Phytochemical and Antioxidant Effect of Spathodea campanulata leaf Extracts
Akharaiyi Fred Coolborn, Boboye Bolatito, Akpambang Victoria Omolara, F. C. Adetuyi
International Journal of Biochemistry Research & Review · pp. 148–159 · Published 4 May 2015
10.9734/IJBCRR/2015/16371Abstract
Phytochemical and Antioxidant Effect of Spathodea campanulata leaf Extracts Aim: Spathodea campanulata is a medicinal plant useful in traditional medicine for the treatment and prevention of some diseases of bacterial and non microbial origins. As a result of this, it becomes very important to investigate the phytochemical and antioxidant (in vitro and in vivo) activities of the plant leaf extracts by chemical methods to ascertain its potential role in folklore medicine. Study Design: In vitro and in vivo by chemical methods. Methodology: 1.5 kg each of S. campanulata air dried leaves ground to powder was extracted separately with ethanol, methanol and petroleum ether at room temperature (25±2°C). Results: The leaf extracts showed qualitatively the presence of saponin, steroid, flavonoids, glycoside, alkaloids, phenol, tannin, terpenoids, phlobatanin and antraquinone. Amount of quantitative phytochemicals screened from the extracts was more in ethanol followed by aqueous, methanol and was least in petroleum ether. Valuable in vitro antioxidant activities were exhibited by the aqueous, ethanol, methanol and petroleum ether extracts in free radical (DPPH), hydroxyl scavenging activities and ferric reducing antioxidant properties. Decrease in values was observed in the in vivo antioxidant assay of glutathione and catalase levels in group of mice infected with Salmonella typhi for three days while there was increase in lipid peroxidation on comparison with negative control value. However improvement in enzymatic antioxidant levels of mice was observed when treated with the plant ethanol leaf extract. The recorded data in the study proposed the use of leaf extract of S. campanulata in traditional medicine hence its inhibition potentials and barrier to generation of free radicals.
Cited by 15
Raveesha Peeriga, Krishnaveni Manubolu · Discover Pharmaceutical Sciences · 2025
E. Rahayuningsih, A. Permana · Research Journal of Textile and Apparel · 2025
Payal Ambhore, Shital Kalekar, Tirthesh Paratwar · Research Journal of Pharmacognosy and Phytochemistry · 2025
Mubasshera Sabir Khan, Syed Ayaz Ali, Awais Badruddoja · International Journal of Innovative Science and Research Technology · 2024
Nurliana Abd Mutalib, N. Yusuf, A. Asari · Malaysian applied biology · 2020
Bayaga Hervé Narcisse, G. Marie, T. Yves · 2020
V. Malarvizhi, K. Sivagamasundari · 2020
V. H. Santos, I. Minatel, G. Lima · Biocatalysis and Agricultural Biotechnology · 2020
B. B. Taika, M. Bouckandou, A. Souza · Journal of Ethnopharmacology · 2018
S. S. Atsafack, N. Kodjio, G. Njateng · 2016
Related research
- In vitro Antioxidant and Anticancer Activity of Cyanobacteria — shares topic coverage
- Review: Parkia speciosa as Valuable, Miracle of Nature — shares topic coverage
- A Selective Review of Lipid Autoxidation and Rancidity, Antioxidants, and Dithiooxamide — shares topic coverage
- Antioxidant and Haemato-Biochemical Enhancing Properties of Daucus carota in Male Wistar Rats Toxicated with Lead Chloride — shares topic coverage
- Radical Scavenging Capacity and Efficacy of Myristica fragrans (Nutmeg) Metabolites on Cladosporum herbarum of Food Origin — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
15
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.