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All published articles 379

Knowledge of Sickle Cell Disease among University Students in Port Harcourt

Tamuno-Opubo Abiye, Stanley Rosemary Oluchi, Ezeugwu Sampson Ibekwe & Chimenem Simple Tamuno-Opubo · International Blood Research & Reviews · 2020

Background: Sickle Cell Disease (SCD) is a hereditary haemoglobinopathy that has been related with significant mortality in Nigeria. Knowledge on cause, prevention and risk factors are important for adequate control of the occurrence of SCD. Methods: A cross sectional study on th...

Open access Research Article 10.9734/ibrr/2020/v11i130122

Haemostatic Effects of Ethanolic Extracts of Amaranthus hybridus on Wistar Rats

B. C. Chinko & F. S. Amah-Tariah · International Blood Research & Reviews · 2020

Introduction: Haemostasis refers to the arrest of bleeding due to vascular damage and involves the intrinsic and extrinsic coagulation pathways which converge at the point of fibrin activation to stop or minimize blood loss. Amaranthus hybridus contains a while range of nutrition...

Open access Research Article 10.9734/ibrr/2020/v11i130121

Kell Blood Group Antigens Not Found in Indigenes of Ogoni Ethnic Group of Rivers State, Nigeria

Serekara Gideon Christian, Evelyn Mgbeoma Eze, Anthony Chijioke Uzoanya Ezimah & Fiekumo Igbida Buseri · International Blood Research & Reviews · 2020

Aim: The aim of the study was to determine the frequency of occurrence and percentage distribution of Kell blood group antigens in indigenes of Ogoni ethnic group of Rivers State, Nigeria. Study Design:  This was a cross-sectional study carried out among indigenes of Ogoni whose...

Open access Research Article 10.9734/ibrr/2020/v11i130119

Distribution of ABO, Rhesus D and Subgroups of ABO among Blood Donors in Sokoto, North Western Nigeria

A. B. Ibrahim, H. Attahiru, O. Erhabor, P. F. Udomah, A. Yakubu, H. A. Buhari, H. M. Ahmed, F. U. Onuigwe, D. Isah, M. U. Kalgo & U. Abubakar · International Blood Research & Reviews · 2020

ABO, Rhesus D and subgroups of ABO are highly immunogenic and are the common cause of antibody production in mismatched blood transfusions, haemolytic transfusion reaction and maternal alloimmunization. The aim of this study was to determine the occurrence of ABO, Rh D and subgro...

Open access Research Article 10.9734/ibrr/2020/v11i130120

Beta Thalassemia Major: Overview of Molecular Etiology, Pathophysiology, Current and Novel Therapeutic Approaches

S. El Kababi, B. El Khalfi, K. El Maani & A. Soukri · International Blood Research & Reviews · 2020

Major beta thalassemia is a severe form of thalassemia caused by the alteration of two beta globin genes resulting in a defective synthesis of hemoglobin. It is characterized by chronic severe anemia, ineffective erythropoiesis (IE) and iron overload. However although the thransf...

Open access Research Article 10.9734/ibrr/2019/v10i230118

L-PRF Membrane (Fibrin Rich in Platelets and Leukocytes) and Its Derivatives (A-PRF, i-PRF) are Helpful as a Basis of Stem Cells in Regenerative Injury Treatment: Trial Work on the Horse

Alessandro Crisci, Maria Chiara Barillaro, Giovanni Lepore & Federica Cardillo · International Blood Research & Reviews · 2020

Developing a multidisciplinary field of tissue engineering aims to recover, improve or supplant typically damaged or missing tissues for a collection of conditions brought about by trauma, malady and old age. To guarantee that tissue engineering techniques are generally relevant...

Open access Research Article 10.9734/ibrr/2019/v10i230117

Blood Donation Practices of Tertiary Level Students in South Eastern Nigeria: Prevalence and Determinants

Chukwuma B. Duru, Uche R. Oluoha, Anthony C. Iwu, Chinyere M. Aguocha, Ikechi Ohale, Emmanuel N. Ndukwu, Ernest Nwaigbo & Nnamdi P. Okafor · International Blood Research & Reviews · 2020

Introduction: Safe and adequate blood donation is critical in saving millions of lives annually. In many developing including Nigeria, there is paucity of blood donors. Aim: In this study, we assessed the blood donation practices of tertiary level students in Imo State, South Eas...

Open access Research Article 10.9734/ibrr/2019/v10i230116

The KAPP Study of Malaria and its Prevalence amongst Boarding School Students in Gboko Local Government Area of Benue State, Nigeria

N. Amagu, V. U. Obisike & E. U. Amuta · International Blood Research & Reviews · 2019

Malaria is a life-threatening parasitic disease caused by a protozoan of the genus Plasmodium and is one of the most important parasitic diseases of man globally especially in sub-Saharan Africa. This research was done to assess malaria infection and its relationship with the kno...

Open access Research Article 10.9734/ibrr/2019/v10i230115

Glutathione and Bilirubin Concentrations as Markers of Oxidative Stress Measured among Sickle Cell Anaemia Subjects Attending University of Calabar Teaching Hospital, Calabar Nigeria

E. E. Onukak, E. C. Akwiwu, J. O. Akpotuzor, A. O. Okafor & A. E. Onukak · International Blood Research & Reviews · 2019

Aims: This study aimed at examining the oxidative stress level of sickle cell anaemia subjects using glutathione and bilirubin levels as markers as well as the red cell parameters. Study Design: Case-control study. Place and Duration of Study: University of Calabar Teaching Hospi...

Open access Research Article 10.9734/ibrr/2019/v10i230114

Evaluation of Impact of Some Selected Plants on Haematological Parameters of Testosterone and Estradiol Induced Benign Prostatic Hyperplasia Adult Male Rats

Melvin Nnaemeka Ugwu, Atamgba Agbor Asuk, Mbeh Ubana Eteng & Edward Odey Emuru · International Blood Research & Reviews · 2019

Background: Benign prostate hyperplasia (BPH) is an age-related disease of unknown etiology, characterized by prostate enlargement. The effect of Prosopis africana (PA), Vernonia amydalina (VA) and Ocimum gratissmum (OG), plant extracts on haematological parameters of BPH animal...

Open access Research Article 10.9734/ibrr/2019/v10i130113

Factors Affecting Ferritin Level in Children of 6 to 59 Months in the Eastern Region of Cameroon

Sylvie D. Agokeng, Claude T. Tayou, Jules Clement N. Assob & Anna L. Njunda · International Blood Research & Reviews · 2019

Aim: Ferritin reflects total iron storage and is also the first laboratory index to decline with iron deficiency. It may be less accurate in children with infectious or inflammatory conditions as an acute phase reactant. Considering the fact that Cameroonian children live in malar...

Open access Research Article 10.9734/ibrr/2019/v10i130112

Nocardiosis Associated with Novel Agents at Relapsed Multiple Myeloma: Case Series

Atakan Turgutkaya, Zahit Bolaman, Emel Ceylan, Murat Telli, Berna Gültekin Korkmazgil, Can Karaman & Irfan Yavasoglu · International Blood Research & Reviews · 2019

Nocardiosis is a gram positive bacterial infection caused by aerobicactinomycetes. It’s nonspesific presentation and radiographic findings usually make it undiagnosed with highly fatal outcomes. The patients with intracelluler defects are prone to nocardiosis. Multiplemyelom(MM)...

Open access Research Article 10.9734/ibrr/2019/v10i130111

Serum Electrolytes and Red Blood Cell Membrane Potential of Hypertensive Patients

Nwadike Constance, Nosiri Chidi Ijeoma, Eze Adindu, Onyeabo Chimaraoke, Ezekwe Ahamefula Sunday & Onyejiekwe Catherine · International Blood Research & Reviews · 2019

Serum electrolyte and red blood cell membrane potential of hypertensive patients in Owerri metropolis were investigated. A total of 50 volunteer subjects were used for the study.  Thirty (30) of the volunteer subjects were hypertensive subjects and were used as test subjects; whi...

Open access Research Article 10.9734/ibrr/2019/v10i130110

Biochemical and Hematological Impact of Hepatitis C Virus (HCV) on Human Immunodeficiency Virus (HIV) Infected Persons on Antiretroviral Drugs (ARDs) in Nigeria

Ya’aba Yakubu, Mohammed Shehu Busu, Nfongeh Joseph Fuh, Olatunji Kazeem Toyosi, Abubakar Aisha, Usoroh Mary, Daniel Oluwaseun Christiana & Abdulmumin Adam Raji · International Blood Research & Reviews · 2019

Introduction: Biochemical and hematological abnormalities are among most common clinico-pathological manifestations of HIV/AIDS infected persons on antiretroviral drugs (ARDs). Hepatitis C Virus (HCV) infection are known to influence progression and management of HIV infection. D...

Open access Research Article 10.9734/ibrr/2019/v10i130109

Assessment of Blood Storage Effect Using CPDA-1 on Packed Cell Volume, Oxyhaemoglobin and Methaemoglobin in Different ABO/Rhesus Blood Types

Serekara Gideon Christian, Evelyn Mgbeoma Eze & Ndueghe Ebenezer Nkom · International Blood Research & Reviews · 2019

Aims: The aim of this study is to determine the effect of blood storage using CPDA-1 on packed cell volume, methaemoglobin and oxyhaemoglobin in different ABO/Rhesus blood types donated by some residents of Port Harcourt, Rivers State, Nigeria. Study Design: This is a comparative...

Open access Research Article 10.9734/ibrr/2019/v9i430108