Therapeutic Effects of Phytochemicals of Brassicaceae for Management of Obesity
Abudukadeer Kuerban, Soonham Sami Yaghmoor, Yaaser Q. Almulaiky, Youssri Ahmed Mohamed, Syed Shoeb Iqbal Razvi, Mohammed Nihal Hasan, Said Salama Moselhy, Ayat B. Al-Ghafari, Hadeel M. Alsufiani, Taha A. Kumosani, Abdulrahman L-AL-Malki
Journal of Pharmaceutical Research International · pp. 1–11 · Published 8 Nov 2017
10.9734/JPRI/2017/37617Abstract
Cruciferous vegetables are rich in glucosinolates, carotenoids, chlorophylls and ascorbic acid which play a major role in the modulation of lipid metabolism and are therefore involved in the lowering of total cholesterol levels in the blood. Cruciferous diet has an inverse relationship with the obesity which has been attributed to the indoles and isothiocyanates derived from the glucosinolates, such as indole-3-carbinol (I3C) and sulforaphane. Obesity and overweight still remain one of the leading causes of “preventable” deaths worldwide exerting a great deal of strain on the healthcare systems. It is ironic to note that there are nearly 100 drugs available in the market for the obesity related diseases like hypertension, but only 6 medications have been approved for the treatment of obesity in the long run. Since obesity is a chronic and permeant disease, it puts an individual to a risk of 30 more chronic diseases like hypertension, type 2 diabetes, cancers, degenerative joint diseases and cardiovascular diseases. Hence, there is a desperate need to find an alternative supporting strategy to support the current medications. In this communication, we have explored the role of phytochemicals from cruciferous diet in exerting hypolipidemic effects, which may open up nascent avenues for therapeutic intervention to tackle obesity.
Cited by 13
Samnhita Raychaudhuri, Si Fan, Olivia Kraus · PLOS ONE · 2021
Hüseyin Emre Aydın, Muhammed Aydın, Özge Aydın · Uludağ Üniversitesi Tıp Fakültesi Dergisi · 2024
Esraa Almugrabi, Antonina Anatolievna Mostyakova, Olga Arnoldovna Timofeeva · Agrarian Scientific Journal · 2025
Barbara Pipan, Mohamed Neji, Vladimir Meglič · 2023
Maryam A. Al-Ghamdi, A. AL-Enazy, E.A Huwait · Brazilian Journal of Biology · 2023
Waseem Khalid, Iqra, Fareed Afzal · International Journal of Food Properties · 2023
Erika Ortega-Hernández, Marilena Antunes-Ricardo, Luis Cisneros-Zevallos · Plants · 2022
Waseem Khalid, Ali Ikram, Muhammad Tahir Nadeem · Journal of Food Processing and Preservation · 2023
Iahtisham-Ul-Haq, Kanza Aziz Awan, Urwa Tariq · Superfoods · 2026
E. Almugrabi, I. V. Galiev, R. P. Khakimzyanova · Vegetable crops of Russia · 2024
Related research
- The Prevalence of Prediabetes and Its Association with Metabolic Syndrome and Insulin Resistance in the Central Indian Population — shares topic coverage
- Cholesterol and Fatty Acid Profiles of Some Bird Egg Varieties: Possible Health Implications — shares topic coverage
- Effect of Estradiol Valerate on Serum Biochemical Profiles in Aged Female Albino Rats — shares topic coverage
- The Effect of Pleurotus tuberregium (An Oyster Mushroom) Sclerotia on the Weight, Protein Content and Lipid Profile of Broiler Chickens — shares topic coverage
- Total Cholesterol and Triglycerides in Unmarried Males and Females of Azad Jammu and Kashmir, Pakistan — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
13
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.