Malaria drug resistance remains one of the greatest challenges to the malaria control program in Mali. Mutation in the Plasmodium falciparum Dihydrofolate Reductase (PfDHFR), a key enzyme in the folate biosynthesis pathway and primary target of antifolate drugs, are knows to indu...
Open access
Research Article10.9734/bji/2025/v29i6813
Background: Malaria remains one of the deadliest infectious diseases globally, causing over 597,000 deaths each year, with Plasmodium falciparum (Pf) responsible for the most severe cases. Sub-Saharan Africa remains the most affected region of the world, the region hosting more t...
Open access
Research Article10.9734/bji/2025/v29i5790
Background: The Rice Yellow Mottle Virus (RYMV) is one of the most significant viral pathogens affecting rice production in Sub-Saharan Africa, leading to yield losses as high as 100% in severely affected areas. In Mali, particularly in the Office du Niger region, RYMV poses a co...
Open access
Research Article10.9734/air/2024/v25i61213
Aims: This work aimed to evaluate the inhibitory effects of Datura innoxia Mill leaf and root extracts on two enzymes involved in the control of diabetes and inflammation. Study Design: The α-amylase and trypsin are two key enzymes involved in the regulation of diabetes and infl...
Open access
Research Article10.9734/arrb/2024/v39i92114
The anti-inflammatory potential was estimated using cancer cells, by quantifying nitrites (NO) based on colorimetric method (Griess reaction) and the cell viability based on the WST-1 assay. The antiproliferative activity was assessed on cell lines (HeLa and MCF-7) using the Cell...
Open access
Research Article10.9734/jalsi/2023/v26i6630
Aim: This study was designed to evaluate tannins extracted from Ziziphus mauritiana as source of potential antimalarial and antimicrobial agents in Mali. Place and Duration of Study: Collection of plant materials, tannins extraction, antibacterial activity evaluation were done at...
Open access
Research Article10.9734/IJBCRR/2018/45335
Fatoumata Gnine FOFANA, Mamadou WELE, Oudou DIABATE, Cheickna Cissé, Abdoulaye DIAWARA, Mahamadoun Haram TOURE, Mahamadou DIAKITE, Seydou O. DOUMBIA & Abdoulaye DJIMDE·Annual Research & Review in Biology·2025
Malaria remains a significant public health concern, especially in endemic regions where increasing drug resistance poses challenges to effective treatment. Vaccine development has emerged as a crucial strategy for malaria control, targeting different stages of the parasite’s lif...
Open access
Research Article10.9734/arrb/2025/v40i92300
Adounigna Kassogué, Soufiana Traore, Sognan Dao, Antoine Dara, Sekou Sissoko, Cheickna Cissé, Kangaye Amadou Diallo, Rokiatou Fané, Atia Traoré, Mamadou WELE & Amadou Hamadoun Babana·Annual Research & Review in Biology·2024
Aims: This study investigates the diversity of endophytic, rhizospheric, and soil bacterial species in agricultural ecosystems in Mali using a targeted metagenomic approach based on 16S rRNA sequencing. The primary aim is to characterize microbial communities and understand their...
Open access
Research Article10.9734/arrb/2024/v39i122179