Antidiabetic Activity of Aerial Parts and Seeds of Purslane (Portulaca oleracea) on Diabetic Rats

Abstract

This study has been proposed to study the effect of aerial parts and seeds of purslane on diabetic rats. Chemical composition, phenolic compounds and fatty acids of purslane and seeds powder were determined. A biological experiment was performed using 30 male albino rats. The rats were divided into six groups (five in group) and the duration of experiment was 8 weeks. Normal control (G1) non- diabetic rats fed on the basal diet, diabetic control (G2) diabetic rats fed on the basal diet only, the other groups of diabetic rats fed on basal diet supplemented with purslane (5 and 10%) and  seeds (5 and 10%). The results of biological experiment indicated that adding of purslane and seeds to basal diet for diabetic rats, led to improvement in liver and kidney functions and an increase in body weight and HDL cholesterol and decrease blood glucose, TC, TG, LDL cholesterol, v-LDL cholesterol comparing to those of diabetic rats fed on basal diet only diabetic control. Purslane (5 and 10%) and seeds (5 and 10%) were added to burger as a replacement of fat. The results of sensory evaluation indicated that all sensory properties of the burger prepared with purslane and seeds were acceptable. Through the results of this study, we recommend the possibility of using purslane and seeds to prevent and reduce the symptoms caused by diabetes.