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International Research Journal of Gastroenterology and Hepatology

Published by SCIENCEDOMAIN international

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100

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2026 articles

100

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Articles (100)

Evaluation of the effect of Jathropha interrigima (Euphorbiaceae) on Hepatic Function of Male Albino Wistar Rats Exposed to Lead

M. J. Andy-Nwokocha, E. O. Nwachuku, E. S. Bartimaeus & C. C. Obunwo · International Research Journal of Gastroenterology and Hepatology · 2021

Aim: The aim of the study was to evaluate the effect of Jathropha interrigima on hepatic function of male Albino Wistar rats exposed to lead. Study Design: The study is an experimental study. Place and Duration of Study: Department of Animal and Environmental Biology, Rivers Stat...

Open access Research Article

Hepatoprotective Potential of Alkaloid Extracts from Vitex doniana and Ficus thonningii Leaves in Alloxan-induced Diabetic Rats

Onyinyechi C. Njoku, Augustine I. Airaodion, Olachi L. Osuagwu, Nathaniel O. Oladosu & Anthony U. Megwas · International Research Journal of Gastroenterology and Hepatology · 2021

Aim: This study sought to evaluate the hepatoprotective potential of alkaloid extracts from V. doniana and F. thonningii leaves on alloxan-induced diabetic rats. Materials and Methods: Fresh leaves of V. doniana and F. thonningii were obtained from a local market Nkwagu in Abakal...

Open access Research Article

Evaluation of Biochemical Changes in Rabbits Exposed to Sodium Cyanide

B. I. Elleh, E. S. Bartimeaus, F. U. Igwe, D. G. Tamuno-Emine & E. S. Agoro · International Research Journal of Gastroenterology and Hepatology · 2021

Aim: The aim of this study was to evaluate the biochemical changes in Rabbits due to Sodium Cyanide exposure. Study Design:  An experimental study. Place and Duration of Study: This study was carried out at Animal House, Applied and Environmental Biology Department, Rivers State...

Open access Research Article

Effect of Bambara Nut on Hepatic Biomarkers of Wistar Rats

A. I. Airaodion, P. N. Akunne, O. C. Njoku, N. O. Oladosu & A. U. Megwas · International Research Journal of Gastroenterology and Hepatology · 2021

Aim: This study sought to investigate the effect of Bambara nut on hepatic biomarkers of Wistar rats. Methodology: The Songkhla 1 variety (red seed coat) of Bambara nuts were locally sourced in Obinze area of Owerri, Imo State, Nigeria. The seeds were peeled and ground to a fine...

Open access Research Article

Treatment Strategies for Nonalcoholic Fatty Liver Disease (NAFLD) Include Lifestyle Modifications and a Major Role of Vitamin D. A Randomized Controlled Trial

Mohsin Jamil Khan & Hongyan Ge · International Research Journal of Gastroenterology and Hepatology · 2021

Aims: hypovitaminosis D may be related to the pathogenesis of the nonalcoholic fatty liver disease (NAFLD) and may contribute to NAFLD's development and progression. Our study aimed to evaluate the therapeutic effects of vitamin D supplementation in patients with NAFLD. Place and...

Open access Research Article

Hepatotoxic effect of Xylopia aethiopica Fruit in Wistar Rats

Emmanuel O. Ogbuagu, Prince C. Unekwe, Augustine I. Airaodion, Ifeoma N. Nweke & Uloaku Ogbuagu · International Research Journal of Gastroenterology and Hepatology · 2021

Background: Xylopia aethiopica fruit has been reported to possess high medicinal value. Thus, people use it without any regard for its toxicity. Aim: This study is therefore aimed at investigating its toxicity on the liver of Wistar rats. Methodology: The fruits of Xylopia aethio...

Open access Research Article

Detection and Genotypic Characterization of Hepatitis B Virus among Prospective Blood Donors at a Tertiary Healthcare Facility in Central Nigeria

Henry Chukwunonso Egbu, Haruna Isa Mohammed & Grace Rinmecit Pennap · International Research Journal of Gastroenterology and Hepatology · 2020

Aims: This study was conducted to detect and type hepatitis B virus circulating among prospective blood donors at a tertiary healthcare Facility in Central Nigeria Study Design: The study was a cross sectional study. Place and Duration of Study: Keffi, Nasarawa State, between Jan...

Open access Research Article

Patterns of Hepatitis B Virus Infection Serologic Markers among Blood Donors at a Tertiary Healthcare Facility in Central Nigeria

Henry Chukwunonso Egbu, Haruna Isa Mohammed & Grace Rinmecit Pennap · International Research Journal of Gastroenterology and Hepatology · 2020

Aims: This study was conducted to evaluate the patterns of hepatitis B virus infection serologic markers among blood donors at a tertiary healthcare Facility in Central Nigeria Study Design: The study was a cross sectional study. Place and Duration of Study: Keffi, Nasarawa State...

Open access Research Article

Hepatoprotective Effects of Hypoestes rosea in Acetaminophen-Induced Toxicity in Albino Rats

Ogregade, I. E., Igwe, F., Davies, T. G. & Bartimaeus, E. S. · International Research Journal of Gastroenterology and Hepatology · 2020

Aims: The aim of this study was to evaluate the hepatoprotective effects of Hypoestes rosea in acetaminophen-induced toxicity in albino rats. Study Design:  This study is a case-controlled interventional study. Place and Duration of Study: This study was conducted at the Experime...

Open access Research Article