Background: Myocardial infarction is one of the leading causes of death worldwide. Altered amino acids metabolism is linked to cardiovascular disorders. A cross-sectional case control study was set to profile amino acids explore their potential as diagnostic and prognostic tool....
Open access
Research Article10.9734/ijbcrr/2022/v31i330310
Objective: To investigate the association between plasma free amino acids (PFAAs) profile changes, vitamin D concentration and hypertension and evaluate the clinical utility of this association for nascent hypertension before the development of complications. Methods: 70 subjects...
Open access
Research Article10.9734/ijbcrr/2020/v29i930232
Aims: Certain liver diseases can cause decreased synthesis of liver proteins or enzymes, including biotinidase, thereby reducing biotinidase activity in serum. The present study aimed to assess plasma biotinidase level in pediatric patients with compensated and decompensated chro...
Open access
Research Article10.9734/IJBCRR/2017/32764
Aims: Inborn errors of metabolism (IEM) constitute a group of inherited disorders that cause significant morbidity and mortality. This diverse group of diseases present with different clinical manifestations that make the diagnosis a real challenge. The current work aimed to inve...
Open access
Research Article10.9734/IJBCRR/2016/31021
Aims: Gaucher disease "GD" is one of the most common glycolipid storage disorders. Several circulating molecules thought to be secreted by Gaucher cells have been studied as biological markers of disease. We investigate and compare the validity of using plasma chitotriosidase "Ch...
Open access
Research Article10.9734/IJBCRR/2017/32782
Aims: We evaluate the effect of enzyme replacement therapy "ERT" on the plasma levels of some biochemical markers of the disease burden, in pediatric patients with Gaucher's disease "GD", in the form of plasma chitotriosidase "ChT", total acid phosphatase activity, ferritin and g...
Open access
Research Article10.9734/IJBCRR/2016/30768