Aim: The study was designed to comparatively assess the degree of fibrinolytic response amongst malaria-positive pregnant women, and non-malaria positive subjects in Rivers State, Nigeria. Methods: The study area covered University of Port Harcourt Teaching Hospital, Port Harco...
Open access
Research Article10.9734/ibrr/2020/v11i230128
Background: Blood storage is associated with progressive biochemical and cellular changes that may alter the concentrations of soluble adhesion molecules. Vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), and P-selectin (SELP) are important m...
Open access
Research Article10.9734/jammr/2026/v38i106208
Background: Storage of whole blood is accompanied by biochemical and cellular changes that may alter soluble adhesion molecules. This study evaluated serum concentrations of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), and P-selectin dur...
Open access
Research Article10.9734/ibrr/2026/v17i4400
Sickle cell disease is a systemic vasculopathy in which intravascular haemolysis, endothelial activation, leukocyte and platelet recruitment, and coagulation activation operate as a single self-reinforcing process now commonly described as thromboinflammation. Most of the mechani...
Open access
Research Article10.9734/ibrr/2026/v17i4399
Introduction: Haematologic and haemostatic abnormalities are common complications of human immunodeficiency virus (HIV) infection. These abnormalities intensify in the course of the disease. In both antiretroviral-treated and naïve individuals, varied types of haematologic and ha...
Open access
Research Article10.9734/ahrj/2025/v8i3203
This case-control study investigated the effects of the AstraZeneca COVID-19 vaccine on coagulation parameters in a cohort of 102 individuals, revealing a significant increase in activated partial thromboplastin time (aPTT) among vaccinated individuals (34.233±0.653 seconds vs 28...
Open access
Research Article10.9734/ijr2h/2025/v8i1171
The COVID-19 pandemic has underscored the imperative of effective vaccination strategies, and the AstraZeneca COVID-19 vaccine has been extensively deployed globally, including in Nigeria. However, the haematological effects of this vaccine in the Nigerian population remain poorl...
Open access
Research Article10.9734/ijr2h/2025/v8i1170
Cervical cancer remains a significant global health concern, with a high incidence and mortality rate among women. This study was aimed at evaluating the alterations in haematological parameters of cervical cancer subjects in Port Harcourt. This study is a case control study. A t...
Malaria is a highly inflammatory disease characterised by periodic fever, headache, and nausea, which correspond to the rupture of infected erythrocytes and the release of merozoites that replicate within the host to produce newly formed daughter parasites. The aim of this study...
Open access
Research Article10.9734/ijr2h/2026/v9i2238
Introduction: Chronic inflammation plays a key role in the development and progression of diabetic complications. Haematological inflammatory indices have emerged as reliable markers of systemic inflammation in diabetes. Aim/Objectives: This study aimed to evaluate the neutrophil...
Open access
Research Article10.9734/ibrr/2025/v16i2354
Coronavirus disease 2019 (COVID-19) is a novel and highly contagious viral infection caused by Sars-cov-2 and has been associated with a hyper-inflammatory immune response. This study aimed to evaluate changes in some inflammatory cytokines as clinical biomarkers to aid in the ef...
Background: In developed countries, heart disease and stroke are the major causes of death. One of the main risk factors of cardiovascular disease is dyslipidemia, and this could be due to increased lipoproteins and/or decreased plasma clearance. Pregnancy is marked with changes...
Open access
Research Article10.9734/jammr/2022/v34i1431388
Cement dust exposures has been reported to result in significant occupational health problems and long term complications and symptoms. This study was aimed at assessing the impact of work hours on haematological parameters of cement workers. 100 cement loaders were selected in a...
Open access
Research Article10.9734/ajbgmb/2022/v12i130286