Introduction: In Mali, several domesticated edible plants are commonly used for their nutritional and therapeutic properties. But their usage are poorly documented in terms of their chemical composition and pharmacological properties. This highlights the urgent need for ethnobota...
Open access
Research Article10.9734/ejmp/2026/v37i11323
Malaria drug resistance remains one of the greatest challenges to the malaria control program in Mali. Mutation in the Plasmodium falciparum Dihydrofolate Reductase (PfDHFR), a key enzyme in the folate biosynthesis pathway and primary target of antifolate drugs, are knows to indu...
Open access
Research Article10.9734/bji/2025/v29i6813
Cheickna Cissé, Mamadou WELE, Jeffrey G. SHAFFER, Jian Li, Christopher WHALEN, Maria Y. GIOVANNI, Mariam QUINONES, Alia BENKALAH, Doulaye Dembélé, Darrell HURT, Abdoulaye DJIMDE, Karlynn NOBLE, Cheick O. TANGARA, Mahamadoun H. TOURE, Boubacar YALCOUYE, Oudou DIABATE, Abdoulaye DIAWARA, Fatoumata G. FOFANA, Mamadou Sangare, Kangaye DIALLO, Fatumo SEGUN, Mike TARTAKOVSKY, Mahamadou DIAKITE & Seydou O. DOUMBIA·Current Journal of Applied Science and Technology·2025
Introduction: The African Center of Excellence in Bioinformatics and Data-Intensive Science (ACE), a public-private partnership, facilitated by the National Institute of Allergy and Infectious Diseases (NIAID), the National Institutes of Health (NIH), in collaboration with Africa...
Open access
Research Article10.9734/cjast/2025/v44i84599
In our previous work, we established a predictive QSPR (Quantitative Structure-Property Relationship) model for the water/octanol partition coefficient, based on electronic energy (ET), LUMO (Lowest Unoccupied Molecular Orbital) energy, and the energy gap (ΔEgap). This model has...
Open access
Research Article10.9734/irjpac/2026/v27i51030
Background: Malaria remains one of the deadliest infectious diseases globally, causing over 597,000 deaths each year, with Plasmodium falciparum (Pf) responsible for the most severe cases. Sub-Saharan Africa remains the most affected region of the world, the region hosting more t...
Open access
Research Article10.9734/bji/2025/v29i5790
Background: The Rice Yellow Mottle Virus (RYMV) is one of the most significant viral pathogens affecting rice production in Sub-Saharan Africa, leading to yield losses as high as 100% in severely affected areas. In Mali, particularly in the Office du Niger region, RYMV poses a co...
Open access
Research Article10.9734/air/2024/v25i61213
Aims: This work aimed to evaluate the inhibitory effects of Datura innoxia Mill leaf and root extracts on two enzymes involved in the control of diabetes and inflammation. Study Design: The α-amylase and trypsin are two key enzymes involved in the regulation of diabetes and infl...
Open access
Research Article10.9734/arrb/2024/v39i92114
The anti-inflammatory potential was estimated using cancer cells, by quantifying nitrites (NO) based on colorimetric method (Griess reaction) and the cell viability based on the WST-1 assay. The antiproliferative activity was assessed on cell lines (HeLa and MCF-7) using the Cell...
Open access
Research Article10.9734/jalsi/2023/v26i6630
Aim: This study was designed to evaluate tannins extracted from Ziziphus mauritiana as source of potential antimalarial and antimicrobial agents in Mali. Place and Duration of Study: Collection of plant materials, tannins extraction, antibacterial activity evaluation were done at...
Open access
Research Article10.9734/IJBCRR/2018/45335
Fatoumata Gnine FOFANA, Mamadou WELE, Oudou DIABATE, Cheickna Cissé, Abdoulaye DIAWARA, Mahamadoun Haram TOURE, Mahamadou DIAKITE, Seydou O. DOUMBIA & Abdoulaye DJIMDE·Annual Research & Review in Biology·2025
Malaria remains a significant public health concern, especially in endemic regions where increasing drug resistance poses challenges to effective treatment. Vaccine development has emerged as a crucial strategy for malaria control, targeting different stages of the parasite’s lif...
Open access
Research Article10.9734/arrb/2025/v40i92300
Adounigna Kassogué, Soufiana Traore, Sognan Dao, Antoine Dara, Sekou Sissoko, Cheickna Cissé, Kangaye Amadou Diallo, Rokiatou Fané, Atia Traoré, Mamadou WELE & Amadou Hamadoun Babana·Annual Research & Review in Biology·2024
Aims: This study investigates the diversity of endophytic, rhizospheric, and soil bacterial species in agricultural ecosystems in Mali using a targeted metagenomic approach based on 16S rRNA sequencing. The primary aim is to characterize microbial communities and understand their...
Open access
Research Article10.9734/arrb/2024/v39i122179