The Functional Nutrients of Flaxseed and Their Effect on Human Health: A Review
European Journal of Nutrition & Food Safety · pp. 83–92 · Published 28 Apr 2016
10.9734/EJNFS/2016/16318Abstract
Introduction: Humans have consumed flaxseed (Linum usitatissimum) since the earliest times. It has been used as ready-to-eat breakfast cereals, breakfast drinks, salad dressings, porridge, and as beverages. To date, flaxseed is recognized as a functional food in the world’s food market because of its health benefits besides the basic nutrition. Objectives: To review the functional nutrients of flaxseed with their respective health benefits. Methods: Electronic search of Pub Med, Health Inter Network Access to Research Initiative (HINARI), and Google Scholar databases was conducted. Outcomes of interest were the functional nutrients of flaxseed and potential health benefits mainly; antioxidant, free radical scavenging, anti-carcinogenic, and anti-hypercolesterolemic. Findings: Majority of the articles reviewed showed that flaxseed contains essential nutrients and non-nutrients such as alpha linolenic acid (ALA), lignans known as secoisolariciresinol diglucoside (SDG), and crude fiber that have important health benefits to humans. Conclusions: Eating flaxseed meal in different forms may have beneficial effect in preventing or reducing various forms of cancer, cardiovascular disease, hypertension, diabetes, constipation, diverticular disease and others. Further studies about the Recommended Daily Intake (RDI) and more in vivo studies to ascertain the health benefits of flaxseed nutrients are recommended.
References (32)
- 1 Omega-3 Fatty Acids EPA and DHA: Health Benefits Throughout Life [DOI]
- 2 Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study [DOI]
- 3 Nutrition and cancer: A review of the evidence for an anti-cancer diet [DOI]
- 4 Water-soluble dietary fibers and cardiovascular disease [DOI]
- 5 THE CONTENT AND ANTIOXIDANT ACTIVITY OF PHENOLIC COMPOUNDS IN COLD‐PRESSED PLANT OILS [DOI]
- 6 Flaxseed Lignans: Source, Biosynthesis, Metabolism, Antioxidant Activity, Bio‐Active Components, and Health Benefits [DOI]
- 7 Diversity in lignan biosynthesis [DOI]
- 8 Health effects of omega-3,6,9 fatty acids: Perilla frutescens is a good example of plant oils [DOI]
- 9 Plant and mammalian lignans: A review of source, intake, metabolism, intestinal bacteria and health [DOI]
- 10 Flaxseed gum from flaxseed hulls: Extraction, fractionation, and characterization [DOI]
- 11 Potent Antihypertensive Action of Dietary Flaxseed in Hypertensive Patients [DOI]
- 12 Dietary Flaxseed Inhibits Human Breast Cancer Growth and Metastasis and Downregulates Expression of Insulin-Like Growth Factor and Epidermal Growth Factor Receptor [DOI]
- 13 FLAXSEED AS A SOURCE OF FUNCTIONAL INGREDIENTS [DOI]
- 14 Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type [DOI]
- 15 Flaxseed lignan lowers blood cholesterol and decreases liver disease risk factors in moderately hypercholesterolemic men [DOI]
- 16 Biosynthetic Pathway to the Cancer Chemopreventive Secoisolariciresinol Diglucoside−Hydroxymethyl Glutaryl Ester-Linked Lignan Oligomers in Flax (Linum usitatissimum) Seed [DOI]
- 17 Functional properties and chemical composition of fractionated brown and yellow linseed meal (Linum usitatissimum L.) [DOI]
- 18 Effects of dietary flaxseed on vascular contractile function and atherosclerosis during prolonged hypercholesterolemia in rabbits [DOI]
- 19 Flaxseed as a functional food
- 20 FLAXSEED AND FLAXSEED CAKE AS A SOURCE OF COMPOUNDS FOR FOOD INDUSTRY [DOI]
- 21 Development of Chinese steamed bread enriched in bioactive compounds from barley hull and flaxseed hull extracts [DOI]
- 22 n−3 LC-PUFA-enriched dairy products are able to reduce cardiovascular risk factors: A double-blind, cross-over study [DOI]
- 23 Characteristics of flaxseed hull oil☆ [DOI]
- 24 Flaxseed for Hypertension: Implications for Blood Pressure Regulation [DOI]
- 25 Human Intestinal Bacterium, Strain END-2 Is Responsible for Demethylation as Well as Lactonization during Plant Lignan Metabolism [DOI]
- 26 Enrichment of wheat chips with omega-3 fatty acid by flaxseed addition: Textural and some physicochemical properties [DOI]
- 27 Characterisation of the glycerophospholipid fraction in flaxseed oil using liquid chromatography–mass spectrometry [DOI]
- 28 Determination of phenolic and other polar compounds in flaxseed oil using liquid chromatography coupled with time-of-flight mass spectrometry [DOI]
- 29 Dietary sources of lignans and isoflavones modulate responses to estradiol in estrogen reporter mice [DOI]
- 30 Dietary flaxseed supplementation improves endothelial function in the mesenteric arterial bed [DOI]
- 31 A well balanced omega-6/omega-3 ratio in developing flax bolls after heating and its implications for use as a fresh vegetable by humans [DOI]
- 32 Modeling the recovery patterns from solid phase extraction purification of secoisolariciresinol diglucoside, p-coumaric acid glucoside, and ferulic acid glucoside from microwave-assisted flaxseed extracts [DOI]
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