Bright Ajoku

Genetic Insights and Epidemiological Models in Understanding Primary Open Angle Glaucoma

Benedict C. Umezurike, Moses O. Akhimien, Chidinma Chukwuka, Thaddaeus C. Ejike, Louis Ugwulor, Bright Ajoku & Solomon N. Ijioma · Ophthalmology Research: An International Journal · 2024

Primary open-angle glaucoma (POAG) is a multifactorial chronic optic neuropathy with significant genetic heterogeneity. The pathogenesis of POAG involves an imbalance between the production and drainage of aqueous humor (AH). Genetic theories suggest that transgenic mice demonstr...

Open access Research Article 10.9734/or/2024/v19i6440

The Genetics of Primary Open Angle Glaucoma Interventions: Therapeutic Directions and Future Predictions

Benedict C. Umezurike, Moses O. Akhimien, Chidinma Chukwuka, Thaedus Ejike, Louis Ugwulor, Bright Ajoku & Solomon N. Ijioma · Ophthalmology Research: An International Journal · 2024

The “multifactorial chronic optic neuropathy” known as primary open angle glaucoma (POAG) is typified by a “progressive loss of retinal ganglion cells (RGC), structural damage to the retinal nerve fiber layer (RNFL) and optic nerve head (ONH), as well as abnormalities in the visu...

Open access Research Article 10.9734/or/2024/v19i5435