The British Journal of Pharmaceutical Research (ISSN: 2231-2919) was a peer-reviewed, open-access scientific publication by Sciencedomain International that covered all areas of pharmaceutical science and research. Published original research papers, reviews, and short communications spanning clinical pharmacy, medicinal chemistry, pharmacognosy, toxicology, pharmacokinetics, and drug legislation.
Novel, less toxic, more effective catalysts were used to synthesize various flavones under auto clave conditions. Substituted o- hydroxyl acetophenones and benzaldehydes were reacted in-presence of 2, 4, 6-trimethylpyridine, a pinch of TiCl4 and yielded chalcones. Equimolar ratio...
Open access
Research Article10.9734/bjpr/2016/15884
The aqueous distillate (arka) of Boerhaavia diffusa was prepared and investigated qualitatively for TLC. The following work constitutes the enrichment of constituents present in the aqueous distillate (arka) by partition technique using various solvents such as toluene and ethyl...
Open access
Research Article10.9734/bjpr/2016/19399
Background: In addition to the problems of resistance to commonly used antibiotics, toxicity depicts the state of adverse effects caused by the interaction of toxicants with cells. Similarly, blood components are exposed to significant concentrations of toxic compounds as they fo...
Open access
Research Article10.9734/bjpr/2016/19971
The aim of this work was to find an alternative to chemical fungicides currently used in the control and prevention of activities of toxigenic Aspergillus flavus, A. parasiticus and A. ochraceus in food and feed. The antifungal activity of extracts of five medicinal plants used in...
Open access
Research Article10.9734/bjpr/2016/20390
Aim: This study was designed to evaluate the possible modulatory effect of vitamine E on tacrolimus (FK506)-induced renal injury in rats. Methods: Twenty-four male Wistar rats (6 animals in each group) were used in this study. The first group (Control) received normal saline intr...
Open access
Research Article10.9734/bjpr/2016/21684
Aim: A comparative evaluation of the physicochemical and in vitro dissolution properties of metformin hydrochloride tablet brands sampled in five cities in Ghana was undertaken to assess their pharmaceutical equivalence. Place and Duration of Study: Department of Pharmaceutics, K...
Open access
Research Article10.9734/bjpr/2016/21862
Aims: Highly Active Antiretroviral Therapy (HAART) is associated with metabolic complications. An unexpected extension of functional implications of melatonin, the neuro-hormone synthetized during the night, has been reported on the development of type 2 diabetes, sleep disturban...
Open access
Research Article10.9734/bjpr/2016/29474
Omeprazole (OPZ) efficiently suppresses acid secretion in the parietal cells of the stomach. It is widely recommended as proton pump inhibitor (PPI) in Egypt. Presence of many products containing omeprazole available in the Egyptian market raises questions of generic substitution...
Open access
Research Article10.9734/bjpr/2016/29952
Aim: Morus mesozygia is a specie of the Morus family in Africa that is traditionally used for the treatment of rheumatism. Until this moment, there is no available literature on the scientific evidence of the in vivo anti-inflammatory effects. The aim is to determine the safety o...
Open access
Research Article10.9734/bjpr/2016/28746
The focus of this research work was to develop a melt granulation technique to enhance solubility, dissolution rate and associated flowability concerns of Ibuprofen. Hydrophilic excipients like xylitol and lactose anhydrous were added to the binary mixture of conventional low mel...
Open access
Research Article10.9734/bjpr/2016/29048