Nigella sativa is considered as a miracle drug. Although there is a list of diseases which can be treated by it but role of N.s seeds in treatment of diabetes is substantially important. There are multiple classes of antidiabetic agents which ameliorate the hyperglycemia by diffe...
Open access
Research Article10.9734/bjpr/2016/30684
Aims: This study was aimed to evaluate the potential of using Raphia hookeri gum as a binder in tablet formulations. Study Design: Extract of Raphia hookeri gum was investigated as a binding agent in paracetamol tablet formulation in comparison with gelatin BP as standard binder....
Open access
Research Article10.9734/bjpr/2016/28610
Inhibition of angiogenesis is one of the mechanisms of action of anticancer drugs. The current study was designed to probe into anti-angiogenic effect of Mentha longifolia by employing Chorioallantoic membrane assay. White leghorn fertilized eggs were used in the study (n=10). On...
Open access
Research Article10.9734/bjpr/2016/31083
Aims: This paper mentions of the investigation of the enzymes binding to Voglibose and the choice of the enzyme which is suitable for drug enzyme interaction as used in biosensing. Voglibose is an antidiabetic drug which is reactive and hence used in very low concentrations. The...
Open access
Research Article10.9734/bjpr/2016/30369
Aim: The present study was taken to investigate the in vitro anti-microbial activity of Poly herbal formulation (PHF) of Schinus molle, Rhamnus prinoides, Grewia ferruginea, Achyranthes aspera against different human pathogenic strains. Methods: Leaves of selected plants were ext...
Open access
Research Article10.9734/bjpr/2016/30059
Aim of Study: The aim of the study was to determine the potential of Vernonia amygdalina - Artemisia annua combination as a possible herbal artemisinin combination treatment of malaria. Place and Duration of Study: Study was conducted at Natural Chemotherapeutics Research Institu...
Open access
Research Article10.9734/bjpr/2016/29555
Aims: This study was undertaken to characterize the bioactive constituents of Apium leptophyllum fruits and to evaluate their cytotoxicity, anti-inflammatory and alpha-amylase inhibitory effects. Study Design: Isolation and identification of the phytochemicals from the petroleum...
Open access
Research Article10.9734/bjpr/2016/30289
Drug delivery to the posterior segment of the eye is a significantly challenging task due to the underlying physiological, anatomical and metabolic constraints. Delivery of drugs through ophthalmic route is significantly hindered by multiple physiological processes including pote...
Open access
Research Article10.9734/bjpr/2016/30601
Aims: A simple TLC Spectrodensitometric method was developed for analysis of Orphenadrine Citrate (OR), Caffeine (CAF) and Aspirin (ASP) either in pure form or in their pharmaceutical preparations. Study Design: Validation study. Methodology: In this method, The three drugs were...
Open access
Research Article10.9734/bjpr/2016/31194
Purpose: To develop a highly selective, reproducible & precise rugged bio analytical method for estimation of Bortezomib (BTZ), “A Protease Inhibitor” in human plasma by validating the developed method in accordance to US-FDA guidelines. Methodology Envisaged: BTZ D3 was used as...
Open access
Research Article10.9734/bjpr/2016/30565
The Phytochemical and antibacterial activities of Calotropis procera Leaf Organic Fractions were tested against vancomycin and methicliin resistant bacteria isolated from wound patients in Ondo State Specialist Hospital. The bacterial isolates are; Staphylococcus aureus, Escheric...
Open access
Research Article10.9734/bjpr/2016/30974
Seed oils of watermelon, unripe and ripe pawpaw were extracted and analyzed for their fatty acid composition using GC/EIMS, phenolic content and antioxidant potential using free radical scavenging effect on 2, 2-diphenyl-2-picrylhydrazyl (DPPH) radical. Watermelon seed oil has ei...
Open access
Research Article10.9734/bjpr/2016/27974
Objective: Lubricants are additives which reduce friction and so essential components of drug formulation. This piece of work was initiated to evaluate coconut oil as a co-processed lubricant in the formulation and compression of paracetamol tablets in comparison with magnesium s...
Open access
Research Article10.9734/bjpr/2016/31379
Ocimum sanctum (L) is a well-known herbal plant used for the treatment of bronchitis, malaria, diarrhea, dysentery, skin disease, arthritis, eye diseases and insect bites. It is proposed to have anticancer, antidiabetic, antifungal, antimicrobial, cardio protective, analgesic and...
Open access
Research Article10.9734/bjpr/2016/31445
Fipronil (FPN) is a wide-spectrum insecticide and has been extensively used in agriculture since 1990s. The current study was deliberated to inspect the retrograde effects of exposure to the FPN on the hepatic tissues of male rats at concentration 10 mg/L in drinking water for 30...
Open access
Research Article10.9734/bjpr/2016/23660