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Clément L. Inkoto

Publications (15)

Phytochemistry and Pharmacology of Aframomum angustifolium (Sonn.) K. Schum (Zingiberaceae): A Mini Review

Clément L. Inkoto, Koto-Te-Nyiwa Ngbolua, Patrick E. Bokungu, Colette A. Masengo, Jeff B. Iteku, Dorothée D. Tshilanda, Damien S. T. Tshibangu & Pius T. Mpiana · South Asian Research Journal of Natural Products · 2021

According to the World Health Organization (WHO), more than 80% of the population in Africa in general and in the Democratic Republic of the Congo (DRC) in particular, resorts to Traditional Medicine to solve the problem of primary health care. In this study we had reviewed the r...

Open access Research Article

A Mini Review on the Phytochemistry and Pharmacology of Aframomum alboviolaceum (Zingiberaceae)

Clément L. Inkoto, Koto-Te-Nyiwa Ngbolua, Jason T. Kilembe, Colette Masengo Ashande, Félicien L. Lukoki, Dorothée D. Tshilanda, Damien S-T. Tshibangu & Pius T. Mpiana · South Asian Research Journal of Natural Products · 2021

Background and Aims: Given the importance of finding a new Improved Traditional Medicine (ITM) based on medicinal plants, we reviewed the traditional uses, phytochemical composition, biological properties and toxicity of Aframomum alboviolaceum (Zingiberaceae), a plant species wi...

Open access Research Article

Mineral Element Contents and Antisickling Activity of Cyttaranthus congolensis and Hypoxis angustifolia Traditionally Used to Treat Sickle Cell Disease in Kwilu Province, Democratic Republic of the Congo

Jules M. Kitadi, Clément L. Inkoto, Sha-Tshibey Tshibangu, Dorothée Dinangayi Tshilanda, Taba Kalulu, Papy Kawata, Koto-Te-Nyiwa Ngbolua & Pius Tshimankinda Mpiana · International Journal of Biochemistry Research & Review · 2022

The objective of the present study was to determine the composition in mineral elements, the antisickling activity and the osmotic brittleness test, of the twenty three extracts of two plants Cyttaranthus congolensis, Hypoxis angustifolia used in the management of sickle cell dis...

Open access Research Article 10.9734/ijbcrr/2022/v31i10790

Leukocyte Profile of Children Hospitalized in Neonatology Services for Suspected Infection in Kinshasa City, Democratic Republic of the Congo

Rita Bokemposila, Clément L. Inkoto, Alexis Kazamwali, Gaston Mwema, Christian Lobinga, Louise Malonga, Jean Claude Malenga, Thérèse Mbeza, Jean Lambert Gini Ehungu, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Research and Reports in Hematology · 2021

Neonatal infection (NI) remains a public health problem of concern because of its frequency and severity, which is related to the immuno-incompetence of the newborn and the risk of mortality, which is in the order of 10% to 30%. According to the World Health Organization (WHO), 3...

Open access Research Article

Mineral Content and Antisickling Activity of Annona senegalensis, Alchornea cordifolia and Vigna unguiculata Used in the Management of Sickle Cell Disease in the Kwilu Province (Congo, DR)

Jules M. Kitadi, Clément L. Inkoto, Emmanuel M. Lengbiye, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua, K. M. Taba, Blaise M. Mbala, Brigitte Schmitz & Pius T. Mpiana · International Blood Research & Reviews · 2020

Aims: To determine the mineral composition of some plants (Annona senegalensis Pers., Alchornea cordifolia (Schumach. & Thonn.) Müll. Arg. and Vigna unguiculate (L.) Walp.) used in the management of sickle cell disease by traditional practitioners in Kwilu province and to eva...

Open access Research Article 10.9734/ibrr/2020/v11i330131

A Mini Review on the Phytochemistry, Toxicology and Antiviral Activity of Some Medically Interesting Zingiberaceae Species

Clément M. Mbadiko, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Aristote Matondo, Domaine T. Mwanangombo, Etienne M. Ngoyi, Gédéon N. Bongo, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · Journal of Complementary and Alternative Medical Research · 2020

Background: Plants of the Zingiberaceae family namely Curcuma longa, Aframomum melegueta and Zingiber officinale are known for their many biological activities such as the antiviral activity. Aim: To provide an updated knowledge on the phytochemistry, toxicology and antiviral act...

Open access Research Article 10.9734/jocamr/2020/v9i430150

Phytochemistry and Bioactivity of Annona reticulata L. (Annonaceae): A Mini-review

Koto-Te-Nyiwa Ngbolua, Clément L. Inkoto, Gédéon N. Bongo, Lengbiye E. Moke, Lufuluabo G. Lufuluabo, Colette Masengo Ashande, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana · South Asian Research Journal of Natural Products · 2018

Aims: To provide knowledge on phytochemistry and bioactivity of Annona reticulata. Study Design: Multidisciplinary advanced bibliographic surveys, utilization of ChemBioDraw software package and dissemination of the resulted knowledge. Place and Duration of Study: Faculty of Scie...

Open access Research Article

Possible Effect of Aromatic Plants and Essential Oils against COVID-19: Review of Their Antiviral Activity

Damien S. T. Tshibangu, Aristote Matondo, Emmanuel M. Lengbiye, Clément L. Inkoto, Etienne M. Ngoyi, Carlos N. Kabengele, Gédéon N. Bongo, Benjamin Z. Gbolo, Jason T. Kilembe, Domaine T. Mwanangombo, Clément M. Mbadiko, Shetonde O. Mihigo, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · Journal of Complementary and Alternative Medical Research · 2020

Aim: Till now, no specific treatment is available for COVID-19. This work is carried out with the aim of verifying in the literature the antiviral properties of aromatic plants and essential oils that can justify their use against the causative agent of COVID-19, SARS-CoV-2. Meth...

Open access Research Article 10.9734/jocamr/2020/v11i130175

Antiviral Activity, Phytochemistry and Toxicology of Some Medically Interesting Allium Species: A Mini Review

Emmanuel M. Lengbiye, Clément M. Mbadiko, Clarisse M. Falanga, Aristote Matondo, Clément L. Inkoto, Etienne M. Ngoyi, Carlos N. Kabengele, Gédéon N. Bongo, Benjamin Z. Gbolo, Jason T. Kilembe, Domaine T. Mwanangombo, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Shetonde O. Mihigo, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Pathogen Research · 2020

Aims: COVID-19 pandemic affects hundreds of thousands of people worldwide. Since there is no effective treatment, the need of finding alternative methods, which can help to curb this pandemic is urgent. This study aims to collect the information on the virucidal and toxicity prop...

Open access Research Article 10.9734/ijpr/2020/v5i430145

Review on Ethno-botany, Virucidal Activity, Phytochemistry and Toxicology of Solanum genus: Potential Bio-resources for the Therapeutic Management of Covid-19

Koto-Te-Nyiwa Ngbolua, Clément M. Mbadiko, Aristote Matondo, Gédéon N. Bongo, Clément L. Inkoto, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Domaine T. Mwanangombo, Etienne M. Ngoyi, Clarisse M. Falanga, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana · European Journal of Nutrition & Food Safety · 2020

Background and Aim: Condiment plants are not only a source of food, flavors or food additives but also antivirals. The aim of the present work consisted in compiling ethno-botanical, phytochemical, toxicological and biological activities literature data reported on some species o...

Open access Research Article 10.9734/ejnfs/2020/v12i730246

Ocimum Species as Potential Bioresources against COVID-19: A Review of Their Phytochemistry and Antiviral Activity

Dorothée D. Tshilanda, Etienne M. Ngoyi, Carlos N. Kabengele, Aristote Matondo, Gédéon N. Bongo, Clément L. Inkoto, Clément M. Mbadiko, Benjamin Z. Gbolo, Emmanuel M. Lengbiye, Jason T. Kilembe, Domaine T. Mwanangombo, Giresse N. Kasiama, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Pathogen Research · 2020

Aim: The aim of this work was to review literature data reported on some species of the Ocimum genus regarding their phytochemistry and antiviral potential in order to show how Ocimum species might be used in the management of COVID-19. Methodology: Various databases like PubMed,...

Open access Research Article 10.9734/ijpr/2020/v5i430143

Antihelminthic Activity, Phytochemical Profile and Microscopic Features of Ocimum basilicum Collected in DR Congo

Carlos N. Kabengele, Etienne M. Ngoyi, Giresse N. Kasiama, Jason T. Kilembe, Aristote Matondo, Clément L. Inkoto, Emmanuel M. Lengbiye, Clément M. Mbadiko, Jean Jacques D. Amogu, Gédéon N. Bongo, Benjamin Z. Gbolo, Damien S. T. Tshibangu, Koto-Te-Nyiwa Ngbolua, Dorothée D. Tshilanda & Pius T. Mpiana · Asian Journal of Biology · 2020

Aim: The main aim of the present study is to validate the bioactivity of O. basilicum, a medicinal plant traditionally used to treat helminthiasis in DRC. Place and Duration of Study: Department of Chemistry, Science Faculty, University of Kinshasa, between June 2018 and March 20...

Open access Research Article 10.9734/ajob/2020/v10i330110

Aloe vera (L.) Burm. F. as a Potential Anti-COVID-19 Plant: A Mini-review of Its Antiviral Activity

Pius T. Mpiana, Koto-Te-Nyiwa Ngbolua, Damien S. T. Tshibangu, Jason T. Kilembe, Benjamin Z. Gbolo, Domaine T. Mwanangombo, Clément L. Inkoto, Emmanuel M. Lengbiye, Clément M. Mbadiko, Aristote Matondo, Gédéon N. Bongo & Dorothée D. Tshilanda · European Journal of Medicinal Plants · 2020

Aims: A novel β-coronavirus (2019-nCoV) has become a pandemic affecting hundreds of thousands of people worldwide. Since there is no effective treatment, the need of finding alternative methods which can help to curb this pandemic is urgent. This study aims to review the literatu...

Open access Research Article 10.9734/ejmp/2020/v31i830261

Anthelmintic and Antioxidant Activities, Phytochemical Profile and Microscopic Features of Senna alata Collected in the Democratic Republic of Congo

Giresse N. Kasiama, Adam Ikey, Carlos N. Kabengele, Jason T. Kilembe, Etienne N. Matshimba, Juvenal M. Bete, Prudent B. Bahati, Clément L. Inkoto, Paulin K. Mutwale, K. N. Ngbolua, Damien S. T. Tshibangu, Dorothée D. Tshilanda & Pius T. Mpiana · Annual Research & Review in Biology · 2022

Aim: The objective of this study was to determine the phytochemical profile of Senna alata LINN using chemical screening in solution and thin-layer chromatography, and to assess the antioxidant and anthelmintic activities of the plant’s aqueous extracts. Methodology: All the anal...

Open access Research Article 10.9734/arrb/2022/v37i630513

Oleanolic Acid, Ursolic Acid and Apigenin from Ocimum basilicum as Potential Inhibitors of the SARS-CoV-2 Main Protease: A Molecular Docking Study

Aristote Matondo, Jason T. Kilembe, Etienne M. Ngoyi, Carlos N. Kabengele, Giresse N. Kasiama, Emmanuel M. Lengbiye, Clément M. Mbadiko, Clément L. Inkoto, Gédéon N. Bongo, Benjamin Z. Gbolo, Clarisse M. Falanga, Domaine T. Mwanangombo, Daniel O. Opota, Damien S. T. Tshibangu, Dorothée D. Tshilanda, Koto-Te-Nyiwa Ngbolua & Pius T. Mpiana · International Journal of Pathogen Research · 2021

Aim: The present study aims at identifying potential inhibitors from a set of ten compounds from Ocimum basilicum against the SARS-CoV-2 main protease, the chymotrypsin-like protease (3CLpro). Materials and Methods: Computational studies by molecular docking (Autodock tool) were...

Open access Research Article 10.9734/ijpr/2021/v6i230156