Background: splanchnic vasodilatation is a major contributor to development of ascites n cirrhotic patients and associated with poor sodium excretion. So Midodrine which is, alpha 1 agonist, may improve circulatory abnormality in cirrhotic patients via its vaso-constrictive acti...
Background: Tramadol is an opioid-like analgesic or pain-relieving agent, used parenterally and orally for the treating moderate or severe painful sensation. Because the drug is inexpensive and is not classified as control drug by the government, the authors attempt to establish...
Introduction: Upper GI Endoscopy is one among the most commonest tool used by gastroenterologists to define the etiology of dyspepsia. Is this the final decree for all dyspeptic patients or we have to change our decisions as per the resouce available? This study tried to look ove...
Owing to its extensive blood supply and significant role in metabolism, the liver is particularly susceptible to xenobiotics. Thus, it is exposed to high doses of the toxicant or toxic metabolites. The kidney is highly susceptible to toxicants because a high volume of blood flows...
Background: The pancreas can be imaged using ultrasound to provide details on its size, echotexture, ductal anatomy, and surrounding tissues. Diagnostic and interventional procedures can be easily completed quickly and for a low cost. Objectives: To determine the normal pancreati...
Peptic ulcer disease is a chronic condition of the gastrointestinal tract that results from an imbalance between protective and aggressive factors of the gastric mucosa. Many synthetic drugs are used for the treatment of this disease, but they are costly and exhibit limited effic...
Foodborne gastroenteritis, security and safety is a global concern in today’s world, in that regard it is a major concern to public health policies however foods vendor are patronized on daily bases in urban and suburban cities in Nigeria. This study is aimed at investigating the...
Salmonella enterica, serotype Typhi, remains the predominant Salmonella species causing enteric fever. This disease threatens public health as it is associated with personal hygiene techniques and practices. This study investigates Salmonella typhi using conventional bacteriologi...
The most prevalent condition affecting the stomach and duodenum is peptic ulcer disease (PUD), which is linked to Helicobacter pylori (H. pylori) infection. Esophageal, duodenal, and stomach ulcers are all parts of peptic ulcer disease (PUD). Epigastric discomfort is the PUD symp...
The CYP450 enzyme family is most responsible for the biotransformation of endobiotic and exobiotic. Eventually, this family will consist of the most abundant drug-metabolizing enzymes. Though the liver is the major metabolizing organ for drugs and xenobiotics, orally administered...