Background: Acute pancreatitis (AP) is an inflammation of the pancreas that can vary from a mild, self-resolving condition to severe necrotizing pancreatitis accompanied by multi-organ failure. The disease progression is primarily driven by an excessive inflammatory response. Met...
Open access
Research Article10.9734/irjgh/2025/v8i1131
Aim: The aim of this study was to evaluate the effect of activated carbon and honey treatments on liver function in albino rats with acetaminophen-induced hepatotoxicity. Study Design: Experimental study. Place and Duration of Study: Rivers State University, between May and Septe...
Open access
Research Article10.9734/irjgh/2025/v8i1129
McHenry Stephen Ambrose, Kintasha F. Anthony, Adole Jayne, Wilberforce Rinlat, Deborah C. Dusu, Nyam D. Paul, Okorie Michael, Davwar Pantong, Adabe Bello, Duguru Mary, Yilgwan Chris, Okeke Edith, Isichie Mercy, Isichie Christian & Malu O.A·International Research Journal of Gastroenterology and Hepatology·2025
Background: Alcohol is a common cause of liver fibrosis and liver failure globally. In Nigeria, many types of alcohol are consumed, including locally brewed and industrially brewed beer and spirits. The common locally brewed alcohol here includes “Burukutu,” “Pito,” “Palm wine,”...
Open access
Research Article10.9734/irjgh/2025/v8i1128
Onyinyechi Chijioke Njoku, Linus O. Agwu, Chimdi Ezichi Esonu, Chibuike Valentine Edom, Moshood A. Haruna, Winifred N. Nsofor, Thaddeus O. Ukwueze, Nnenna C. Osuji-Kalu, Blessing A. Mba, Chinweuba G. Nwaekpe & Tasi’u M. Uba·International Research Journal of Gastroenterology and Hepatology·2025
Background: Kidney related disorders arising from several diseases has been a challenge in recent times. The aim of this study was to evaluate the effect of A. muricata ethanol leaf extract on renal function parameters of NMU-induced prostate cancer in albino rats. Materials and...
Open access
Research Article10.9734/irjgh/2025/v8i1127
Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease that often requires surgical intervention, such as colectomy, in severe cases. C-reactive protein (CRP) is an established marker of inflammation, and its role as a predictor of colectomy in patients with...
Open access
Research Article10.9734/irjgh/2025/v8i1125
Aim: To estimate the activities of aspartate amino transaminase (AST), alanine amino transaminase (ALT), alkaline phosphatase (ALP), Gamma glutamyl transpeptidase (GGT) Lactate dehydrogenase (LDH) as well as concentrations of alpha fetoprotein, C reactive Protein and viral load i...
Open access
Research Article10.9734/irjgh/2025/v8i1126
Background: Rotavirus remains a leading etiological agent of acute gastroenteritis and severe diarrhoea in young children globally. Despite the availability of effective vaccines, the burden of disease remains substantial in low-resource settings due to poor vaccine uptake, poor...
Open access
Research Article10.9734/irjgh/2025/v8i1124
Aim: To determine the prevalence, molecular characteristics, and antibiotic susceptibility pattern of Enteropathogenic Escherichia coli (EPEC) strains isolated from children under five years of age presenting with acute diarrhoea in Abuja, Nigeria, and to evaluate the utility of...
Open access
Research Article10.9734/irjgh/2025/v8i1123
Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. Although curative treatments such as surgical resection and liver transplantation offer potential for long-term survival, recurrence remains a significant challenge. Immune checkp...
Open access
Research Article10.9734/irjgh/2025/v8i1122
Aim: This study investigated the toxicological effect and the biochemical changes in the liver after the administration of Azadirachta indica (Neem) extract and a mixture of edible camphor in albino Wistar rats. Study Design: Experimental study. Place and Duration of Study: Depar...
Open access
Research Article10.9734/irjgh/2025/v8i1121