Therapeutic Applications and Multifaceted Benefits of Peppermint Oil in Medicine: A Mini-Review

Abstract

Peppermint oil, a natural product derived from the Mentha × piperita plant, has gained significant attention for its therapeutic versatility across various medical fields. This review examines clinical trials published on PubMed from 2016 to 2024, focusing on its efficacy and safety. Using a systematic approach, studies were selected based on their relevance to human clinical applications. The results highlight peppermint oil's effectiveness in managing gastrointestinal conditions such as irritable bowel syndrome (IBS), reducing chemotherapy-induced nausea, alleviating postoperative pain and anxiety, and enhancing cognitive function and mood. Additionally, its role in improving colonoscopy procedures, preventing pressure injuries, and supporting mental clarity showcases its broad potential. While the evidence supports its application in many areas, the review also identifies limitations, particularly in respiratory health and physical performance enhancements. Overall, peppermint oil emerges as a safe, cost-effective, and accessible complementary therapy with potential for broader use in patient care decrease medical as well as financial burden, hence improving the management of cirrhotic patients. These predictors, however, need further work to validate reliability.