Statins and thiazides which are widely prescribed for the treatment of hyperlipidemia and hypertension play an important role in bone metabolism and may have potential therapeutic implications for osteoporosis. Moreover, concomitant use of statins and thiazides may offer additiv...
Open access
Research Article10.9734/JPRI/2018/40943
Taha A. Kumosani, Khadijah Saeed Balamash, Hanaa Ghashlan, Youssri Ahmed Mohamed, Othman A. S. Baothman, Mustafa Zeyadi, Soonham Sami Yaghmoor, Areej H. Alyahiby, Rana R. AL-Rasheed, Wafa Y. Alturkistani, Tahani M. Alghamdi, Maryam H. AL-Zahrani & Said Salama Moselhy·Journal of Pharmaceutical Research International·2017
Background: Marine microorganisms such as algae were identified a rich sources of biologically active compounds. This study was designed to explore the in vitro antioxidant, anti-apoptotic and anti proliferative activities of different algae [Gracilaria dendroides (GD), Dictyota...
Open access
Research Article10.9734/JPRI/2017/38089
Ashgan Mohammed K. Al-Manzlawi, Khalid O. Abulnaja, Mazin A. Zamzami, Taha A. Kumosani, Qari M., Alaama Mohammed Nabil, Alaa Adel Aljehani, Suzan Nouri Alturki, Soonham S. Yaghmoor & Said S. Moselhy·Journal of Pharmaceutical Research International·2019
It has been well-established that obesity is the major contributing factor forthe development of metabolic syndrome (MetS), diabetes, cardiovascular disease and certain types of cancer. According to WHO, 44% increase of diabetes, 23% increase of ischaemic heart disease, and betwe...
Open access
Research Article10.9734/jpri/2019/v27i230167
Abudukadeer Kuerban, Said S. Moselhy, Hanaa Ghashlan, Taha A. Kumosani, Othman A. S. Baothman, Mustafa Zeyadi, Nawal Helmi, Tahani M. Alghamdi, Mazin A. Zamzami, Muqtadir Baig Mirza, Fareeduddin Quadri Syed, Furkhan Ahmed Mohammed, Abdulrahman L. AL-Malki & Khalid O. Abulnaja·Journal of Pharmaceutical Research International·2017
Aims: Bioactive peptides are acknowledged for their vital contributions to health promotion. This study aims to evaluate antiglycation, antioxidant and antiproliferative ability of peptides derived from tryptic hydrolysis of Soya bean. Place and Duration of Study: Department of B...
Open access
Research Article10.9734/JPRI/2017/37636
Morog R. Maddah, Etimad A. Huwait, Abeer Ali Al-Balawi, Said S. Moselhy, Maryam A. ALghamdi, Mustafa A. Zeyadi, Abdulrahman L. AL-Malki & Taha A. Kumosani·Journal of Pharmaceutical Research International·2019
Background: Oxidative stress is defined as imbalance between oxidant and antioxidant ratio, that lead to oxidative damage of biologically active molecules, finally lead to different disease and initiate carcinogenesis. The drug discovery using natural products as medicinal plants...
Open access
Research Article10.9734/jpri/2019/v26i130124
Abdulrahman L. AL-Malki, Elie K. Barbour, Khadijah S. Balamash, Fawzia A. Alshubaily, Khalid O. Abualnaja, Wesam H. Abdulaal, Mustafa A. Zeyadi, Maryam H. AL-Zahrani, Taha A. Kumosani & Said S. Moselhy·Journal of Pharmaceutical Research International·2019
Aim: This study evaluated the effect of Phyocyanin extracted from Chlorophyta Ulva lactuca algae loaded on albumin nano-particles (ULANP) on diabetic rats. Materials and Methods: Fifty albino rats were divided into 5 goups. GPI: control and GPII: rats were injected with alloxan...
Open access
Research Article10.9734/jpri/2019/v26i430144
Abeer Ali Al-Balawi, Yousri Mohamed Ahmed, Ashwag Albukhari, Shareefa A. ALGhamdi, Mustafa A. Zeyadi, Morog R. Maddah, Etimad H. Huwait, Soad Ali, Taha A. Kumosani & Said S. Moselhy·Journal of Pharmaceutical Research International·2019
Backgound: The generation of oxidative stress can be referred to Aluminium toxic effect in animals and humans. This study aimed to evaluate the role of broccoli (Br) and beetroot (Be) extarcts as antioxidant that prevents oxidative stress that associated with aluminum toxicity. M...
Open access
Research Article10.9734/jpri/2018/v25i330100
Khadijah S. Balamash, Said S. Moselhy, Jehan A. Khan, Etimad H. Huwait, Nawal Helmi, Khalid O. Abulnaja, Widad M. Al-Bishri, Abdulrahman L. AL-Malki, Taha A. Kumosani & Soonham S. Yaghmoor·Journal of Pharmaceutical Research International·2018
Background: Nowadays, alternative medicinal therapy is recommended for protection and management liver diseases. Cinnamon is popular flavoring ingredient, widely used in as additive worldwide. Objective: The mechanism of hepato-protective activity of water (WE) or ethanolic extra...
Open access
Research Article10.9734/JPRI/2018/40272
Abudukadeer Kuerban, Soonham Sami Yaghmoor, Yaaser Q. Almulaiky, Youssri Ahmed Mohamed, Syed Shoeb Iqbal Razvi, Mohammed Nihal Hasan, Said Salama Moselhy, Ayat B. Al-Ghafari, Hadeel M. Alsufiani, Taha A. Kumosani & Abdulrahman L-AL-Malki·Journal of Pharmaceutical Research International·2017
Cruciferous vegetables are rich in glucosinolates, carotenoids, chlorophylls and ascorbic acid which play a major role in the modulation of lipid metabolism and are therefore involved in the lowering of total cholesterol levels in the blood. Cruciferous diet has an inverse relati...
Open access
Research Article10.9734/JPRI/2017/37617