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Pharmaceutics

Papers (31)

Evaluation of Phytochemical Profile and Haemolytic Activity of Acacia mearnsii

Francisca Pinto, Fernanda Silva & Antony Barbosa · British Journal of Pharmaceutical Research · 2016

Acacia mearnsii is characterized as a tree with dark green leaves and grow on any types of soil. Its bipinnate leaves with individual leaflets that are used in folk medicine in wound healing, antioxidant, anti-inflammatory and antiviral. Phytochemical tests demonstrated the prese...

Open access Research Article 10.9734/bjpr/2016/30173

Acute and Subacute Toxicity of Sorbitan Monostearate (Span 60) Non-ionic Surfactant Vesicles (Niosomes) in Sprague Dawley Rats

Jankie Satish, Johnson Jenelle, Pinto-Pereira Lexley, Adebayo Amusa & Pillai Gopalakrishna · British Journal of Pharmaceutical Research · 2016

This study was designed to determine the acute and subacute toxicity of non-ionic surfactant, sorbitan monostearate (Span 60) vesicles in a Sprague Dawley rat model. The primary aim was to investigate the acute toxicity of Span 60 niosomes after single intraperitoneal (IP) as wel...

Open access Research Article 10.9734/bjpr/2016/30380

Acute and Subchronic Toxicity Studies of Aqueous, Methanolic and n-Hexane Root Extracts of Curcuma longa L. on Albino Rats

A Mohammed, A Wudil, A Alhassan, I Muhammad, A Idi & Y Abdulmumin · British Journal of Pharmaceutical Research · 2016

Introduction: The rapid increase in the use and consumption of herbal remedies worldwide has been stimulated by several factors, including the notion that most herbal products are safe and effective. Aim: This work was designed to evaluate the acute and subchronic toxicity of ora...

Open access Research Article 10.9734/bjpr/2016/27237

Formulation and Evaluation of Fluconazole Mucoadhisive Vaginal Tablets

Gamal Mahours, Abdelrahman Sherif, Diaa Shaaban & Gamal Shazly · British Journal of Pharmaceutical Research · 2016

The Mucoadhesive drug delivery system has occupied an important place in the field of pharmaceutical research. Mucoadhesive tablets prolong the residence time of the drug at the site of application and provide extended therapeutic effect. Mucoadhesive tablets have been prepared f...

Open access Research Article 10.9734/bjpr/2016/30629

Development and Evaluation of the Binding Properties of Raphia hookeri (Fam. Palmaceae) Gum in Pharmaceutical Tablet Formulations

Stephen Majekodunmi & Stanley Makper · British Journal of Pharmaceutical Research · 2016

Aims: This study was aimed to evaluate the potential of using Raphia hookeri gum as a binder in tablet formulations. Study Design: Extract of Raphia hookeri gum was investigated as a binding agent in paracetamol tablet formulation in comparison with gelatin BP as standard binder....

Open access Research Article 10.9734/bjpr/2016/28610

Anti-angiogenic Potential of Mentha longifolia (Horse Mint): Chlorioallantoic Membrane Assay

Nazia Tabassum, Uzma Saleem & Bashir Ahmad · British Journal of Pharmaceutical Research · 2016

Inhibition of angiogenesis is one of the mechanisms of action of anticancer drugs. The current study was designed to probe into anti-angiogenic effect of Mentha longifolia by employing Chorioallantoic membrane assay. White leghorn fertilized eggs were used in the study (n=10). On...

Open access Research Article 10.9734/bjpr/2016/31083

Comparative Evaluation of Poly Herbal Formulation from Traditionally Used Eritrean Medicinal Plants against Pathogenic Microorganisms

Jeevan Kaushik, Nuredin Mohammedkassm, Dawit Mebrahtu, Atul Kaushik, Merhawi Kidane, Meron Solomon, Michael Teklemariam & Salih Mohammedbrhan · British Journal of Pharmaceutical Research · 2016

Aim: The present study was taken to investigate the in vitro anti-microbial activity of Poly herbal formulation (PHF) of Schinus molle, Rhamnus prinoides, Grewia ferruginea, Achyranthes aspera against different human pathogenic strains. Methods: Leaves of selected plants were ext...

Open access Research Article 10.9734/bjpr/2016/30059

Artemisia annua L.- Vernonia amygdalina Del: A Potential Herbal Artemisinin Combination Treatment against Malaria

Nambejja Cissy, Ogwang Engeu, Onegi Berna, Anyama Norbert & Matu Esther · British Journal of Pharmaceutical Research · 2016

Aim of Study: The aim of the study was to determine the potential of Vernonia amygdalina - Artemisia annua combination as a possible herbal artemisinin combination treatment of malaria. Place and Duration of Study: Study was conducted at Natural Chemotherapeutics Research Institu...

Open access Research Article 10.9734/bjpr/2016/29555

Simultaneous Determination of Ternary Mixture of Aspirin, Caffeine and Orphenadrine Citrate by Simple RP-TLC Spectrodensitometric Method

Mohammed Gamal, Nouruddin Ali, Mohammed Elghobashy & Mohammed Abdelkawy · British Journal of Pharmaceutical Research · 2016

Aims: A simple TLC Spectrodensitometric method was developed for analysis of Orphenadrine Citrate (OR), Caffeine (CAF) and Aspirin (ASP) either in pure form or in their pharmaceutical preparations. Study Design: Validation study. Methodology: In this method, The three drugs were...

Open access Research Article 10.9734/bjpr/2016/31194

Lubricating Properties of Co-processed Coconut Oil in Paracetamol Tablets Formulation

Stephen Majekodunmi & Eyituoyo Lori · British Journal of Pharmaceutical Research · 2016

Objective: Lubricants are additives which reduce friction and so essential components of drug formulation. This piece of work was initiated to evaluate coconut oil as a co-processed lubricant in the formulation and compression of paracetamol tablets in comparison with magnesium s...

Open access Research Article 10.9734/bjpr/2016/31379

Free Radicals Scavenging and Protein Protective Property of Ocimum sanctum (L)

Anand Keshari, Atul Srivastava, Akhilesh Verma & Ragini Srivastava · British Journal of Pharmaceutical Research · 2016

Ocimum sanctum (L) is a well-known herbal plant used for the treatment of bronchitis, malaria, diarrhea, dysentery, skin disease, arthritis, eye diseases and insect bites. It is proposed to have anticancer, antidiabetic, antifungal, antimicrobial, cardio protective, analgesic and...

Open access Research Article 10.9734/bjpr/2016/31445

Synthesis of Silver Nanoparticles by Sodium Borohydride Reduction Method: Optimization of Conditions for High Anti-staphylococcal Activity

Ifeanyi Nzekwe, Chukwuma Agubata, Chukwuebuka Umeyor, Ifeanyi Okoye & Chidalu Ogwueleka · British Journal of Pharmaceutical Research · 2016

Aim: The aim of this research was to optimize the reaction conditions for the production of silver nanoparticles sufficiently bioactive for incorporation into pharmaceutical gels. Methods: Silver nanoparticles were prepared by silver nitrate-sodium borohydride reduction method un...

Open access Research Article 10.9734/bjpr/2016/30324

Slow-Stroke Back Massage Intervention for Relieving Postpartum Fatigue in Primiparous Mothers after a Natural Delivery: A Randomized Clinical Trial in Zabol

Zahra Moradi, Amin Aliabadi, Ali Rahdari, Firoozeh Moghaddam, Faeze Sanchooli & Niloofar Heydari · British Journal of Pharmaceutical Research · 2016

Introduction: Fatigue is one of the most prevalent phenomenon reported by post-partum mothers and have various effects on their physical, emotional and cognitive aspects. Back massage relaxation techniques are one of the most important non-pharmacological interventions to prevent...

Open access Research Article 10.9734/bjpr/2016/31509

GCMS Analysis of Leaf and Salt Stress Callus of Eggplant (Solanum melongena L.)

A Kalimuthu, V Chinnadurai, Y Juliet & R Prabakaran · British Journal of Pharmaceutical Research · 2016

In the present study, the leaf explant cultured on a MS medium supplemented with BAP (4.44 μM) + NAA (0.98 μM) had the ability to induce more amount of green and friable callus. The 40 days old best grown callus was sub cultured on the combination of various concentrations of BAP...

Open access Research Article 10.9734/bjpr/2016/30425

Stability-Indicating RP-UPLC Method Development and Validation for the Process Related Impurities of Nebivolol and Structural Characterization of Its Forced Degradation Products by LC-MS/MS

Prasad Kancherla, Pallavi Alegete, Srinivas Keesari, Bhavyasri Khagga, Sridhar Siddiraju, Mukkanti Khagga & Parthasarathi Das · British Journal of Pharmaceutical Research · 2016

The present study reports the development and validation of a stability-indicating reverse phase ultra performance liquid chromatographic method for the determination of nebivolol (NEB) in the presence of its process related impurities in bulk drugs and also demonstrates the stru...

Open access Research Article 10.9734/bjpr/2016/31354