Background: Port Harcourt’s creek systems support fisheries while receiving domestic sewage, industrial effluent, and petroleum-related waste. Lead, chromium, and cadmium are persistent contaminants that can accumulate in fish tissues and create ecological and dietary concerns. T...
Open access
Research Article10.9734/ajmah/2026/v24i71399
Background: The Niger Delta region of Nigeria hosts one of the largest crude oil reserves in Africa. Decades of oil exploration and production have released a wide range of toxic heavy metals into the environment. While lead (Pb), cadmium (Cd), and nickel (Ni) have attracted cons...
Open access
Research Article10.9734/jamps/2026/v28i7872
Background: The study is a systematic review focusing on the tartrazine and carmoisine toxicity on renal, hepatic, pancreatic, glucose metabolism, and haematological indices in albino rats. Method: We systematically reviewed studies published using keywords and short medical term...
Open access
Research Article10.9734/ajrb/2026/v16i2482
Introduction: The study is a systematic review focusing on the contamination of hands and how it results in the spread of infectious diseases, as well as health risks and challenges associated with it. Method: We systematically reviewed studies published using keywords and short...
Open access
Research Article10.9734/ajrid/2026/v17i2532
Colours are an important component of food and food products stimulating the desired psychological satisfaction, particularly in children. The study was designed to evaluate the severity, signs, and symptoms of tartrazine and carmoisine toxicity in albino rats. A total of 160 rat...
Open access
Research Article10.9734/ajrb/2025/v15i3385
A study of azorubine toxicity on reproductive hormones and gonads of albino rats was carried out. A total of 80 albino rats weighing approximately 0.15kg were used, of which a total of 40 rats were used for the intraperitoneal study and another 40 were used for the oral study. Th...
Open access
Research Article10.9734/ajrre/2025/v8i1107
Background: Co-morbidity of infections and non-infectious diseases is increasing in developing societies with little effort in identifying these trends. The study aimed to estimate the prevalence of Helicobacter pylori, Mycobacterium tuberculosis, malaria infections, and high ser...
Open access
Research Article10.9734/ijtdh/2024/v45i21515
Ibioku Elekima, Thankgod Prince Ohaka, Ngozi Brisibe, Adline Ben-Chioma, Ibitoroko George-Opuda, Orbenyie Mary Festus, Ani Precious Onyinyechi & Waribo Helen Anthony·International Journal of Biochemistry Research & Review·2022
Aim: To study the effect of exposure to crude oil on the liver, ovary, and some oxidative stress parameters in albino rats. Study Design: A total of 50 female albino rats were used in the experiment. The rats were grouped into three: The control group which consisted of 10 rats,...
Open access
Research Article10.9734/ijbcrr/2022/v31i10783
To assess and compare the levels of arsenic, cadmium, mercury and lead, in common seafoods (mudskippers, periwinkle and Shrimp) consumed in Rivers state obtained from different creeks of Rivers State Nigeria. Study Design: Commonly consumed seafoods in Rivers State: Periopthalmus...
Open access
Research Article10.9734/jamps/2020/v22i1030198
Aim: To assess the effect of tartrazine at ADI doses on ovarian integrity (the weight and histology of the ovary), reproductive fertility hormones (luteinizing hormones (LH), follicle stimulating hormone (FSH) and prolactin (PRL)) and oxidative stress markers (glutathione peroxid...
Open access
Research Article10.9734/ajbgmb/2020/v5i430136
Aim: To study the effect of chronic exposure of tartarzine at ADI doses on some biochemical parameters of male albino rats. Study Design: The design involved chronic study. In the study, the experiment was divided into phase 1, 2, and 3 which lasted for 30, 60 and 90 days respect...
Open access
Research Article10.9734/ajrb/2019/v5i130083
Aim: To evaluate the haematological alterations induced by tartrazine after acute and chronic administration in albino rats. Study Design: The design involved acute and chronic study. The acute study investigated the intraperitoneal and oral route of administration while the chro...
Aim: To determine the acute and chronic effect of tartrazine on reproductive steroid hormones of albino rats. Study Design: The design involved acute and chronic study. The acute study investigated intraperitoneal and oral route of administration while the chronic study used oral...
Open access
Research Article10.9734/ajrre/2019/v2i12
Aim: The aim of the study was to correlate anthropometric data with atherogenic indices of students in Rivers State University, Port Harcourt as a means of assessing their cardiovascular health. Study Design: A pilot study was carried out in Rivers State University, Port Harcourt...
Open access
Research Article10.9734/ajrimps/2019/v6i130092
Background: Fever plays an important role in causing disturbances in fluid and electrolyte balance. Hyponatraemia has been thought to enhance susceptibility to seizures associated with febrile illnesses in childhood. Severe hyponatraemia and a non-significant increase in potassiu...
Open access
Research Article10.9734/ajmah/2026/v24i101437
Background: Febrile seizures are common in early childhood and may involve measurable neuroinflammatory responses. Aims: This study evaluated whether palm kernel oil (PKO) modifies selected pro-inflammatory and damage-associated markers in Wistar rat pups exposed to lipopolysacch...
Open access
Research Article10.9734/jammr/2026/v38i76167
Guava leaves (Psidium guajava) have been used traditionally for years to treat common ailments such as Diabetes, diarrhoea, and hypertension. This study was designed to determine the anti-arthritic, anti-inflammatory, and antioxidant effect of the ethanolic extract of guava leaf...
Open access
Research Article10.9734/jocamr/2023/v24i3503
Aim: To investigate the alteration of some sperm proteins, anti-oxidants, and prostate-specific antigen in the seminal plasma of bacteriospermic infertile males. Study Design: The study is a case-control design to investigate the semen parameters and some sperm proteins in infer...
Open access
Research Article10.9734/jamps/2022/v24i430294
Aim: The study aimed to investigate the relationship between some heavy metals and total antioxidant capacities, glutathione levels, fructose, and testosterone in seminal plasma of infertile azoospermic and oligospermic males in Akwa Ibom State of Nigeria. Study Design: A cross-...
Open access
Research Article10.9734/jamps/2021/v23i530235
Aim: To compare the effect of oral and injectable hormonal contraceptives on lipid parameters, calcium, phosphate and some atherogenic indices among women in Rivers Sate University community, Port Harcourt, Nigeria. Study Design: One hundred and fifty (150) women between the age...
Moringa plant is an ancient medicinal plant that is widely researched using its leaves, but limited work is done on the stem. Empirical studies using albino rats reveal how good Moringa leaves are in combating hyperlipidemia and hyperglycemia. The study was done to evaluate the e...
Open access
Research Article10.9734/ajrb/2025/v15i4403
This study investigated the therapeutic potential of Psidium guajava (guava) leaf extract against lead acetate-induced male reproductive dysfunction in albino rats. Twenty-eight male albino rats were randomly divided into 4 groups (n=7 per group): Group A (negative control) recei...
Open access
Research Article10.9734/ajrre/2025/v8i1113
Introduction: Guava (Psidium guajava L.) is a widely consumed fruit in the tropical region and other parts of the world. The leaves, especially, have been reported to have both nutritional and medicinal benefits due to their rich phytochemical content. Studies have reported post-...
Open access
Research Article10.9734/jocamr/2025/v26i5660
Aim: Infertility is a global problem affecting both males and females. It is a condition with psychological, economic, and medical implications resulting in trauma and stress, particularly in a society where there is a strong emphasis on childbearing. The study therefore aims to...
Open access
Research Article10.9734/ajrimps/2022/v11i230186
Action bitters has been seen not to have nephro-toxic effects on the kidney. However, this study evaluated the effects of sachet packaged action bitters on the kidney of apparently healthy subjects. Blood sample was collected from 20 subjects. Basal blood sample and the blood sam...
Open access
Research Article10.9734/ajbgmb/2021/v9i330217
Aim: The study aimed to determine the percentage distribution and frequency of occurrence of P1 blood group antigen among indigenes of Ogoni ethnicity in Rivers State of Nigeria. Study Design: The study was a cross-sectional study conducted on Ogoni indigenes whose first generati...
Recent breakthroughs in gene therapy have ushered in a new era in precision cancer treatment, offering a transformative approach to combating malignancy and high mortality rates. The development of cutting-edge techniques in gene therapy for cancer treatment has led to a more pre...
Open access
Research Article10.9734/ajbgmb/2024/v16i1354
Aim: To evaluate the protective and therapeutic potentials of corn silk extract on gentamicin (CN)-induced nephrotoxicity in albino rats. Study Design: The rats were randomly selected and grouped as follows: Group 1 (NC): Were given only food and water. They served as negative co...
Open access
Research Article10.9734/jocamr/2020/v11i430191
Aim: Evaluate the protective effects of palm oil on renal parameters after dichlorvos toxicity in albino rats. Study Design and Methodology: The study consisted of 3 phases: The acute study which lasted for 24 hours, the sub-acute study which lasted for 14 days and the sub chroni...
Open access
Research Article10.9734/jamps/2020/v22i630175
Aim: To evaluate the anti-oxidant enzymes, lipid peroxidation, lipid profile and liver function in albino rats orally administered tartrazine. Study Design: A total number of 63 female albino rats weighing approximately 0.2 kg were used for this study. The study was divided into...
Open access
Research Article10.9734/ijbcrr/2020/v29i530188
Fidelis Godae Beega, Kemzi Elechi-Amadi, Simeon Christopher Aloy, Sheudeen Abubakar Abiola, Okorocha, CyrilGentle Ugochukwu, Ibioku Elekima & Edna Ogechi Nwachuku·International Research Journal of Oncology·2024
While naturally occurring, heavy metals pose a significant global public health risk due to their extensive utilisation in industrial, residential, and agricultural activities, impacting the health of millions worldwide. Occupational and environmental exposure to these metals thr...
Sheudeen Abubakar Abiola, Adline E. Ben-Chioma, Beega Godae Fidelis, Simeon Christopher Aloy, Anthony Augustine U. & Ibioku Elekima·International Research Journal of Oncology·2024
Breast cancer, a complex and heterogeneous disease, remains a leading cause of global cancer-related morbidity and mortality. According to the World Health Organization 2020 report, breast cancer is responsible for over 685,000 deaths. This comprehensive review explores epigeneti...
Aim: Assess the effect of tartrazine azo dye on atherogenic indices and markers of cardiac injury in albino rats. Study Design: A total number of 63 rats were used for the study. The study was divided into two phases, 1 and 2, which lasted for 30 and 60 days respectively. Phase 1...
Open access
Research Article10.9734/jamps/2020/v22i630179
Aim: To evaluate antioxidants supplementation (selenium and vitamin E) on renal, hepatic and cardiac function markers in alloxan induced diabetes mellitus in Wister rats. Study Design: Rats were randomly assigned into 5 groups with each group consisting of 5 rats. The treatment p...
Open access
Research Article10.9734/jocamr/2020/v9i330143