Durational Effect of Cement Dust Exposure on Haematological Profile of Albino Rat

Abstract

Background: This research work studied the durational effects of cement dust inhalation on the haematological parameters of exposed Albino rats. In this study, a glass house animal exposure chamber was fabricated using a plexi-glass and two blowing fans of adjustable revolution. Methodology: Twenty five Albino rats were divided into five groups. Group A served as the control, while group B, C, D and E served as the test, and were exposed for 15, 30, 45 and 60 days interval respectively, for one hour daily to cement dust (200g), at a revolution of 3000rpm of the fans. At the end of the exposure, the animals were sacrificed, blood collected in EDTA bottle and was analysed for some haematological variables. Results: The result showed that there were significant durational increase (p < 0.05) in the levels of Packed Cell Volume (PCV), Haemoglobin (Hb), Red Blood Cell (RBC), Lymphocyte, Monocytes and Eosinophils of the test group compared to control group but there was no significant difference in the Wbc, Basophils, Platelets and Neutrophils levels among the groups (p >0.05). Conclusion: There is a durational exposure haematotoxic effect of cement dust inhalation on rat exposed to cement dust.