Successful Treatment of Canine Transmissible Venereal Tumor Using Vincristine Sulfate
Advances in Research · pp. 1–5 · Published 31 Aug 2015
10.9734/AIR/2015/20017Abstract
Transmissible venereal tumor (TVT) is a contagious neoplasm which is common among sexually active dogs, where sexual behaviour is not under control. There are several options for treatment of the tumor and the chemotherapy is the most commonly used. In our study, we investigated the effect of weekly vincristine sulfate administration with a dose of 0,025 mg/kg body weight for 4 weeks in 2 bitches with naturally occurring TVT. Tumors totally regressed in both of the cases and no recurrence was observed. Side effects as depression and decrease in appetite were observed in one of the dogs and leucopenia was observed in both of the bitches for three weeks after the first treatment. In conclusion, although the small numbers of the patients, results of our investigation confirm that vincristine sulfate is an effective chemotherapeutic agent for treatment of TVT in dogs.
References (6)
- 1 Clinical Biochemistry of Domestic Animals [DOI]
- 2 Clonal Origin and Evolution of a Transmissible Cancer [DOI]
- 3 The changing global distribution and prevalence of canine transmissible venereal tumour [DOI]
- 4 Disseminated Transmissible Venereal Tumor in a Dog [DOI]
- 5 Clinico-pathological findings in a case of canine cutaneous metastatic transmissible venereal tumor.
- 6 Comparison of Different Therapeutic Protocols in the Management of Canine Transmissible Venereal Tumour: Review of 30 Cases
Cited by 12
Kevin Alejandro Andrade–Zambrano, Miguel Ángel Chica–Velásquez, Fernando Rincón–Acosta · Revista Científica de la Facultad de Ciencias Veterinarias · 2025
Ronald Elián Zambrano-Moreira, Nadia Cristina Ganchozo-Villegas, María Karolina López-Rauschemberg · Revista de Ciencias Agropecuarias ALLPA · 2025
Moisés Armides Franco-Molina, Yareellys Ramos-Zayas, Erika Evangelina Coronado-Cerda · Immunopharmacology and Immunotoxicology · 2018
Yareellys Ramos Zayas, Moisés Armides Franco Molina, Reyes Tamez Guerra · Journal of Veterinary Research · 2019
A. S. Lepp, E. N. Barsukova, A. V. Ukhlova · Innovations and Food Safety · 2022
Showing 5 of 12 known citations — external sources report more than can currently be individually listed.
Related research
- Metal Based α-glucosidase Inhibitors: Synthesis, Characterization and α-glucosidase Inhibition Activity of Transition Metal Complexes — shares topic coverage
- Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2): What Can Africa Learn from Ongoing Research in Epidemiology, Clinical Manifestations, Chemotherapy and Prevention? — shares topic coverage
- Mantle Cell Lymphoma of Gastrointestinal Tract as a Lead Point for Intussusception: A Case Report — shares topic coverage
- Antimalarial Drug Resistance: An Existential Burden for the Developing World — shares topic coverage
- Feline Mesenteric form of Multinodal Lymphoma: A Case Report — shares topic coverage
Article metrics
Real usage data collected on this platform.
13
Page views
0
PDF downloads
0
Outbound clicks
12
Citations
Views over time
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
Traffic sources
Referring site, by host.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.