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Mamadou WELE

Publications (13)

Antiplasmodial Potential and Phytochemical Screening of Ten Plants Used as Antimalarial in Mali

Mamadou WELE, Laura Kirkman, Nouhoum Diarra, Yaya Goita, Moriba Doumbia, Kassim Traore & Drissa Diallo · European Journal of Medicinal Plants · 2017

Aim: This study was designed to determine in vitro antiplasmodial activities of extracts from ten Malian medicinal plants against P. falciparum strains. Place and Duration of Study: Collection of plant materials and basic phytochemical screening were done in Bamako, Mali and anti...

Open access Research Article 10.9734/EJMP/2017/34523

SNPs on ABC Transporters and in vivo Malaria Parasite Non Clearance after Chloroquine Treatment in Malian Children

Mamadou WELE, Abdoul Habib Beavogui, Mamadou Tekete, Antoine Dara, Seydou Z Maiga & Abdoulaye DJIMDE · Journal of Advances in Medicine and Medical Research · 2013

Background: pfcrt K76T mutation was demonstrated to play a central role in the P. falciparum resistance to chloroquine. Aim: To find any association between mutant alleles of pfcrt K76T, pfmdr1 N86Y, pfG30 and pfG47 and the in vivo parasite non clearance after chloroquine treatme...

Open access Research Article 10.9734/BJMMR/2013/2434

Presence of Escherichia coli, Salmonella Species, and Staphylococcus aureus in Street Foods in Bamako, Mali

Demba DEMBELE, Mamadou WELE, Haziz Sina, Sory Ibrahim DIAWARA, Dansiné DIARRA, Ousmane Diarra & Lamine Baba-Moussa · Microbiology Research Journal International · 2025

Introduction: Foodborne illnesses are becoming an increasingly significant public health challenge in both developed and developing countries. The most common causes of foodborne illnesses worldwide are bacteria pathogens, among them Escherichia coli, Salmonella spp, Staphylococc...

Open access Research Article 10.9734/mrji/2025/v35i121688

Building Sustainable Bioinformatics Training Programs in Africa: Insights from ACE-Mali

Cheickna Cissé, Mamadou WELE, Jeffrey G. SHAFFER, Jian Li, Christopher WHALEN, Maria Y. GIOVANNI, Mariam QUINONES, Alia BENKALAH, Doulaye Dembélé, Darrell HURT, Abdoulaye DJIMDE, Karlynn NOBLE, Cheick O. TANGARA, Mahamadoun H. TOURE, Boubacar YALCOUYE, Oudou DIABATE, Abdoulaye DIAWARA, Fatoumata G. FOFANA, Mamadou Sangare, Kangaye DIALLO, Fatumo SEGUN, Mike TARTAKOVSKY, Mahamadou DIAKITE & Seydou O. DOUMBIA · Current Journal of Applied Science and Technology · 2025

Introduction: The African Center of Excellence in Bioinformatics and Data-Intensive Science (ACE), a public-private partnership, facilitated by the National Institute of Allergy and Infectious Diseases (NIAID), the National Institutes of Health (NIH), in collaboration with Africa...

Open access Research Article 10.9734/cjast/2025/v44i84599

Advances in Malaria Vaccine Development Targeting Plasmodium falciparum Surface Proteins

Fatoumata Gnine FOFANA, Mamadou WELE, Oudou DIABATE, Cheickna Cissé, Abdoulaye DIAWARA, Mahamadoun Haram TOURE, Mahamadou DIAKITE, Seydou O. DOUMBIA & Abdoulaye DJIMDE · Annual Research & Review in Biology · 2025

Malaria remains a significant public health concern, especially in endemic regions where increasing drug resistance poses challenges to effective treatment. Vaccine development has emerged as a crucial strategy for malaria control, targeting different stages of the parasite’s lif...

Open access Research Article 10.9734/arrb/2025/v40i92300

Phytochemistry and Biological Activities of Leaves and Pulp Extracts from Ziziphus mauritiana (Lam.) Collected in Mali

Singou Keita, Mamadou WELE, Cheickna Ciss, Issiaka Togola, Nouhoum Diarra & Lamine Baba-Moussa · Journal of Advances in Biology & Biotechnology · 2020

Introduction: The objectives of this work consisted of a phytochemical study of the leaves and pulp of Ziziphus mauritiana Lam collected from the flooded and dried sites of Niono and Sévaré in Mali and to evaluate the biological activities of the extracts, i.e. the antiradical ac...

Open access Research Article 10.9734/jabb/2020/v23i130133

Antibacterial and Antiplasmodial Activities of Tannins Extracted from Zizyphus mauritiana in Mali

Singou Keita, Mamadou WELE, Cheickna Cissé, Nouhoum Diarra, Laura Kirkman & Lamine Baba-Moussa · International Journal of Biochemistry Research & Review · 2018

Aim: This study was designed to evaluate tannins extracted from Ziziphus mauritiana as source of potential antimalarial and antimicrobial agents in Mali. Place and Duration of Study: Collection of plant materials, tannins extraction, antibacterial activity evaluation were done at...

Open access Research Article 10.9734/IJBCRR/2018/45335

Microbial Contamination Potential and Antibiotic Resistance Profile of Staphylococcus aureus and Escherichia coli Isolated from Ipomoea batatas Leaf

Paul Yao Attien, Clément Kouassi Kouassi, Mamadou WELE, Haziz Sina & Lamine Baba- Moussa · International Journal of Pathogen Research · 2020

Traditional leafy vegetables are recommended because there are important sources of nutrients and they protect against certain non-communicable diseases. This study aimed at assessing the microbiological quality of Ipomoea batatas leaves and evaluating the susceptibility to antib...

Open access Research Article 10.9734/ijpr/2020/v5i430148

PfDHFR Resistance Mutations in Mali: Impact on Protein Structure and Identification of Novel Natural Inhibitors

Cheickna Cissé, Oudou DIABATE, Fatoumata Gnine FOFANA, Ibrahim KEITA, Seydou Doumbia, Ousmane KOITA & Mamadou WELE · Biotechnology Journal International · 2025

Malaria drug resistance remains one of the greatest challenges to the malaria control program in Mali. Mutation in the Plasmodium falciparum Dihydrofolate Reductase (PfDHFR), a key enzyme in the folate biosynthesis pathway and primary target of antifolate drugs, are knows to indu...

Open access Research Article 10.9734/bji/2025/v29i6813

Metagenomic Identification of Bacillus thuringiensis within the Bacterial Microflora of Soils under Rice and Wheat Cultivation in Diré, Mali

Sitapha COULIBALY, Kangaye Amadou Diallo, Sognan Dao, Aïssé BAH, Adounigna Kassogué, Abdou BALLO, Modibo Maïga, Oumar Boncano TRAORE, Mamadou WELE & Amadou Hamadoun Babana · Asian Research Journal of Agriculture · 2025

Aims: This study aimed to identify and characterize the presence of Bacillus thuringiensis (Bt) within the soil bacterial microflora under rice and wheat cultivation in Diré, northern Mali, where pest pressure is notably low. Study Design: A cross-sectional metagenomic survey of...

Open access Research Article 10.9734/arja/2025/v18i3759

Prioritisation of Promising Therapeutic Targets in Plasmodium falciparum Using in Silico Multi Criteria Scoring

Mamadou Sangare, Cheickna Cissé, Bakary N'tji Diallo, Alia Benkahla, Jian Li, Jeffrey G Shaffer, Seydou Doumbia, Annie Degroot & Mamadou WELE · Biotechnology Journal International · 2025

Background: Malaria remains one of the deadliest infectious diseases globally, causing over 597,000 deaths each year, with Plasmodium falciparum (Pf) responsible for the most severe cases. Sub-Saharan Africa remains the most affected region of the world, the region hosting more t...

Open access Research Article 10.9734/bji/2025/v29i5790

Microbiome Responses to RYMV Infection: Insights from Rice Cultivation in Mali

Kangaye Amadou Diallo, Cheickna Cissé, Amadou Hamadoun Babana, Thomas Shier, Trevor Gould, Sognan Dao, Adounigna Kassogué, Doulaye Dembélé & Mamadou WELE · Advances in Research · 2024

Background: The Rice Yellow Mottle Virus (RYMV) is one of the most significant viral pathogens affecting rice production in Sub-Saharan Africa, leading to yield losses as high as 100% in severely affected areas. In Mali, particularly in the Office du Niger region, RYMV poses a co...

Open access Research Article 10.9734/air/2024/v25i61213

Assessment of the Diversity of Endophytic, Rhizospheric and Soil Bacteria Using a Targeted Metagenomic Approach in Mali

Adounigna Kassogué, Soufiana Traore, Sognan Dao, Antoine Dara, Sekou Sissoko, Cheickna Cissé, Kangaye Amadou Diallo, Rokiatou Fané, Atia Traoré, Mamadou WELE & Amadou Hamadoun Babana · Annual Research & Review in Biology · 2024

Aims: This study investigates the diversity of endophytic, rhizospheric, and soil bacterial species in agricultural ecosystems in Mali using a targeted metagenomic approach based on 16S rRNA sequencing. The primary aim is to characterize microbial communities and understand their...

Open access Research Article 10.9734/arrb/2024/v39i122179