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S. P. N. N. Senadeera

Publications (12)

The Role of Neutrophils, Lymphocytes and Monocytes in Ischemic Heart Disease: Friend or Foe?

S. P. N. N. Senadeera, D. S. H. S. Peiris, D. T. K. Fernando, D. U. Kottahachchi & C. B. Ranaweera · Cardiology and Angiology: An International Journal · 2024

Ischemic heart disease (IHD) remains a leading cause of morbidity and mortality globally. In recent years research has increasingly focused on the interplay between the white blood cells and the development and progression of IHD. Neutrophils, lymphocytes, and Monocytes play an i...

Open access Research Article 10.9734/ca/2024/v13i2407

Review on Artocarpus nobilis Thw. (Moraceae): An Endemic Plant of Sri Lanka

S. P. N. N. Senadeera, C. B. Ranaweera & A. R. N. Silva · Asian Plant Research Journal · 2022

The genus Artocarpus consists of about 50 species of large evergreen trees with various medicinal and economical uses. Artocarpus nobilis (Family: Moraceae) is commonly referred to as Ceylon breadfruit and it is endemic to Sri Lanka. Synonyms of A. nobilis are Artocarpus imperial...

Open access Research Article 10.9734/aprj/2022/v10i1183

In vitro Anti-inflammatory Activity of Endemic Artocarpus nobilis Thw Found in Sri Lanka

S. P. N. N. Senadeera, K. S. K. Fernando, W. L. L. N. Wickramasekara, M. Y. S. Fernando, C. B. Ranaweera, Weranga Rajapaksha & A. R. N. Silva · Asian Plant Research Journal · 2021

Aims: To investigate in vitro anti-inflammatory activity of aqueous, methanol, dichloromethane, and hexane extracts of Artocarpus nobilis Thw. leaves and stem bark using heat-induced protein denaturation test (egg albumin denaturation). Methodology: About 500 g of each matured, f...

Open access Research Article 10.9734/aprj/2021/v8i430192

Antibacterial Activity of Endemic Artocarpus nobilis Thw Found in Sri Lanka

S. P. N. N. Senadeera, K. S. K. Fernando, W. L. L. N. Wickramasekara, M. Y. S. Fernando, C. B. Ranaweera, Weranga Rajapaksha & A. R. N. Silva · South Asian Journal of Research in Microbiology · 2021

Aims: To evaluate antibacterial activity of aqueous, methanol, dichloromethane, and hexane extracts of Artocarpus nobilis Thw. leaves and stem bark against Escherichia coli and Staphylococcus aureus using agar well diffusion method. Methodology: Matured fully expanded leaves and...

Open access Research Article 10.9734/sajrm/2021/v11i330254

Phytochemical Testing Methodologies and Principles for Preliminary Screening/ Qualitative Testing

Luvedika Maheshwaran, Ladhurshika Nadarajah, S. P. N. N. Senadeera, C. B. Ranaweera, A. K. Chandana & R. N. Pathirana · Asian Plant Research Journal · 2024

Plants are basically biosynthetic factories that contain various pathways that produce phytochemicals with the help of different parts of the cell while specialized cells or tissues hoard and use them as needed. Human population has used this to their advantage for centuries. Aim...

Open access Research Article 10.9734/aprj/2024/v12i5267

Role Played by Biochemical and Hematological Parameters in the Prediction of Cardiovascular Risk

W. K. T. Nuwanthika, D. I. K. Welivitigoda, S. P. N. N. Senadeera, D. U. Kottahachchi, C. B. Ranaweera & N. Wijesinghe · Asian Journal of Research in Biochemistry · 2024

Introduction: The term “cardiovascular diseases” (CVDs) refers to any disease affecting the heart or blood vessels. CVDs are the most common cause of death worldwide and the most responsible reason for 10% of deaths in the early 20th century. These CVDs can emerge as myocardial i...

Open access Research Article 10.9734/ajrb/2024/v14i2278

Therapeutic Potential of Carica papaya Linn.: A Comprehensive Review of Its Pharmacological Properties and Health Benefits, with Emphasis on Dengue Fever Healing

D. T. K. Fernando, D. S. H. S. Peiris, S. P. N. N. Senadeera & C. B. Ranaweera · Asian Plant Research Journal · 2024

For thousands of years, people have used various plant products, foods, spices, and herbs to treat and prevent illnesses. Sri Lankans have been using traditional and folk medicine to satisfy their basic health needs from the earliest days. Carica papaya Linn. (Caricaceae) is a co...

Open access Research Article 10.9734/aprj/2024/v12i1242

A Comprehensive Review of Salacia reticulata: Botanical, Ethnomedicinal, Phytochemical, and Pharmacological Insights

D. S. H. S. Peiris, D. T. K. Fernando, S. P. N. N. Senadeera & C. B. Ranaweera · Asian Plant Research Journal · 2023

Salacia reticulata (HIPPOCRATEACEAE) is a large ligneous climber or scandent shrub held by Sri Lanka, the Andaman Islands, and south India. It is known as Kothala himbutu/Himbutu wel in Sinhalese and is well-known among natives for its extensive use in diabetes treatment, a chron...

Open access Research Article 10.9734/aprj/2023/v11i6228

Evaluation of In vitro Anti-Inflammatory and Antibacterial Properties of Tuberous Roots of Mirabilis jalapa L. Found in Sri Lanka

D. T. K. Fernando, D. S. H. S. Peiris, S. P. N. N. Senadeera, A. K. Chandana & C. B. Ranaweera · Asian Journal of Research in Botany · 2023

Aims: This study aims to evaluate the in vitro anti-inflammatory and antibacterial potential of aqueous and various organic solvent (methanol, dichloromethane, and hexane) extracts of Mirabilis jalapa L. tuberous roots. Methods: Heat-induced egg albumin denaturation inhibition as...

Open access Research Article

Phytochemical Screening for Medicinal Plants: Guide for Extraction Methods

D. S. H. S. Peiris, D. T. K. Fernando, S. P. N. N. Senadeera & C. B. Ranaweera · Asian Plant Research Journal · 2023

Sri Lankans have relied on traditional medicine to meet their primary health needs since the beginning of time. This island is blessed with an enormous number of medicinal plants, which play a very important role in traditional medicine. However, the lengthy documented history of...

Open access Research Article 10.9734/aprj/2023/v11i4216

Rich Diversity & Potential Medicinal Value of Endemic Sri Lankan Plant: Jeffreycia zeylanica

Thumuli Udara Samaraweera, Thummini Umasha Samaraweera, S. P. N. N. Senadeera & C. B. Ranaweera · Asian Plant Research Journal · 2022

The genus Jeffreycia consists of about 109 species to have medicinal properties. Jeffreycia zeylanica (Family: Asteraceae) is commonly referred to as “Heen-botiya, Papula or Pupula in Sinhala and Kappilay or Kuppilay in Tamil”. It is an endemic herbaceous plant in Sri Lanka. Syno...

Open access Research Article 10.9734/aprj/2022/v10i4197

Evaluation of the pH-Dependent Anti-Inflammatory Potential of Mirabilis jalapa Linn. Root Extract Using Protein Denaturation and Membrane Stabilisation Assays

T. G. S. Geethika, H. M. P. K. Bandara, R. M. A. H. B. Ranathunga, S. P. N. N. Senadeera, R. S. J. Udari, D. U. Kottahachchi, C. B. Ranaweera & N. R. M. Nelumdeniya · Asian Plant Research Journal · 2026

Background: Inflammation is a biological response characterised by redness, oedema, fever, pain, and loss of function. Medicinal plants have long served as a valuable source of anti-inflammatory compounds, and Mirabilis jalapa Linn. (Four O’clock plant) is traditionally used in f...

Open access Research Article 10.9734/aprj/2026/v14i5394