Aims: To investigate the effects of M. charantia on serum lipid profile, serum protein concentration and selected markers of cardiovascular damage in streptozotocin-induced diabetic Wistar rats. Study design: Forty healthy adult Wistar rats of both sexes were randomly assigned in...
Open access
Research Article10.9734/BJPR/2014/5320
Aims: To evaluate the In vitro cytotoxic effects of the hydro ethanolic extract (HEE) of the Delonix regia flowers against different cell lines. Methodology: The dried Delonix regia flowers are subjected to soxhlet extraction by using 70% ethanol. The dried extract was used to de...
Open access
Research Article10.9734/BJPR/2014/5746
Aims: Peripheral neuropathy (PN) is an identified risk of systemic antibacterial therapy with fluoroquinolones. The risk and its severity, including the development of Guillain-Barré syndrome (GBS) between individual agents is uncertain. This study examines the association betwee...
Open access
Research Article10.9734/BJPR/2014/6954
Aim: The study was aimed to evaluate Momordica charantia leaves extract for hepatoprotective effect against carbon tetrachloride (CCl4) induced hepatotoxicity in rats. Methodology: A total of twenty five male rats were randomly divided into five groups of five rats each. The extr...
Open access
Research Article10.9734/BJPR/2014/4885
Aims: The aim of the present work was to design and evaluate the Imatinib mesylate microspheres using natural and semi synthetic polymers for stomach specific drug delivery. Study Design: Design and Evaluation of Imatinib Mesylate loaded microspheres Place and Duration of the Stu...
Open access
Research Article10.9734/BJPR/2014/6444
This paper aimed to study the antioxidant properties of two Nigerian plants Psidium guajava (guava) Myrtaceae and Aloe vera Liliaceae plants which have a broad application in phytomedicine. The plants were assessed by quantifying their individual chemical contents and their 1:1 (...
Open access
Research Article10.9734/BJPR/2014/6989
Carl Parson, Valerie Smith, Christopher Krauss, Hirendra N. Banerjee, Christopher Reilly, Jeanette A. Krause, James M. Wachira, Dipak Giri, Angela Winstead & Santosh K. Mandal·Journal of Pharmaceutical Research International·2013
Aim: To study the efficacy of novel rhenium compounds to treat triple node negative breast cancer. Study Design: Six (6) novel rhenium pentycarbanato compounds (PC1-6) were synthesized and triple node negative breast cancer cell lines HTB-132 and Balb/c mouse kidney cell lines we...
Open access
Research Article10.9734/BJPR/2014/4697
Aim: Present study includes the development and evaluation of superporous hydrogel composites of acrylamide using starch silicone dioxide coprecipitate (SSC) as composite agent. Methodology: Gas blowing method was used for synthesis of superporous hydrogels. Different ingredients...
Open access
Research Article10.9734/BJPR/2014/6277
Aims: This study was designed to determine the effect of a high salt diet on serum bilirubin concentration and to ascertain the impact of treatment with Viscum album on same. Methodology: Twenty male albino wistar rats weighing 150 - 200g were used for this study. After seven day...
Open access
Research Article10.9734/BJPR/2014/7359
Aim: To investigate the interaction of slidenafil and green tea in normal healthy male volunteers using probe drugs (midazolam, CYP3A4 activity). Study Design: Ten healthy males were included in random crossover single dose study. Each volunteer received one tablet of sildenafi...
Open access
Research Article10.9734/BJPR/2014/6905