Early diagnosis of disease is highly recommended for the treatment purposes by the clinicians. Thalassemia is a genetic disorder which can be inherited from the parents. Thalassemia is classified into two groups alpha thalassemia and beta thalassemia depending upon the severity o...
Open access
Research Article10.9734/IBRR/2015/16178
Background: Sickle cell disease (SCD) remains a major health burden in Sub-Saharan Africa and the management requires regular monitoring of the patients. The monitoring includes routine assessment of haematological parameters and any deviation can best be appreciated when steady...
Open access
Research Article10.9734/IBRR/2015/18339
Susana Perez, Irma Bragós, Mariana Raviola, Arianna Pratti, Germán Detarsio, Sandra Zirone, Maria Eda Voss, Luciano Verón, Irma Acosta & Mara Ojeda·International Blood Research & Reviews·2015
Hemoglobin (Hb) Sabine is an unstable Hb variant that causes hemolytic anemia in heterozygous state, with inclusion bodies in the red blood cells (RBC). This hemoglobin is the result of a point mutation at codon 91(CTG)®(CCG) of the beta-globin gene. We report, for the first time...
Open access
Research Article10.9734/IBRR/2015/18559
Mohamed Kaled A. Shambesh, Ezzadin Areaf Franka, Faisal Fathalla Ismail, Nagi Meftah Gebril, Kamel Ahmed Azabi & Fatma Amar·International Blood Research & Reviews·2015
Background: Post transfusion hepatitis B (PTHB) continues to be an important public health concern with regard to blood transfusion in Libya and in Africa. This concern is related to the screening test which is still used but it is not enough to detect infective cases during wind...
Open access
Research Article10.9734/IBRR/2015/18364
Background: Acquired pure red cell aplasia (PRCA) is a rare disease characterized by anemia, severe reticulocytopenia and absent to low bone marrow erythroid precursor cells. There are well-described associations of this disorder with thymomas, lymphoproliferative disorders, auto...
Open access
Research Article10.9734/IBRR/2015/17728
Background: Sickle cell anaemia is a chronic anaemia that is characterized by episodes of severe bone pain from blood vessels occlusion by sickled red blood cells when deoxygenated, and eventual end organ affectation and multi-organ failure. The aim of this study was to compare t...
Open access
Research Article10.9734/IBRR/2015/17811
Introduction: Blood transfusion remains a vital component of modern medicine, as yet artificial blood or blood substitute is still widely promising. In well-organized health care systems, with standard transfusion services/facilities and safe practices, the risk associated with i...
Open access
Research Article10.9734/IBRR/2015/17874
Feryal Karaca, Cigdem Usul Afsar, Fatma Sert, SebnemIzmir Guner, Vehbi Ercolak, Erkut Erkurt & Candas Tunali·International Blood Research & Reviews·2015
Introduction: Non-hepatosplenic Extramedullary Hematopoiesis (NHEMH) is seen as a compensation mechanism in the patients with hematologic dysfunction. Thalassemia is an autosomal recessive hematologic disorder. The tissue involvement is seen very rarely in thalasemia major. Case:...
Open access
Research Article10.9734/IBRR/2015/17235
Background: Incorrect blood sample volume-anticoagulant ratio has been the cause of both haematological and immunological errors especially when K3 EDTA-containing blood collection tubes were used. Lower whole blood sample volumes collected into 4.0 millilitres spray-dried K2 EDT...
Open access
Research Article10.9734/IBRR/2015/16338
Background: ABO and rhesus blood group study is very relevant to the blood transfusion services policy maker and clinicians. ABO and rhesus blood group are the most prevalent blood groups among so many other blood groups discovered. Aims: The aim of this study was to find out the...
Open access
Research Article10.9734/IBRR/2015/16278