Aims: This study was undertaken to evaluate the effectiveness of behavioral modulation of C. cassia extract against Haloperidol induced Parkinson’s disease (PD) in albino mice. Study Design: The study used animal models to test the effect of Haloperidol in development of PD and e...
Open access
Research Article10.9734/bjpr/2016/29286
Odontonema is a group of tropical plant species used in folklore medicine because of its wide range of pharmacological properties. These plants are known to be anti-bacterial, anti-inflammatory, anti-hypertensive, anti-viral, hepatoprotective, sedative and anti-oxidant. Furthermo...
Open access
Research Article10.9734/bjpr/2016/29877
Self-medication involves the use of medicinal products by the individuals to treat self-recognized diseases or symptoms or the intermittent or continuous use of medication prescribed by a physician for chronic or recurrent disease or symptoms. Self-medication also involves acquir...
Open access
Research Article10.9734/bjpr/2016/30333
Background: Penisetum glaucum is one of the earliest indigenous food crops in East Africa. Pearl millet contains numerous phytocompounds. Isolation and characterization of secondary metabolites from pearl millet and evaluation of their bioactivity is necessary. These will act as...
Open access
Research Article10.9734/bjpr/2016/28434
Objective: To determine the infective dose of Staphylococcus aureus (ATCC 29213) and Pseudomonas aeruginosa (ATCC 27853) in Sprague Dawley rats, when the inoculum is injected via the intraperitoneal route. Design and Methods: In interest of animal welfare and to reduce the number...
Open access
Research Article10.9734/bjpr/2016/29932
Aims: To perform anti-microbial activity guided isolation and to characterize compound(s) from fruit pulp (extracts) of Azanza garckeana. Place and Duration of Study: Department of chemistry, University of Agriculture, Makurdi, Nigeria, and University of Strathclyde in Scotland,...
Open access
Research Article10.9734/bjpr/2016/30152
Background: Alchornea laxiflora is a medicinal plant with immense health benefits. Aim: To verify the protective effects of methanol extract of Alchornea laxiflora (MEAL) leaf on hepatotoxicity and reproductive toxicity induced by CCl4. Settings and Design: Extraction and adminis...
Open access
Research Article10.9734/bjpr/2016/29807
Aim: To prevent proliferation of mosquito borne diseases, to improve quality of life, mosquito control is essential. Research was aimed to find alternative eco-friendly and bio-degradable strategies in mosquito control at the larvae stage. Hence an attempt was made to study the l...
Open access
Research Article10.9734/bjpr/2016/29878
Several pathogenic bacteria are developing antibiotic resistance. Recovery from multidrug resistant (MDR) infections is a problematic issue and requires a multiple treatment with broad-spectrum antibiotics which are less effective, more toxic and more expensive. Silver nanopartic...
Open access
Research Article10.9734/bjpr/2016/30525
Contemporary civilization is facing more than thousands of disorders accompanied with free radicals. Antioxidants from edible and non-edible mushrooms are gaining importance to fight these disorders. The current investigation was intended to evaluate antioxidant and cytotoxic eff...
Open access
Research Article10.9734/bjpr/2016/30594
Introduction: Recently there has been a great deal of interest in the health benefits of phytochemicals, particularly prenylated and allylated flavonoids. Chalcones (1, 3-diaryl-2-propen-1-ones) and their derivatives are important intermediates of the flavonoid synthetic pathway....
Open access
Research Article10.9734/bjpr/2016/28243
Acacia mearnsii is characterized as a tree with dark green leaves and grow on any types of soil. Its bipinnate leaves with individual leaflets that are used in folk medicine in wound healing, antioxidant, anti-inflammatory and antiviral. Phytochemical tests demonstrated the prese...
Open access
Research Article10.9734/bjpr/2016/30173
This study was designed to determine the acute and subacute toxicity of non-ionic surfactant, sorbitan monostearate (Span 60) vesicles in a Sprague Dawley rat model. The primary aim was to investigate the acute toxicity of Span 60 niosomes after single intraperitoneal (IP) as wel...
Open access
Research Article10.9734/bjpr/2016/30380
Introduction: The rapid increase in the use and consumption of herbal remedies worldwide has been stimulated by several factors, including the notion that most herbal products are safe and effective. Aim: This work was designed to evaluate the acute and subchronic toxicity of ora...
Open access
Research Article10.9734/bjpr/2016/27237
The Mucoadhesive drug delivery system has occupied an important place in the field of pharmaceutical research. Mucoadhesive tablets prolong the residence time of the drug at the site of application and provide extended therapeutic effect. Mucoadhesive tablets have been prepared f...
Open access
Research Article10.9734/bjpr/2016/30629