Saharan Africa where malaria has remained as a top killer disease to children under five years and expectant mothers. Among...
Open access
Research Article10.9734/BJPR/2014/6528
Background: Reports of adverse drug reactions (ADR) in the era of increasing uptake of antiretroviral drugs particularly in Sub Saharan Africa and especially in Nigeria have been on the rise. Aim: We set out to collate and characterize the pattern of adverse drug reactions in pat...
Open access
Research Article10.9734/BJPR/2014/6520
Aims: Darunavir is widely used in HIV/AIDS therapy. It is a HIV protease inhibitor that has excellent efficacy against the virus. The aim of this study is to develop and validate an analytical method fast and free of interferences for determination of darunavir ethanolate as raw...
Open access
Research Article10.9734/BJPR/2014/6326
In rural Africa, a number of alternative treatment options are explored because of poverty and unawareness. Kerosene is one such agent used for the treatment of a myriad of diseases. The aim of the study was to investigate the effects of trace amounts of kerosene on lung, heart,...
Open access
Research Article10.9734/BJPR/2014/2983