The Genetics of Primary Open Angle Glaucoma Interventions: Therapeutic Directions and Future Predictions

References (49)

1. 1 Genetic Dissection of Complex Traits [DOI]
2. 2 Apoptosis in the nervous system [DOI]
3. 3 Gene therapy restores vision in a canine model of childhood blindness [DOI]
4. 4 Prevalence of Open-Angle Glaucoma Among Adults in the United States [DOI]
5. 5 Adult-Onset Primary Open-Angle Glaucoma Caused by Mutations in Optineurin [DOI]
6. 6 State-of-the-art gene-based therapies: the road ahead [DOI]
7. 7 Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease [DOI]
8. 8 Genes, Genetics, and Epigenetics: A Correspondence [DOI]
9. 9 Analysis of Myocilin Mutations in 1703 Glaucoma Patients From Five Different Populations [DOI]
10. 10 Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1 [DOI]
11. 11 Prolonged delivery of brain-derived neurotrophic factor by adenovirus-infected Müller cells temporarily rescues injured retinal ganglion cells [DOI]
12. 12 Mechanisms of acute axonal degeneration in the optic nerve in vivo [DOI]
13. 13 Viral vectors: a look back and ahead on gene transfer technology.
14. 14 Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma [DOI]
15. 15 Risk reduction and survival benefit of prophylactic surgery in BRCA mutation carriers, a systematic review [DOI]
16. 16 Primary open-angle glaucoma genes [DOI]
17. 17 Dexamethasone alters F‐actin architecture and promotes cross‐linked actin network formation in human trabecular meshwork tissue [DOI]
18. 18 Epigenetics in liver disease: from biology to therapeutics [DOI]
19. 19 Overexpression of optineurin E50K disrupts Rab8 interaction and leads to a progressive retinal degeneration in mice [DOI]
20. 20 Major review: Molecular genetics of primary open-angle glaucoma [DOI]
21. 21 Current concepts on primary open-angle glaucoma genetics: a contribution to disease pathophysiology and future treatment [DOI]
22. 22 Epigenetics and Signaling Pathways in Glaucoma [DOI]
23. 23 State-of-the-art human gene therapy: part I. Gene delivery technologies.
24. 24 Genetic Etiologies of Glaucoma [DOI]
25. 25 Calcineurin cleavage is triggered by elevated intraocular pressure, and calcineurin inhibition blocks retinal ganglion cell death in experimental glaucoma [DOI]
26. 26 Genetic Contributions to Glaucoma: Heritability of Intraocular Pressure, Retinal Nerve Fiber Layer Thickness, and Optic Disc Morphology [DOI]
27. 27 Nanotechnology in ophthalmology [DOI]
28. 28 Mendelian genes in primary open angle glaucoma [DOI]
29. 29 The case for autoimmunity in glaucoma [DOI]
30. 30 Admixture Mapping and the Role of Population Structure for Localizing Disease Genes [DOI]
31. 31 Glaucoma: Present Challenges and Future Trends [DOI]
32. 32 Genes, pathways, and animal models in primary open-angle glaucoma [DOI]
33. 33 Are we ready for genetic testing for primary open-angle glaucoma? [DOI]
34. 34 Regenerative Responses and Axon Pathfinding of Retinal Ganglion Cells in Chronically Injured Mice [DOI]
35. 35 Differential Effects of Myocilin and Optineurin, Two Glaucoma Genes, on Neurite Outgrowth [DOI]
36. 36 Perspectives, Issues and Solutions in RNAi Therapy: the Expected and the Less Expected [DOI]
37. 37 Pharmacology of novel intraocular pressure-lowering targets that enhance conventional outflow facility: Pitfalls, promises and what lies ahead? [DOI]
38. 38 Neuroprotective therapies in glaucoma: II. Genetic nanotechnology tools [DOI]
39. 39 Adenoviral reporter gene transfer to the human trabecular meshwork does not alter aqueous humor outflow. Relevance for potential gene therapy of glaucoma [DOI]
40. 40 Gene therapy for glaucoma: treating a multifaceted, chronic disease.
41. 41 CLINICAL FEATURES ASSOCIATED WITH MUTATIONS IN THE CHROMOSOME 1 OPEN-ANGLE GLAUCOMA GENE ( GLC1A )
42. 42 Primary Open Angle Glaucoma: The Pathophysiolgy, Mechanisms, Future Diagnostic and Therapeutic Directions [DOI]
43. 43 Comprehensive sequencing of the myocilin gene in a selected cohort of severe primary open-angle glaucoma patients [DOI]
44. 44 RNA interference as a gene silencing therapy for mutant MYOC protein in primary open angle glaucoma [DOI]
45. 45 Design considerations in a sib-pair study of linkage for susceptibility loci in cancer [DOI]
46. 46 Gene therapy in glaucoma-3: Therapeutic approaches [DOI]
47. 47 The genetic aspects of adult-onset glaucoma: a perspective from the Greater Toronto area [DOI]
48. 48 Prospects for Genetic Intervention in Primary Open-Angle Glaucoma [DOI]
49. 49 Glaucoma [DOI]

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